Pri-Med Podcasts

By Pri-MedScience

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Pri-Med Podcasts episodes

September 29, 2025Autism and Acetaminophen—Separating Fact from Misinformation - Frankly Speaking Ep 452
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-452
Overview: The healthcare landscape is evolving rapidly, and clinicians are navigating conflicting guidance on established, evidence-based recommendations. Recent news suggest acetaminophen use during pregnancy causes autism spectrum disorder (ASD), which is not the consensus of medical experts based on available data. When guidance from various sources conflicts with established research, clinicians face challenges in providing evidence-based care. Join us to review the current evidence on acetaminophen and ASD risk.
Episode resource links:
Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172

Damkier, P., Gram, E. B., Ceulemans, M., Panchaud, A., Cleary, B., Chambers, C., Weber-Schoendorfer, C., Kennedy, D., Hodson, K., Grant, K. S., Diav-Citrin, O., Običan, S. G., Shechtman, S., & Alwan, S. (2025). Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstetrics and gynecology, 145(2), 168–176. https://doi.org/10.1097/AOG.0000000000005802

Ji Y, Azuine RE, Zhang Y, et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259

Hirota T, King BH. Autism Spectrum Disorder: A Review. JAMA. 2023;329(2):157–168. doi:10.1001/jama.2022.23661

Liu, X., Zou, M., Sun, C., Wu, L., & Chen, W. X. (2022). Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression. Journal of autism and developmental disorders, 52(2), 522–539. https://doi.org/10.1007/s10803-021-04951-8

DSM-5-TR: Neurocognitive Disorders Supplement; October 2022. https://psychiatryonline.org/pb-assets/dsm/update/DSM-5-TR_Neurocognitive-Disorders-Supplement_2022_APA_Publishing.pdf

https://www.npr.org/sections/shots-health-news/2025/09/06/nx-s1-5532143/hhs-responds-to-report-about-autism-and-acetaminophen
Guest: Susan Feeney, DNP, FNP-BC, NP-C

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
17 min
September 22, 2025A Side-by-Side Look at GLP-1 RAs for Weight Loss - Frankly Speaking Ep 451
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-451
Overview: The obesity epidemic has fueled a demand for weight loss medications. Trials have directly compared medications—specifically glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—with a recent study doing just that. Tune in as we explore the evidence comparing semaglutide and tirzepatide for weight loss outcomes up to 1 year.
Episode resource links:
Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064.
Moiz A, Filion KB, Toutounchi H, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. 2025;178(2):199-217.
Wen J, Syed B, Nadora D, et al. Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies. Endocrinol Diabetes Metab. 2025;8(3):e70045.
Guest: Alan M. Ehrlich, MD, FAAFP

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
13 min
September 15, 2025Trying to Quit—Effective Cessation Strategies for Teens Who Vape - Frankly Speaking Ep 450
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-450
Overview: Use of e-cigarettes has increased significantly over the last several years and their popularity continues to grow, notably among adolescents and young adults. Recent evidence indicates that the majority of teens and young adults who vape consider quitting; however, nicotine addiction has historically been difficult to treat in this population. Join us as we discuss the prevalence of vaping, associated harms, and new evidence on the effectiveness of varenicline on cessation.
Episode resource links:
CDC https://www.cdc.gov/tobacco/e-cigarettes/youth.html
Evins, A. E., Cather, C., Reeder, H. T., Evohr, B., Potter, K., Pachas, G. N., Gray, K. M., Levy, S., Rigotti, N. A., Iroegbulem, V., Dufour, J., Casottana, K., Costello, M. A., Gilman, J. M., & Schuster, R. M. (2025). Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial. JAMA, e253810. Advance online publication. https://doi.org/10.1001/jama.2025.3810
Lindson N, Butler AR, McRobbie H, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. 2024;1(1):CD010216. Published 2024 Jan 8. doi:10.1002/14651858.CD010216.pub8
Park-Lee E, Ren C, Sawdey MD, et al. Notes from the Field: E-Cigarette Use Among Middle and High School Students — National Youth Tobacco Survey, United States, 2021. MMWR Morb Mortal Wkly Rep 2021;70:1387–1389. DOI: http://dx.doi.org/10.15585/mmwr.mm7039a4external icon;
Tuisku A, Rahkola M, Nieminen P, Toljamo T. Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial. JAMA Intern Med. 2024;184(8):915–921. doi:10.1001/jamainternmed.2024.1822
Zhang, L., Gentzke, A., Trivers, K. F., & VanFrank, B. (2022). Tobacco Cessation Behaviors Among U.S. Middle and High School Students, 2020. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 70(1), 147–154. https://doi.org/10.1016/j.jadohealth.2021.07.011
Guest: Susan Feeney, DNP, FNP-BC, NP-C

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
18 min
September 08, 2025DASHing Away Colon Cancer - Frankly Speaking Ep 449
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-449
Overview: In this episode, we discuss new evidence linking high compliance with the Dietary Approaches to Stop Hypertension (DASH) diet to lower risks of colorectal cancer, reinforcing the DASH diet’s well-established role in managing hypertension while also highlighting its potential to reduce cancer risk. Gain practical insights into translating these findings into actionable nutrition guidance to support your patients’ overall health.
Episode resource links:
Explain the risk factors for development of colorectal cancers
Review the Dietary Approaches to Stop Hypertension (DASH) and discuss the proposed mechanisms for colorectal cancer reduction by following this approach
Apply evidence from a meta-analysis to support dietary counseling strategies aimed at cancer prevention in clinical settings
Guest: Jillian Joseph, MPAS, PA-C

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
13 min
September 01, 2025Foods Rich in Flavan-3-Ols Reduce Blood Pressure - Frankly Speaking Ep 448
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-448
Overview: Join us to discover how flavan-3-ols, found in tea, cocoa, and select fruits, can support cardiovascular prevention. Learn how to translate emerging evidence on blood pressure and vascular health into practical dietary guidance that empowers your patients and complements standard hypertension care.
Episode resource links:
European Journal of Preventive Cardiology (2025) 00, 1–13. https://doi.org/10.1093/eurjpc/zwaf173
Guest: Robert A. Baldor MD, FAAFP

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
13 min
August 25, 2025Never Too Late to Quit: Years Gained with Tobacco Cessation at Any Age - Frankly Speaking Ep 447
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-447
Overview: New data show that quitting smoking—even at age 65 or 75—can still add years to life. In this episode, we review the latest evidence on life expectancy gains and equip you with effective, evidence-based tools to support tobacco cessation and motivate patients at any age.
Episode resource links:
Le,Thuy TT., Mendez, D. , & Warner, K. (2024). The Benefits of Quitting Smoking at Different Ages. American Journal of Preventive Medicine, 67 (5), 684-688. https://doi.org/10.1016/j.amepre.2024.06.020.
What are the treatments for tobacco dependence? National Institute on Drug Abuse https://nida.nih.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/what-are-treatments-tobacco-dependence
Smokefree.gov offers Apps, counseling, texting support, tools and tips for your patient to build your quit plan
Selby, P., & Zawertailo, L. (2022). Tobacco Addiction. The New England journal of medicine, 387(4), 345–354. https://doi.org/10.1056/NEJMcp2032393
Guest: Jill M. Terrien PhD, ANP-BC

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
15 min
August 18, 2025Patient Portal SOS! Strategies to Tame the In-Basket - Frankly Speaking Ep 446
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-446
Overview: Overwhelmed by in-basket tasks? Discover a practical scheduling intervention that gives you time during the clinic day to manage portal messages. Learn how “portal practice slots” can reduce burnout, improve workflow, and empower you to advocate for changes that support sustainable, high-quality primary care.
Episode resource links:
J Gen Intern Med. DOI: 10.1007/s11606-025-09582-8
Guest: Robert A. Baldor MD, FAAFP

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
12 min
August 11, 2025Metformin: A Fresh Angle for Treating Knee Osteoarthritis - Frankly Speaking Ep 445
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-445
Overview: Managing knee osteoarthritis (OA) in patients with obesity can be challenging, especially when standard treatments fall short. In this episode, we discuss emerging evidence on the use of metformin to reduce knee pain in patients without diabetes and explore how this option could expand your approach to OA management.
Episode resource links:
Pan F, Wang Y, Lim YZ, et al. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial. JAMA. 2025;333(20):1804-1812.
Guest: Alan M. Ehrlich, MD, FAAFP

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
11 min
August 04, 2025Treating Two: Partnering Up Against Bacterial Vaginosis Recurrence - Frankly Speaking Ep 444
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-444
Overview: An estimated 30% of women worldwide are affected by bacterial vaginosis (BV), and although treatment is typically successful, recurrence rates remain high. Traditional strategies, such as treating male partners, have not significantly reduced recurrence. In this episode, we discuss a recent study that used a new approach to partner treatment and review its potential to reduce BV recurrence.
Episode resource links:
Vodstrcil LA, Plummer EL, Fairley CK, et al. Male-partner treatment to prevent bacterial vaginosis. The New England Journal of Medicine. 2025; 392 (10): 947-957. doi: 10.1056/NEJMoa2405404.
DynaMed: https://www-dynamed-com.umassmed.idm.oclc.org/condition/bacterial-vaginosis-bv#GUID-E1A22CF7-D0AC-4247-B1F8-54D1CD26FC1A
Guest: Susan Feeney, DNP, FNP

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
15 min
July 28, 2025Steps That Count: Reducing Cancer Risk Through Physical Activity - Frankly Speaking Ep 443
Credits: 0.25 AMA PRA Category 1 Credit™

CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-443
Overview: In this episode, we evaluate the correlation between an increase in physical activity and step count and a reduction in cancer risk. We break down new evidence, equipping you with practical guidance for counseling patients on simple, impactful behavior changes to support long-term health.
Episode resource links:
Shreves AH, Small SR, Walmsley R, et al. Amount and intensity of daily total physical activity, step count and risk of incident cancer in the UK Biobank. Br J Sports Med. Published online 2025. doi:10.1136/bjsports-2024-109360
Islami, F., Goding Sauer, A., Miller, K.D., Siegel, R.L., Fedewa, S.A., Jacobs, E.J., McCullough, M.L., Patel, A.V., Ma, J., Soerjomataram, I., Flanders, W.D., Brawley, O.W., Gapstur, S.M. and Jemal, A. (2018), Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA: A Cancer Journal for Clinicians, 68: 31-54. https://doi.org/10.3322/caac.21440
Guest: Jillian Joseph, PA-C

Music Credit: Matthew Bugos
Thoughts? Suggestions? Email us at [email protected]
16 min

About Pri-Med Podcasts

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A primary care podcast featuring expert faculty discussing the most recent developments in the medical field. Podcast formats include, but are not limited to: expert clinical discussions, frequently…