In episode 60 we discuss

Ezard N,

We also discuss why some

New York Times:The

Pain Therapeutics:Tianeptine,

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This podcast offers category 1

CME:

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Original theme music:composed

Audio editing: Michael

Executive producer:Dr.

A podcast fromArs

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This is

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In episode 59 we discuss

Suen LW, Chiang AY, Jones BLH, Soran CS, Geier M, Snyder HR, Neuhaus J, Myers JJ, Knight KR, Bazazi AR, Coffin PO. Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl. JAMA Netw Open. 2025 Jan 2;8(1):e2456253.

We also discuss impulse control dysregulation from ropinerole, and the new non-opioid painkiller, suzetrigine.

BBC:Prescription medication made me a gambling addict

Grall-Bronnec M, et al.Dopamine agonists and impulse control disorders: a complex association. DrugSaf. 2018;41(1):19-75.

FDA:FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain

Vertex Pharmaceuticals: Randomized, Placebo-Controlled, Phase 3 Trials of Suzetrigine, a Non-Opioid, Pain Signal Inhibitor for Treatment of Acute Pain After

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CME:https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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In episode 58 we discuss a randomized controlled trial of semaglutide for alcohol use disorder. 

Hendershot CS, Bremmer MP, Paladino MB, Kostantinis G, Gilmore TA, Sullivan NR, Tow AC, Dermody SS, Prince MA, Jordan R, McKee SA, Fletcher PJ, Claus ED, Klein KR. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2025 Feb 12:e244789.  

We also discuss benzodiazepine tapering guidelines and new ways to use Sublocade. 

ASAM Clinical Practice Guideline on Benzodiazepine Tapering 

Sublocade label changes 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ 

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode we discuss 4 more articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now.  

Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial. JAMA. 2024 May 28; 331(20):1722-1731. 

Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use: A Post Hoc Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024 Jun 3;7(6):e2417377. 

Understanding the shared meaning of recovery from substance use disorders: New findings from the What is Recovery? Study. Substance Abuse: Research and Treatment, 17, 1–12.  

Long-term buprenorphine treatment for kratom use disorder: A case series. Substance Abuse, 2022. 43(1), 763–766. 

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ASAM Advocacy Center

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Thank you to the Pennsylvania Society of Addiction Medicine!

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ 

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Original theme music: composed and performed by Benjamin Kennedy 

Audio editing: Michael Bonanno 

Executive producer: Dr. Patrick Beeman 

A podcast from Ars Longa Media 

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode we discuss 4 articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now.

Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures. Journal of Substance Use and Addiction Treatment, Volume 158, 2024. 209252, ISSN 2949-8759.

Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024 Mar 4;7(3):e243387.

Association of Cannabis Use With Cardiovascular Outcomes Among US Adults. J Am Heart Assoc. 2024 Mar 5;13(5):e030178.

Association of random and observed urine drug screening with long-term retention in opioid treatment programs. Drug Alcohol Depend. 2024 Feb 1;255:111067.

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ASAM Advocacy Center

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES.

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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Original theme music: composed and performed by Benjamin Kennedy

Audio editing: Michael Bonanno

Executive producer: Dr. Patrick Beeman

A podcast from Ars Longa Media

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group.

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 57 we discuss a new definition of recovery.

Zemore SE, Ziemer KL, Gilbert PA, Karno MP, Kaskutas LA. Understanding the Shared Meaning of Recovery From Substance Use Disorders: New Findings From the What is Recovery? Study. Subst Abuse. 2023 Sep 15;17:11782218231199372.

We also discuss sports betting and why more people aren’t prescribing buprenorphine.

STAT News: The misguided reason why providers aren’t prescribing more buprenorphine for opioid use disorder

Scientific American: How ‘Dark Patterns’ in Sports Betting Apps Keep Users Gambling

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES.

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group.

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 56 we discuss how many attempts it takes to quit using addictive substances.

Fontes RM, Tegge AN, Freitas-Lemos R, Cabral D, Bickel WK. Beyond the first try: How many quit attempts are necessary to achieve substance use cessation? Drug Alcohol Depend. 2024 Dec 8;267:112525. doi: 10.1016/j.drugalcdep.2024.112525. Epub ahead of print. PMID: 39719807.

We also discuss capping nicotine content in cigarettes and how exercise affects cravings.

Reuters: US regulators propose capping nicotine in cigarettes at non-addictive levels

Addictive Behaviors: Ding F, Jia S, Wang P, Liu C, Li Y. Effect of exercise on cravings levels in individuals with drug dependency: A systematic review. Addict Behav. 2024 Nov;158:108127. doi: 10.1016/j.addbeh.2024.108127. Epub 2024 Aug 6. PMID: 39127026.

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES.

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group.

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 55 we discuss the pharmacokinetics and pharmacodynamics of buprenorphine in pregnancy. 

Caritis, Steve N. MD; Venkataramanan, Raman PhD. A Pharmacologic Evaluation of Buprenorphine in Pregnancy and the Postpartum Period. Journal of Addiction Medicine ():10.1097/ADM.0000000000001380, September 2, 2024. 

We also discuss fraud in Baltimore recovery houses, and the doubling of alcohol-related deaths. 

The New York Times: They Entered Treatment. Drugs, Overdoses and Deaths Followed. 

The New York Times: Alcohol Deaths Have More Than Doubled in Two Decades, Study Finds 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ 

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 54 we discuss an article about 24-mg daily of buprenorphine and behavioral health hospitalizations. 

Axeen S, Pacula RL, Merlin JS, Gordon AJ, Stein BD. Association of Daily Doses of Buprenorphine With Urgent Health Care Utilization. JAMA Netw Open. 2024 Sep 3;7(9):e2435478.  

We also discuss the decline in overdose deaths and RFK’s experience with recovery. 

The White House: Biden-⁠Harris Administration Marks Historic Progress Reducing Overdoses Across the Country  

The New York Times: ROBERT KENNEDY JR. ADMITS HE IS GUILTY IN POSSESSING HEROIN 

Robert F. Kennedy: Recovering America - A Film About Healing Our Addiction Crisis 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ 

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice.  

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices

In episode 53 we discuss an article comparing treatment retention and mortality in patients who are prescribed methadone vs. buprenorphine/naloxone for treatment of opioid use disorder. 

Nosyk B, Et al. Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder. JAMA. 2024 Oct 17. 

We also discuss the Modernizing Opioid Treatment Access Act, engaging non-abstinent patients in treatment, and hostility to medications with the recovery community. 

Modernizing Opioid Treatment Access Act (MOTAA) (H.R.1359 / S. 644) 

ASAM: Engagement and Retention of Nonabstinent Patients in Substance Use Treatment 

STAT News: The recovery community says it offers refuge from opioid addiction. But it’s still hostile to lifesaving addiction medications 

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This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. 

CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ 

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This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. 

The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. 

Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. 

Learn more about your ad choices. Visit megaphone.fm/adchoices