Podcast #352: TXA for Epistaxis

Author: Chris Holmes, M.D.

Educational Pearls:

• TXA: tranexamic acid; used in control of bleeding in major trauma, postpartum hemorrhage, etc.

• In study of 216 patients with epistaxis, TXA placed on a pledget was compared to anterior cotton nasal packing.

• The TXA group had faster time to bleeding control, quicker time to discharge, better patient satisfaction, and lower rates of re-bleeding.

References:

Zahed R, Moharamzadeh P, Alizadeharasi S, Ghasemi A, Saeedi M. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial. Am J Emerg Med. 2013 Sep;31(9):1389-92. doi: 10.1016/j.ajem.2013.06.043.