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Pharmascope Épisode 61: La goutte royale – partie 2


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On continue notre série goutteuse! Dans ce 61ème épisode du Pharmascope, Nicolas, Sébastien et Isabelle discutent des mesures non pharmacologiques et du traitement prophylactique de la goutte.

Les objectifs pour cet épisode sont les suivants:

  • Expliquer les mesures non pharmacologiques utilisées dans le traitement chronique de la goutte
  • Identifier les indications pour débuter un traitement prophylactique en goutte
  • Expliquer les bénéfices et les risques associés aux traitements prophylactiques en goutte

Ressources pertinentes en lien avec l'épisode

Lignes directrices portant sur la prise en charge de la goutte FitzGerald JD et coll. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020;72:879-95.

Richette P et coll. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis. 2020;79:31-8.

Qaseem A et coll. Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017;166:58-68.

Articles de revue portant sur la prise en charge de la goutte Drug and Therapeutics Bulletin. Latest guidance on the management of gout. BMJ. 2018;362:k2893.

Sidari A, Hill E. Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice. Prim Care. 2018;45:213-36.

Dugré N. L'hyperuricémie et la goutte. Québec Pharmacie. Juin/juillet 2015. 25p.

Études portant sur les traitements chroniques de la goutte Badve SV et coll. Effects of Allopurinol on the Progression of Chronic Kidney Disease. N Engl J Med. 2020;382:2504-13.

Doria A et coll. Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes. N Engl J Med. 2020;382:2493-2503.

Kimura K et coll. Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial. Am J Kidney Dis. 2018;72:798-810.

Schumacher Jr HR et coll. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. Arthritis Rheum. 2008;59:1540-8.

Seth R et coll. Allopurinol for chronic gout. Cochrane Database Syst Rev. 2014;10:CD006077.

Ramasamy SN et coll. Allopurinol Hypersensitivity: A Systematic Review of All Published Cases, 1950–2012. Drug Saf. 2013;36:953-80.

White WB et coll. Cardiovascular safety of febuxostat or allopurinol in patients with gout. N Engl J Med 2018;378:1200-10.

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