Today we’re joined by Jannis Born, Ph.D. student at ETH & IBM Research Zurich, to discuss his “PaccMann^RL” research. Jannis details how his background in computational neuroscience applies to this research, how RL fits into the goal of anticancer drug discovery, the effect DL has had on his research, and of course, a step-by-step walkthrough of how the framework works to predict the sensitivity of cancer drugs on a cell and then discover new anticancer drugs.

PaccMann^RL: Designing Anticancer Drugs with Reinforcement Learning w/ Jannis Born - #341

Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

Technology

Tech News

Podcasting

Gadgets

Software How-To

News

Science

Today we're joined by Kirk Marple, CEO and founder of Graphlit, to explore the emerging paradigm of "GraphRAG," or Graph Retrieval Augmented Generation. In our conversation, Kirk digs into the GraphRAG architecture and how Graphlit uses it to offer a multi-stage workflow for ingesting, processing, retrieving, and generating content using LLMs (like GPT-4) and other Generative AI tech. He shares how the system performs entity extraction to build a knowledge graph and how graph, vector, and object storage are integrated in the system. We dive into how the system uses “prompt compilation” to improve the results it gets from Large Language Models during generation. We conclude by discussing several use cases the approach supports, as well as future agent-based applications it enables.

The complete show notes for this episode can be found at twimlai.com/go/681.

GraphRAG: Knowledge Graphs for AI Applications with Kirk Marple - #681

Today we're joined by Alex Havrilla, a PhD student at Georgia Tech, to discuss "Teaching Large Language Models to Reason with Reinforcement Learning." Alex discusses the role of creativity and exploration in problem solving and explores the opportunities presented by applying reinforcement learning algorithms to the challenge of improving reasoning in large language models. Alex also shares his research on the effect of noise on language model training, highlighting the robustness of LLM architecture. Finally, we delve into the future of RL, and the potential of combining language models with traditional methods to achieve more robust AI reasoning.

The complete show notes for this episode can be found at twimlai.com/go/680.

Teaching Large Language Models to Reason with Reinforcement Learning with Alex Havrilla - #680

Today we're joined by Peter Hase, a fifth-year PhD student at the University of North Carolina NLP lab. We discuss "scalable oversight", and the importance of developing a deeper understanding of how large neural networks make decisions. We learn how matrices are probed by interpretability researchers, and explore the two schools of thought regarding how LLMs store knowledge. Finally, we discuss the importance of deleting sensitive information from model weights, and how "easy-to-hard generalization" could increase the risk of releasing open-source foundation models.

The complete show notes for this episode can be found at twimlai.com/go/679.

Localizing and Editing Knowledge in LLMs with Peter Hase - #679

Today we're joined by Jonas Geiping, a research group leader at the ELLIS Institute, to explore his paper: "Coercing LLMs to Do and Reveal (Almost) Anything". Jonas explains how neural networks can be exploited, highlighting the risk of deploying LLM agents that interact with the real world. We discuss the role of open models in enabling security research, the challenges of optimizing over certain constraints, and the ongoing difficulties in achieving robustness in neural networks. Finally, we delve into the future of AI security, and the need for a better approach to mitigate the risks posed by optimized adversarial attacks.

The complete show notes for this episode can be found at twimlai.com/go/678.

Coercing LLMs to Do and Reveal (Almost) Anything with Jonas Geiping - #678

Today we’re joined by Mido Assran, a research scientist at Meta’s Fundamental AI Research (FAIR). In this conversation, we discuss V-JEPA, a new model being billed as “the next step in Yann LeCun's vision” for true artificial reasoning. V-JEPA, the video version of Meta’s Joint Embedding Predictive Architecture, aims to bridge the gap between human and machine intelligence by training models to learn abstract concepts in a more efficient predictive manner than generative models. V-JEPA uses a novel self-supervised training approach that allows it to learn from unlabeled video data without being distracted by pixel-level detail. Mido walks us through the process of developing the architecture and explains why it has the potential to revolutionize AI.

The complete show notes for this episode can be found at twimlai.com/go/677.

PaccMann^RL: Designing Anticancer Drugs with Reinforcement Learning w/ Jannis Born - #341

Download our free app to listen on your phone