In episode 620, Mike K and James bring back Danielle Perry, this time to talk about the evidence around the use of colchicine for secondary cardiovascular prevention. There are some large RCTs so we talk about all the numbers and as always put them into the proper context.

Show Notes

MEME conference May8/9 2026 in Vancouver

In episode 619, Mike K and James chat yet again with Émélie Braschi. The topic this time is the use of point-of-care ultrasound (POCUS) to help diagnose patients coming into emerg with dyspnea. The results certainly suggest this may be a useful tool. Tune in and find out if it is useful enough for you.

Show Notes

MEME conference May8/9 2026 in Vancouver

In episode 618, Mike K and James chat with Émélie Braschi who helps us go over, yet again, the evidence for the use of gabapentinoids. This time it is for the treatment of osteoarthritis. We then put the best available evidence into the context of the other treatments we have for osteoarthritis. Have a listen and find out if and/or where it might fit in.

Show Notes

In episode 617, Tina and James bring in Caitlin Finley to review the latest trial that attempts to answer the question of does treating male sexual partners of females undergoing treatment for bacterial vaginosis infection decrease recurrence? We’ll find out that despite this trial getting lots of press it doesn’t provide definitive evidence about who/how to treat. Have a listen as you need to see what the results really show.

Show Notes

In episode 616, Tina and James discuss the issue around the evidence for using topical anesthetics to reduce the pain associated with IUD insertion. To help with this discussion, we bring in Jessica Kirkwood and Caitlin Finley to provide practical information and insight. The evidence is really interesting and worth knowing. So have a listen – it might change your practice.

Show Notes

In episode 615, Mike and James revisit the evidence around using electronic cigarettes for smoking cessation. We look at smoking cessation rates between the use of e-cigarettes, nicotine-free e-cigarettes, nicotine replacement therapy or varenicline. Tune in to hear about the numbers from the trials – it may inform you as to what you could recommend to smokers in your practice.

Show Notes

In episode 614, Mike and James discuss with Caitlin Finley the evidence around a very common primary care question. Does restricting early use of pacifiers result in higher rates of breastfeeding up to 6 months of age in term infants? We discuss the findings and do our best to put the evidence into context.

Show Notes

In episode 613, Mike and James discuss with Jessica Kirkwood the evidence for post-exposure prophylaxis of sexually transmitted infections. We go over the 4 RCTs that have looked at the value of a single dose of doxycycline. It does reduce the risk for some specific infections – but as always you need to know the numbers. We give you all of them and much, much more.

Show Notes

In episode 612, Tina and James chat with Samantha Moe about the use of a recently approved non-hormonal medication being used for vasomotor symptoms in menopause. We go over the 3 available trials and show you the numbers, talk about the limitations and then put the results into the context of hormone and other non-hormonal treatments.

Show Notes

In episode 611, Tina and James talk with Samantha Moe about the use of betablockers and other medications for essential tremor. There is some evidence – much of it from the 1970s, but also some more recent publications. We do our best to tease out all the numbers you need to help you with your recommendations.

Show Notes

Tools For Practice