Contributor: Peter Bakes , MD

Educational Pearls:

• Pediatric Fever + Rash Differential: scarlet fever, measles, rubella, chicken pox, fifth's disease, HHV-6, adenovirus, anaphylaxis, Kawasaki's disease
• Kawasaki's is diagnosed clinically with prolonged fever (>7 days fever in 5 days of fever >6 months with 4 of the following:
• • Strawberry tongue/fissured lips
  • Bilateral conjunctival injection
  • Cervical lymphadenopathy
  • Hand/foot edema
  • Maculopapular rash
• Can develop life threatening coronary artery aneurysms
• Treated with aspirin/IVIG

References

Modesti AM, Plewa MC. Kawasaki Disease. [Updated 2020 Jul 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537163/?report=classic

Ramphul K, Mejias SG. Kawasaki disease: a comprehensive review. Arch Med Sci Atheroscler Dis. 2018;3:e41-e45. Published 2018 Mar 21. doi:10.5114/amsad.2018.74522

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD