OrthoJOE

OrthoJOE

By Mohit Bhandari and Marc SwiontkowskiScienceHealth & Fitness
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OrthoJOE episodes

  • Hot Topics: (1) The Importance of Blinded Assessment of Outcomes in Clinical trials (2) TXA in Hip Fractures

    In this episode, Marc and Mo discuss 3 recent articles that caught their eye. The first part of the discussion focuses on the importance of blinded assessment of outcomes in clinical trials, and the second part focuses on the use of tranexamic acid in patients with hip fractures.

     

    Links:

    • Metcalfe A, Parsons H, Parsons N, Brown J, Fox J, Gemperlé Mannion E, Haque A, Hutchinson C, Kearney R, Khan I, Lawrence T, Mason J, Stallard N, Underwood M, Drew S; START:REACTS team. Subacromial balloon spacer for irreparable rotator cuff tears of the shoulder (START:REACTS): a group-sequential, double-blind, multicentre randomised controlled trial. Lancet. 2022 May 21;399(10339):1954-1963. doi: 10.1016/S0140-6736(22)00652-3. Epub 2022 Apr 21. PMID: 35461618. https://bit.ly/3P62z0I
    •  

      • Verma N, Srikumaran U, Roden CM, Rogusky EJ, Lapner P, Neill H, Abboud JA; SPACE GROUP. InSpace Implant Compared with Partial Repair for the Treatment of Full-Thickness Massive Rotator Cuff Tears: A Multicenter, Single-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2022 Apr 22. doi: 10.2106/JBJS.21.00667. Epub ahead of print. PMID: 35777921. https://bit.ly/3cBTmz6
      •  

        • Porter SB, Spaulding AC, Duncan CM, Wilke BK, Pagnano MW, Abdel MP. Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Intertrochanteric Fracture. J Bone Joint Surg Am. 2022 Jul 6;104(13):1138-1147. doi: 10.2106/JBJS.21.01389. Epub 2022 Apr 29. PMID: 35775092. https://bit.ly/3AHrhjT
        •  

          • POISE Study Group, Devereaux PJ, Yang H, Yusuf S, Guyatt G, Leslie K, Villar JC, Xavier D, Chrolavicius S, Greenspan L, Pogue J, Pais P, Liu L, Xu S, Málaga G, Avezum A, Chan M, Montori VM, Jacka M, Choi P. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008 May 31;371(9627):1839-47. doi: 10.1016/S0140-6736(08)60601-7. Epub 2008 May 12. PMID: 18479744. https://pubmed.ncbi.nlm.nih.gov/18479744/
          •  

            Subspecialties:

            • Shoulder
            • Trauma
            • Hip
            • Orthopaedic Essentials
            • 22 min
            • Gen Z in Orthopaedics and the Unsolved Fracture

              In this episode, Marc and Mo focus on 2 compelling topics that were covered in recent articles. The first part of the discussion focuses on the emergence of Generation Z in orthopaedics (and how this generation differs from both Millennials and Generation Y), while the second part focuses on the treatment of displaced femoral neck fractures with arthroplasty, with a call for additional work in this area.

               

              Links:

              • Siddiqua A, Bhandari M. The ABCs of Generation Z: What Worked for Millennials Will Not Work for Gen Z. OrthoEvidence, Article 38, March 27, 2021. https://myorthoevidence.com/Insight/Show/63
              •  

                • Farey JE, Cuthbert AR, Adie S, Harris IA. Bipolar Hemiarthroplasty Does Not Result in a Higher Risk of Revision Compared with Total Hip Arthroplasty for Displaced Femoral Neck Fractures: An Instrumental Variable Analysis of 36,118 Procedures from the Australian Orthopaedic Association National Joint Replacement Registry. J Bone Joint Surg Am. 2022 May 18;104(10):919-927. doi: 10.2106/JBJS.21.00972. Epub 2022 Feb 17. PMID: 35175973. https://bit.ly/3LNFTA6
                •  

                  • HEALTH Investigators, Bhandari M, Einhorn TA, Guyatt G, Schemitsch EH, Zura RD, Sprague S, Frihagen F, Guerra-Farfán E, Kleinlugtenbelt YV, Poolman RW, Rangan A, Bzovsky S, Heels-Ansdell D, Thabane L, Walter SD, Devereaux PJ. Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture. N Engl J Med. 2019 Dec 5;381(23):2199-2208. doi: 10.1056/NEJMoa1906190. Epub 2019 Sep 26. PMID: 31557429. https://pubmed.ncbi.nlm.nih.gov/31557429/
                  •   

                    Subspecialties:

                    • Hip
                    • Trauma
                    • Orthopaedic Essentials
                    • Education and Training
                    • 22 min
                    • Open Access, Preprints, and Social Media (with special guest Kent Anderson)

                      In this episode, Marc and Mo are joined by special guest Kent Anderson (former CEO of JBJS, founder of The Geyser and The Scholarly Kitchen) in a timely and wide-ranging discussion designed to enlighten the audience on several topics related to scholarly publication, including open access, preprints, technology, social media, peer review, datasets, AI, the roles of editors and publishers, and the human component in knowledge creation.

                       

                      Links:

                      • The Geyser: https://www.the-geyser.com/
                      • The Scholarly Kitchen: https://scholarlykitchen.sspnet.org/
                      • Leopold SS, Haddad FS, Sandell LJ, Swiontkowski M. Clinical Orthopaedics and Related Research, The Bone & Joint Journal, the Journal of Orthopaedic Research, and The Journal of Bone and Joint Surgery Will Not Accept Clinical Research Manuscripts Previously Posted to Preprint Servers. J Bone Joint Surg Am. 2019 Jan 2;101(1):1-4. doi: 10.2106/JBJS.18.01215. PMID: 30601410; PMCID: PMC6319698. https://bit.ly/3yYKblq
                      •  

                        Subspecialties:

                        • Orthopaedic Essentials
                        • 33 min
                        • Spotlight on (1) Reproducibility in Science and (2) Perioperative Nutrition

                          In this episode, Marc and Mo discuss a couple of recent JBJS and OE articles that caught their eye. The first part of the discussion focuses on a number of provocative questions related to the topic of reproducibility in science, while the second part focuses on a recent RCT on the impact of perioperative nutrition on patient outcomes, with a call for additional research in this area.

                           

                          Links:

                          • Bhandari M, Silburt J. Reproducibility in Science: a Crisis in Confidence? Ortho Evidence. 14 May 2022. Article Number 92. https://bit.ly/3NjjKuA
                          • Ioannidis JP. Why most published research findings are false. PLoS Med. 2005 Aug;2(8):e124. doi: 10.1371/journal.pmed.0020124. Epub 2005 Aug 30. PMID: 16060722; PMCID: PMC1182327. https://bit.ly/3Prta9h
                          • Hendrickson NR, Davison J, Glass NA, Wilson ES, Miller A, Leary S, Lorentzen W, Karam MD, Hogue M, Marsh JL, Willey MC. Conditionally Essential Amino Acid Supplementation Reduces Postoperative Complications and Muscle Wasting After Fracture Fixation: A Randomized Controlled Trial. J Bone Joint Surg Am. 2022 May 4;104(9):759-766. doi: 10.2106/JBJS.21.01014. Epub 2022 Mar 14. PMID: 35286282. https://bit.ly/3wzrpQ5
                          •  

                            Subspecialties:

                            • Basic Science
                            • Trauma
                            • Orthopaedic Essentials
                            • 24 min
                            • International Consensus Meeting on VTE (with special guest Javad Parvizi)

                              In this episode, Marc and Mo are joined once again by special guest Javad Parvizi (James Edwards Professor of Orthopaedic Surgery at the Sidney Kimmel School of Medicine at the Rothman Institute at Thomas Jefferson University in Philadelphia) in a follow-up discussion focusing on international efforts to achieve consensus and standardization in orthopaedic care, with a specific focus on the recently published guidelines related to venous thromboembolism.

                               

                              Links:

                              • ICM-VTE Delegates. Recommendations from the ICM-VTE. J Bone Joint Surg Am. 2022 Mar 16;104(Suppl 1):1-162. doi: 10.2106/JBJS.21.01531. https://www.jbjs.org/collection.php?id=19
                              •  

                                Subspecialties:

                                • Basic Science
                                • Education and Training
                                • Ethics
                                • Foot & Ankle
                                • Hand & Wrist
                                • Hip
                                • Infection
                                • Knee
                                • Oncology
                                • Orthopaedic Essentials
                                • Pain Management
                                • Rehabilitation
                                • Pediatrics
                                • Spine
                                • Shoulder
                                • Elbow
                                • Sports Medicine
                                • Trauma
                                • 24 min
                                • Health Disparities Research in Orthopaedics, with Special Guest Kanu Okike

                                  In this episode, Marc and Mo are joined by Kanu Okike (JBJS Deputy Editor for Health Disparities) in a wide-ranging discussion on the multifaceted issue of health disparities in orthopaedics, with a focus on steering the entire field (including researchers, insurers, health systems, funding bodies, and JBJS itself) toward finding meaningful solutions in this important area.

                                   

                                  OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to [email protected]

                                   

                                  Links:

                                  • Okike K. My Grandmother's Knees: A Call for Research on Strategies to Address Racial and Ethnic Disparities in Orthopaedic Surgery. J Bone Joint Surg Am. 2021 Nov 3;103(21):1961-1962. doi: 10.2106/JBJS.21.01081. https://bit.ly/3JYY58R
                                  •  

                                    Subspecialties:

                                    • Basic Science
                                    • Education and Training
                                    • Ethics
                                    • Foot & Ankle
                                    • Hand & Wrist
                                    • Hip
                                    • Infection
                                    • Knee
                                    • Oncology
                                    • Orthopaedic Essentials
                                    • Pain Management
                                    • Rehabilitation
                                    • Pediatrics
                                    • Spine
                                    • Shoulder
                                    • Elbow
                                    • Sports Medicine
                                    • Trauma
                                    • 24 min
                                    • AAOS Clinical Practice Guidelines on OA of the Knee (3rd Edition)

                                      In this episode, Marc and Mo discuss the third edition of the AAOS Clinical Practice Guidelines on Osteoarthritis of the Knee, with a particular focus on the quality of evidence related to injectable therapies and the concept of “living guidelines.” 

                                       

                                      OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to [email protected] 

                                       

                                      Links: 

                                      • AAOS Clinical Practice Guidelines on Osteoarthritis of the Knee (originally released in 2013, update in Aug. 2021. https://bit.ly/3KZI4Rm 
                                      • Vannabouathong C, Bhandari M, Bedi A, Khanna V, Yung P, Shetty V, Khan M. Nonoperative Treatments for Knee Osteoarthritis: An Evaluation of Treatment Characteristics and the Intra-Articular Placebo Effect: A Systematic Review. JBJS Rev. 2018 Jul;6(7):e5. doi: 10.2106/JBJS.RVW.17.00167. https://bit.ly/3uY2t3z 
                                        • Bauer TW. Stem Cell Therapy for Knee Pain—What Exactly Are We Injecting, and Why? Editorial. J Bone Joint Surg. 2016 Sep; 98(15): 1509. doi: 10.2106/JBJS.16.00872. https://bit.ly/3Olf34V 
                                        •  

                                          Subspecialties: 

                                          • Knee 
                                          • Basic Science 
                                          • Orthopaedic Essentials 
                                          • 17 min
                                          • Two Important Topics of Interest: (1) Intimate Partner Violence and (2) TKR After HTO

                                            In this episode, Marc and Mo discuss recent articles on 2 important topics of interest: (1) intimate partner violence in orthopaedic patients and (2) the outcomes of total knee replacement after high tibial osteotomy. They also touch on the recent JBJS supplement on the International Consensus Meeting on Venous Thromboembolism. 

                                             

                                            OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to [email protected] 

                                             

                                            Links: 

                                            • Madden K, Sprague S, Petrisor B, Schneider PS, Kleinlugtenbelt YV, Hackenberg EAM, Garcia-Sanchez Y, Hall JA, Bzovsky S, Thabane L, Bhandari M; PRAISE-2 Investigators. Intimate Partner Violence During Recovery from an Orthopaedic Injury: An Exploratory, Prospective, Multicenter, Observational Cohort Study. J Bone Joint Surg Am. 2022 Mar 16;104(6):512-522. doi: 10.2106/JBJS.21.00421. PMID: 35041623. https://jbjs.org/reader.php?rsuite_id=3175393&native=1&source=The_Journal_of_Bone_and_Joint_Surgery/104/6/512/fulltext&topics=oe#info
                                            •  

                                              • PRAISE Investigators, Sprague S, Bhandari M, Della Rocca GJ, Goslings JC, Poolman RW, Madden K, Simunovic N, Dosanjh S, Schemitsch EH. Prevalence of abuse and intimate partner violence surgical evaluation (PRAISE) in orthopaedic fracture clinics: a multinational prevalence study. Lancet. 2013 Sep 7;382(9895):866-76. doi: 10.1016/S0140-6736(13)61205-2. Epub 2013 Jun 12. PMID: 23768757. https://pubmed.ncbi.nlm.nih.gov/23768757/ 
                                              •  

                                                • Hevesi M, Wilbur RR, Keyt LK, Abdel MP, Levy BA, Saris DBF, Stuart MJ, Krych AJ. Total Knee Arthroplasty Function at 25 Years Following Proximal Tibial Osteotomy: Paired Outcomes of Bilateral TKAs Following Unilateral Osteotomy. J Bone Joint Surg Am. 2022 Mar 16;104(6):552-558. doi: 10.2106/JBJS.21.00761. PMID: 35293891 https://jbjs.org/reader.php?rsuite_id=3164395&native=1&source=The_Journal_of_Bone_and_Joint_Surgery/104/6/552/fulltext&topics=kn#info 
                                                •  

                                                  • International Consensus Meeting on Venous Thromboembolism: https://jbjs.org/collection.php?id=19 
                                                  •  

                                                    Subspecialties: 

                                                    • Orthopaedic Essentials 
                                                    • Trauma 
                                                    • Knee 
                                                    • 22 min
                                                    • JBJS Reviews, Shaking Pete Townshend’s Hand, and Rediscovering What’s Important (with special guest Tom Einhorn)

                                                      In this episode, Marc and Mo are joined by Tom Einhorn, Editor of JBJS Reviews (and accomplished guitarist and singer) in a captivating discussion about the past, present, and future of JBJS Reviews; the practical application of Team Approach and Critical Analysis articles in optimizing patient care; and the importance of maintaining a healthy work-life balance by pursuing creative interests in the arts. (Spoiler alert: in the late 1960’s, Tom’s bands opened for such renowned artists as The Who, Cream, and The Association.)

                                                       

                                                      OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to [email protected]

                                                        

                                                      Links:

                                                      • Tom Einhorn’s cover version of Land of Hope and Dreams by Bruce Springsteen
                                                      • Einhorn TA, Swiontkowski MF. What Types of Articles Does JBJS Reviews Prefer to Publish? JBJS Rev. 2022 Mar 15;10(3). doi: 10.2106/JBJS.RVW.22.00012. PMID: 35290254. The Journal of Bone and Joint Surgery
                                                      •  

                                                        Subspecialties:

                                                        • Basic Science
                                                        • Education and Training
                                                        • Ethics
                                                        • Foot and Ankle
                                                        • Hand and Wrist
                                                        • Hip
                                                        • Infection
                                                        • Knee
                                                        • Oncology
                                                        • Orthopaedic Essentials
                                                        • Pain Management
                                                        • Rehabilitation
                                                        • Pediatrics
                                                        • Spine
                                                        • Shoulder
                                                        • Elbow
                                                        • Sports Medicine
                                                        • Trauma
                                                        • 27 min
                                                        • Two Recent Eye-Catching Studies: Impending vs. Completed Long-Bone Fractures and Cemented vs. Uncemented Hemiarthroplasty for Intracapsular Hip Fracture

                                                          In this episode, Marc and Mo highlight 2 recent JBJS and OrthoEvidence articles that caught their eye: (1) a propensity-matched study focusing on complete and pending fractures in patients with long-bone metastases and (2) an Advanced Clinical Evidence report focusing on the WHiTE-5 trial comparing cemented vs. uncemented hemiarthroplasty for intracapsular hip fracture.

                                                           

                                                          OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to [email protected]

                                                           

                                                          Links:

                                                          • Groot OQ, Lans A, Twining PK, Bongers MER, Kapoor ND, Verlaan JJ, Newman ET, Raskin KA, Lozano-Calderon SA, Janssen SJ, Schwab JH. Clinical Outcome Differences in the Treatment of Impending Versus Completed Pathological Long-Bone Fractures. J Bone Joint Surg Am. 2022 Feb 16;104(4):307-315. doi: 10.2106/JBJS.21.00711. PMID: 34851323.
                                                          •  

                                                            • The WHiTE 5 Trial: Cemented vs. Uncemented Hemiarthroplasty for Intracapsular Hip Fracture. ACE Report. 2022;191(1):2. Available from: https://myorthoevidence.com/AceReport/Report/14311
                                                            •  

                                                              Subspecialties:

                                                              • Oncology
                                                              • Hip
                                                              • Trauma
                                                              • 19 min

                                                              About OrthoJOE

                                                              From the publisher's feed

                                                              Keeping current with orthopaedic science and research. A podcast from JBJS and OrthoEvidence, featuring Mohit Bhandari, MD and Marc Swiontkowski, MD.

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