Not all vaping is the same: differential pulmonary effects of vaping cannabidiol versus nicotine 

Thorax

This in vivo inhalation study in mice and in vitro cytotoxicity experiments with human cells assessed the pulmonary damage-inducing effects of cannabidiol (CBD) or nicotine aerosols emitted from vaping devices. Inhalation of CBD aerosol resulted in greater inflammatory changes, more severe lung damage, and higher oxidative stress compared with nicotine. CBD aerosol also showed higher toxicity to human cells compared with nicotine.

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