Addiction Medicine Journal Club

How often are patients in MOUD treatment taking extra buprenorphine or methadone? 

Moon KJ, Genberg BL, Astemborski J, German D, Kirk GD, Mehta SH, Feder KA. Concurrent Use of Extra-Medical Medication for Opioid Use Disorder Among Adults Prescribed Methadone or Buprenorphine: A Cohort Study of Urban Adults Who Have Injected Drugs. Drug Alcohol Rev. 2026 Jul;45(5):e70204. doi: 10.1111/dar.70204. PMID: 42376697; PMCID: PMC13316725. 

We also discuss nicotine as a wellness product, and how the FDA approval process for psychedelic drugs is going. 

The conversation: How the pro‑nicotine ‘wellness’ movement rebranded an addictive drug  

NEJM: FDA’s New Framework for Psychedelic Drugs 

Psychiatric Times: FDA Hearing on Psychedelic Medicine Reveals a Field Divided on the Road to Approval 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/  

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

We discuss an article about the mental health consequences of teen cannabis use. 

Young-Wolff KC, Cortez CA, Alexeeff SE, Silver LD, Pacula RL, Slama NE, Padon AA, Satre DD, Campbell CI, Koshy MT, Does MB, Sterling SA. ⁠Adolescent Cannabis Use and Risk of Psychotic, Bipolar, Depressive, and Anxiety Disorders⁠. JAMA Health Forum. 2026 Feb 6;7(2):e256839. doi: 10.1001/jamahealthforum.2025.6839. PMID: 41719031; PMCID: PMC12924094.  

We also discuss a new SAMHSA guide on treating cannabis use disorder, and the lawsuit against META 

SAMHSA: ⁠ADDRESSING CANNABIS USE DISORDER IN PRIMARY CARE SETTINGS—A LIFESPAN APPROACH⁠ 

LA Times: ⁠Is social media addiction real? Law and science collide in blockbuster federal suit⁠ 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to ⁠this link⁠ to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit ⁠MI CARES⁠. 

CME: ⁠https://micaresed.org/courses/podcast-addiction-medicine-journal-club/⁠  

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

We discuss an article about the benefits of continuing buprenorphine, methadone, and naltrexone long-term. 

Hayes CJ, Raciborski RA, Acharya M, Noor NB, Nunes EV, Winhusen TJ. Evaluating the optimal duration of medication treatment for opioid use disorder. Addiction. 2026 Apr;121(4):922-933. doi: 10.1111/add.70211. Epub 2026 Jan 7. PMID: 41501983; PMCID: PMC12980296.  

We also discuss increasing reimbursement for smoking cessation counselling, and VA trials of GLP-1s for alcohol use disorder. 

StatNews: Quitting smoking is hard. A Medicare change may push doctors to give more help 

Medicare proposed 2027 fee schedule (a little light reading) 

To make public comments on the 2027 fee schedule 

Military Times: VA launches trial to test GLP-1 medication for alcohol use disorder in veterans 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/  

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

71-80 Round-Up

Quick summaries of our last 10 articles, for busy people. 

Full citations, for those who love references:

Tuan WJ, Clebak KT, Jawadi E, Snyder J, Zgierska AE. Risk of Oral Health Problems in Adults With Opioid Use Disorder Treated With

Sloan ME, Ngoy A, Xiao KB, Barker B, Buckley L, Fodor M, Hardy K, Hendershot CS, Kahan M, La Fleur S, Le Foll B, Manicone M, Sanches M, Simpkin E, Quilty LC, Wyman J, Tang VM, Bozinoff N. Symptom-Triggered

Smith AM, Shah A, Martin BC. An updated view

Shiwach R, Le Foll B, Alho H, Dunn KE, Strafford S, Zhao Y, Dobbins RL. Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine: A Randomized Clinical Trial. JAMA Netw Open. 2025 Oct 1;8(10):e2537319. doi: 10.1001/jamanetworkopen.2025.37319. PMID: 41085986; PMCID: PMC12522003.

Coughlin LN, Tomlinson DC, Zhang L, Kim HM, Frost MC, Khazanov G, McKay JR, DePhilippis D, Lin LA. Contingency Management for Stimulant Use Disorder and Association With Mortality: A Cohort Study. Am J Psychiatry. 2025 Nov 1;182(11):1016-1023. doi: 10.1176/appi.ajp.20250053. Epub 2025 Sep 10. PMID: 40926572.

Winhusen TJ, Lofwall MR, Kropp F, Lewis D, Smid MC, Young JL, Hodgkins C, Krans EE, Hansen Z, Wachman EM, Schiff DM, Guille C, Rudolf V, Chowdhury T, Leeman L, Lewis M, Matthews AG, Cochran G, King J, Wilder C, Rosa C. Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum: A Randomized Clinical Trial. JAMA

Hooker SA, Rossom RC, Haapala J, Crain AL, Miley K, Olson AW, Kane S, Christensen K, O'Connor PJ, Bart G, Wright EA. External

Sundaresh R, Singh J, Meza J, Saab S, Shetty A. Medications for Alcohol Use Disorder Among Patients With Severe Alcohol-Related Liver Disease. JAMA Netw Open. 2026 Feb 2;9(2):e2559016. doi: 10.1001/jamanetworkopen.2025.59016. PMID: 41670995; PMCID: PMC12895287.

Rosenwohl-Mack S, Heeney M, Samuel L, Anderson E, Herring AA, Sirey LR, Peterson D, Bazazi AR, Snyder H, Suen LW. Outpatient initiation of direct-to-inject buprenorphine. Drug Alcohol Depend. 2026 Jan 1;278:113011. doi: 10.1016/j.drugalcdep.2025.113011. Epub 2025 Dec 19. PMID: 41442975; PMCID: PMC13271074.

Wolpaw BJ, Oren H, Quinnan-Hostein L, Bradley KA, Johnson NJ, Hallgren KA, Gupta A, Kim HN, Granich MA, Steel TL. Hospital-Wide Implementation, Clinical Outcomes, and Safety of Phenobarbital for Alcohol Withdrawal. JAMA Netw Open. 2025 Aug 1;8(8):e2528694. doi: 10.1001/jamanetworkopen.2025.28694. PMID: 40853658; PMCID: PMC12379078.

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This episode does not offer CME, but others do. You can

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group.

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Email: [email protected]

Facebook: @AddictionMedJC

Facebook Group: Addiction Medicine Journal Club

Instagram: @AddictionMedJC

Threads: @AddictionMedJC

YouTube: addictionmedicinejournalclub

Twitter/X: @AddictionMedJC 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 81 we discuss using mirtazapine to treat methamphetamine

We also discuss behavioral treatments added to buprenorphine,

JAMA Network Open: Adjunctive Psychosocial Interventions and Opioid Abstinence Among Patients Receiving Buprenorphine

NBC News: Some ZYN nicotine pouches can be sold as safer than cigarettes, FDA says

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group.

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 80 we discuss phenobarbital for alcohol withdrawal in the hospital.

Wolpaw BJ, Oren H, Quinnan-Hostein L, Et al. Hospital-Wide

We also discuss DEA scheduling of 7-OH (from kratom) and the Trump administration’s pro-alcohol policies.

The Hill: DEA moves to ban opioid-like kratom compound 7-OH

Stat News: Even with MAHA, Trump administration has gone soft on alcohol

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group.

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 79 we discuss an article about starting long-acting injectable buprenorphine without a sublingual test dose. 

We also discuss keeping up with addiction medicine news from the current administration, and an articlre commendation from one of our listeners. 

KFF: The independent source for health policy research, polling, and news. 

KFF: View the Latest: Substance Use 

KFF: Tracking Key Mental Health and Substance Use Policy Actions Under the Trump Administration 

CBS News: New White House drug abuse strategy floats wastewater testing, AI, more treatment and faith-based options

This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/  

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 78 we discuss treating alcohol use disorder in patients with severe liver disease. 

Sundaresh R, Singh J, Meza J, Saab S, Shetty A. Medications for Alcohol Use Disorder Among Patients With Severe Alcohol-Related Liver Disease. JAMA Netw Open. 2026;9(2):e2559016. doi:10.1001/jamanetworkopen.2025.59016    

We also discuss the final dissolution of Perdue Pharma. 

The Guardian: Purdue Pharma to be dissolved as judge approves criminal sentence in opioid case 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/  

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

We love a good poster session. This episode we are joined by Dr. Anthony Accurso to review some of our favorite posters from the American Society of Addiction Medicine’s 2026 Annual Meeting. 

All the Posters from ASAM 57 

Posters profiled here: 

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

--- 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

Finally, an external validation of Epic’s controversial risk of opioid abuse and overdose model. 

Hooker, S.A., Rossom, R.C., Haapala, J. et al. External Validation of Epic’s Risk of Opioid Abuse and Overdose Model Among Primary Care Patients in Three Health Systems. J GEN INTERN MED (2026).  

We also discuss financial consequences of online sports betting, and Trump’s initiative to encourage psychedelic therapy. 

The Financial Consequences of Legalized Sports Gambling 

BMJ: Online gambling requires greater government regulation 

Reuters: Trump signs order to accelerate access to psychedelic drug treatments 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/  

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

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Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices