Name/Class: Pepcid) Anti-Ucler Agent / H2-Receptor Antagonist

Description: Famotidine is a histamine-2 blocker. It works by decreasing the amount of acid the stomach produces.

Indications: Upper GI Bleed, Anaphylaxis.

Contraindications: Hypersensitivity, Long QT syndrome.

Precautions: Asthma, COPD.

Dosage/Route: 20mg IV

• Gabapentin 
  • Trade - Neurontin 
  • Use – Epilepsy
•  Furosemide 
  • Trade – Lasix
  • Use – CHF/HTN/Edema
• Sertraline HCL
   
  • Trade – Zoloft 
  • Use - Antidepressant

• Description: Sympathomimetic Agonist is a variation of epinephrine used only for inhalation to induce bronchodilation and to reduce laryngeal edema and mucus secretion.
• Indications: Croup (laryngotracheobronchitis).
• Contraindications: Hypersensitivity, hypertension, or epiglottitis.
• Precautions be monitored. : May result in tachycardia and other dysrhythmias. Patient vital signs and ECG should
• Dosage/Route:  0.25-0.75ml of a 2.25% solution in 2.0ml NS 
• Pedi: same as adult.

Just wanted to give you all a heads up that from this point on, I will be copying and pasting each drug slide into the episode description incase anyone wants to follow along with the reading. I tend to also be a visual learner so I need to read along every once in awhile to really help get these memorized. 

I will do my best to go back and update all the previous episodes over the next week or so to make everything consistent across the board. 

As always, if you have any feedback or recommendations, please do not hesitate to let me know. 

Thank You!

• Trade – Benadryl 
• Class – Antihistamine 
• MOA – Antagonizes h1  histamine receptors 
• Indication – Anaphylactic reaction 
• Contraindication – Acute asthma as Benadryl thickens secretions.
• Side effects – Drowsiness, Dizziness, headache, excitable state, wheezing, thickening bronchial secretions, chest tightness, palpitations, hypotension, blurred vision, dry mouth, N/V, Diarrhea. 
• Dosing 
  • Adult 25-50mg IV/IO/IM
  • Pedi 2-12 years – 1-1.25 mg/kg IV/IO/IM

Trade – Nitroquick 

Class – Antianginal agent 

MOA – Relaxes vascular smooth muscle, thereby dilating peripheral arteries and veins. This causes pooling of venous blood and decreased venous return to the heart, which decreases preload. Nitroglycerin also reduces left ventricular systolic wall tension, which decreases afterload.

Indication – Angina, ongoing ischemic chest discomfort, HTN, Myocardial Ischemia associated with cocaine intoxication. 

Contraindication – Hypotension, severe bradycardia or tachycardia, right sided MI, increased ICP, intracranial bleeding, patients taking any medications for erectile dysfunction, known sensitivity to nitrites.

Side effects – Headache, hypotension, bradycardia, lightheadedness, flushing, cardiovascular collapse, methemoglobinemia

Dosing Adult

Sublingual tablets/translingual spray 0.4mg at 5 min intervals for a max of 3 doses

Ointment 2% topical apply 1-2 inches of paste over the chest wall 

IV infusion 5mcg/min may increase rate by 5-10mcg/min every 5 – 10 mins as needed

Pedi

IV infusion – 0.25-0.5 mcg/kg/min titrate up to max dose of 5 mcg/kg/min