Mike Florio and Myles Simmons discuss the news that Christian McCaffrey is expected to miss a few weeks after suffering a hamstring injury against the Texans. Friday Five: They answer five questions ahead of Sunday's games, including if we'll see fewer taunting penalties, and the best rivalries in the NFL. Plus, they make their picks for what they can't wait to see in Week 3.

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Mike Florio and Myles Simmons discuss the latest in quarterback news, including the status of Andy Dalton, Tua Tagovailoa, Carson Wentz, and Derek Carr. Plus, Florio sounds off on the taunting rule after John Harbaugh comes out in support of it. And Aaron Rodgers clarifies remarks he made in regards to criticism from the media.

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Mike Florio and Charean Williams discuss Ben Roethlisberger's pec injury and how Steelers will need to adjust if he can't play in Week 3. Plus, did the Packers quiet the haters with their blowout win over the Lions? And Michael David Smith joins the show for Week 2 Awards.

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Florio and Charean Williams discuss the latest injury updates around the league including the biggest news that Carson Wentz sprained both sprained ankles during Sunday's game against the Rams. Plus, are they more Week 1 or Week 2: How should we view teams with opposite outcomes in the first two weeks of the season. And a quick preview of Monday Night Football featuring the 0-1 Packers and 0-1 Lions.

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Florio and Myles Simmons give their predictions on this weekend's slate of games, including whether the Ravens will bounce back from their OT loss and if Jalen Hurts will have another big week. Plus, Buy or Sell: QB Edition. Can Tom Brady really play until he's 50, should Taylor Heinicke start the rest of the season, and more.

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Mike and Chris are ready to bounce back in their picks after an underdog-dominated Week 1.

(1:55) Giants-Washington

(5:40) Saints-Panthers

(9:45) Bengals-Bears

(12:55) Texans-Browns

(15:10) Rams-Colts

(18:20) Broncos-Jaguars

(20:00) Bills-Dolphins

(22:40) Patriots-Jets

(24:30) 49ers-Eagles

(27:30) Raiders-Steelers

(30:15) Vikings-Cardinals

(33:55) Falcons-Buccaneers

(36:00) Cowboys-Chargers

(39:15) Titans-Seahawks

(42:05) Chiefs-Ravens

(45:50) Lions-Packers

(49:50) Best Bets & Folsom Prison Blues pick

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Florio and Myles Simmons react to the news that Odell Beckham Jr. will not play against the Texans. Urban Meyer says there's "no chance" he'll be the head coach at USC. Plus, PFT MVP Watch with Pointsbet begins with Week 2 odds.

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Florio and Charean Williams react to Aaron Rodgers comments about the Packers' blowout loss to the Saints being a "learning lesson." They also discuss how 49ers RB Raheem Mostert season-ending knee surgery will impact San Francisco's offense. Plus, Michael David Smith joins the show to take part in handing out some Week 1 Awards.

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Matt Lafleur says the offseason drama didn't influence the Packers' blowout loss to the Saints. With Ryan Fitzpatrick on IR, Ron Rivera says they don't plan to bring in another QB. Plus, Florio and Charean play a game of "Fill in the Blank" based on Sunday's games.

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Oh baby, football is back, and so is the Florio-Simms joint collaboration! After a wild Kickoff game, Chris does his picks from Raymond James Stadium while blocking out the noise (literally).

(2:40) Eagles at Falcons

(5:00) Steelers at Bills

(7:45) Jets at Panthers

(9:40) Vikings at Bengals

(12:45) 49ers at Lions

(14:50) Jaguars at Texans

(16:25) Seahawks at Colts

(19:00) Cardinals at Titans

(20:30) Chargers at Washington

(22:50) Browns at Chiefs

(25:25) Dolphins at Patriots

(27:45) Packers vs Saints (in Jacksonville)

(30:25) Broncos at Giants

(32:25) SNF: Bears at Rams

(34:10) MNF: Ravens at Raiders

(36:20) Best Bets & Folsom Prison Blues Pick

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