Guidelines warn about using NSAIDs after myocardial infarction, and a 10-year look-back study from Denmark shows that the warning should be even louder. Whereas current AHA guidelines advise using NSAIDs after MI for the briefest possible time, the Danish study, published last week in Circulation, finds that the risks for death and reinfarction begin within the first week with some NSAIDs, and continue throughout treatment. Diclofenac is especially risky in this context.

Interview-related links:

Circulation abstract (free)

AHA scientific statement on NSAIDs from 2007 (free)