Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Vertex Pharmaceuticals experienced a 13% decrease in its share price following the disappointing results of its non-opioid pain therapy, suzetrigine, in a Phase II trial. Meanwhile, major players like Bayer, Bristol Myers Squibb, and Johnson & Johnson announced significant layoffs, impacting hundreds or even thousands of employees. Roche also faced setbacks as their Parkinson's drug failed to meet expectations in a mid-stage trial. Novartis made the decision to cut jobs in both Boston and Munich, while Mesoblast celebrated FDA approval for a mesenchymal stromal cell therapy for GVHD.On a more positive note, the FDA confirmed that there is no shortage of Lilly's GLP-1s and provided compounding pharmacies with a grace period before implementing new regulations to halt their production. Intelligencia AI's accurate pre-ASH predictions for high-potential biotechs demonstrated the efficacy of its predictive AI methodology. Amidst these challenges and changes, the biopharma industry is navigating evolving market dynamics and making strategic decisions to adapt to the shifting landscape.