Down Syndrome or Trisomy 21, is one of the most commonly encountered syndromes seen in the primary care office. Guidelines for the care of the patient with Down Syndrome has changed several times in the past couple of decades, and in keeping with this tradition, the AAP came out with yet another set of guidelines in May of 2022. This Clinical Report for the Health Supervision of Patients with Down Syndrome is packed with awesome updates and tips of how to successfully navigate the well child encounter, and is a must read for every primary care provider. Here to help us unpack this great bundle of information is Dr. Eyal Ben-Isaac, general pediatrician from CHLA. Explore Our Podcasts: hippoed.com/podcasts