Artificial intelligence and electronic health technologies are changing how physicians conceptualize and treat diseases. Although these futuristic advancements are leading to improvements in quality, safety, and patient outcomes, these technologies also are dramatically changing the cyber threat landscape. Kevin W. Lobdell, MD talks with colleagues in cardiothoracic surgery, cardiology, and anesthesiology about embracing virtual reality, augmented reality, and machine learning, while also finding ways to protect against cyberattacks.