Join Henry, Kate, Mark and Gary as they discuss 4 new POEMs: an RCT of mindfulness for chronic pain, use of methotrexate (huh?) for pain relief in adults with knee DJD, a new way to eradicate H., and oral resveratrol for adults with painful DJD of the knee  (you know, the stuff from red wine). And a quiz: what actually are the benefits of lower BP targets?

Links

Mindfulness for chronic pain:  https://pubmed.ncbi.nlm.nih.gov/39158851/

Methotrexate for OA:  https://pubmed.ncbi.nlm.nih.gov/39074374/

Eradicating H. pylori: https://pubmed.ncbi.nlm.nih.gov/38906695/

Resveratrol for OA: https://www.ncbi.nlm.nih.gov/pubmed/39137167

Cochrane Review: Blood pressure targets in adults with hypertension.

This week join our intrepid team of skeptical primary care doctors as Kate, Mark, Henry and Gary discuss a web- and text-based intervention to prevent obesity in babies, the best timing of DOAC initiation after ischemic stroke in adults with atrial fibrillation, using semaglutide for knee osteoarthritis, and the differential diagnosis of thunderclap headaches. Plus the BEST quiz ever.

Links:

Preventing obesity in babies: https://pubmed.ncbi.nlm.nih.gov/39489149/   

https://www.ncbi.nlm.nih.gov/pubmed/39491870

Semaglutide to reduce pain in knee OA: https://pubmed.ncbi.nlm.nih.gov/39476339/

Causes of thunderclap headaches: https://www.ncbi.nlm.nih.gov/pubmed/39303457

This month Kate, Mark, Gary and Henry discuss yoga for treating urinary incontinence in older women, benefits and harms of muscle relaxants for adults with chronic pain, maternal prenatal cannabis use and developmental delays, and bariatric surgery vs. glucagon-like peptide 1 receptor agonists in obese adults with T2DM.

Links:

Yoga for incontinence: https://pubmed.ncbi.nlm.nih.gov/39186785/

Muscle relaxants for painful conditions: https://pubmed.ncbi.nlm.nih.gov/39298168/

Maternal cannabis use and developmental delays: https://pubmed.ncbi.nlm.nih.gov/39422907/

Bariatric surgery vs. GLP-1s: https://www.ncbi.nlm.nih.gov/pubmed/39235379

This week Mark, Kate, Gary and Henry talk about the comparative effectiveness of migraine medications, strategies for adults with plantar fascia pain, whether to continue beta-blocker use after acute MI, and the outcomes of 5-alpha reductase inhibitor use prior to prostate cancer diagnosis.

Links

Migraine: https://www.bmj.com/content/386/bmj-2024-080107

Plantar fasciitis: https://pubmed.ncbi.nlm.nih.gov/38904119/  and https://pubmed.ncbi.nlm.nih.gov/16801514/

Beta-blockers post MI: https://pubmed.ncbi.nlm.nih.gov/39213187/

Prostate cancer: https://pubmed.ncbi.nlm.nih.gov/39190306/

This week listen in as Kate, Mark, Gary and Henry discuss antiviral treatment for infant RSV, colonoscopy competence by specialty, oral minoxidil for hair loss in men, and artificial intelligence performance on interpreting electrocardiograms .

RSV medication:

https://www.nejm.org/doi/full/10.1056/NEJMoa2313551#ap2  and https://pubmed.ncbi.nlm.nih.gov/39321361/ 

Colonoscopy by specialty

https://pubmed.ncbi.nlm.nih.gov/38588561/ 

https://aapce.wildapricot.org/  

Minoxidil:
https://pubmed.ncbi.nlm.nih.gov/38598226/ 

AI for ECGs:
https://www.ncbi.nlm.nih.gov/pubmed/39096711

Join Kate, Gary, Henry and Mark as they discuss a new therapy for dry eye syndrome, antibiotics for suspected UTI in adults with delirium, a new ACG guideline for treating H pylori, and the prevalence of knee pathology in asymptomatic adults. See below for links to the articles and other stuff:

Dry eye treatment

BMJ: https://www.bmj.com/content/386/bmj-2024-080474

Patient instructions: https://www.bmj.com/content/bmj/suppl/2024/09/11/bmj-2024-080474.DC1/liji080474.ww2.pdf

Antibiotics for UTI in delirium: https://pubmed.ncbi.nlm.nih.gov/38895992/

ACG guideline for H. Pylori: https://pubmed.ncbi.nlm.nih.gov/28071659/

Elections and CVD: https://pmc.ncbi.nlm.nih.gov/articles/PMC9021908/

Join Gary, Kate, Mark and Henry as they discuss text messages for adolescent vaping cessation, stopping BP meds in nursing home residents with dementia, the benefits of SGLT-2 inhibitors, and mobile phone app–based artificial intelligence for diagnosing melanoma.

Click here for transcript, notes and links for this episode.

It's biscuit week, oops, I mean flu week here on the Great Primary Care Update. Join our bakers, I mean POETs, as they discuss preventing influenza, treating severe influenza, psychedelics for depression, and GLP-1 agonists to treat sleep apnea of all things.

This week, Gary, Henry, Kate and Mark discuss CV events in children with hypertension, intra-articular steroid injections in adults with hip DJD, the best drug classes for treating adults with T2DM, and AI supported development of practice guideline questions. And a quiz, and two sports stories from Henry!

This week join Kate, Mark, Henry and Gary for a discussion of the cardiovascular benefits of salt substitutes, using virtual reality for cancer-related pain, whether multivitamins reduce mortality, and if and when to recommend vitamin D supplements.