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Editor-in-Chief, Robert Amdur, MD, reviews a paper from the March/April issue of PRO, "Is elective inguinal or external iliac irradiation during neoadjuvant (chemo)radiotherapy necessary for locally advanced lower rectal cancer with anal sphincter invasion?" This paper presents a nomogram to inform the decision about targeting the inguinal and external iliac nodes for elective dose radiotherapy in patients with rectal cancer that involves the anal canal. Other links: Radiation Therapy for Rectal Cancer: Executive Summary of an ASTRO Clinical Practice Guideline