CAR-T immunotherapy- an amazing advance in oncology with high rates of remission, but most patients have complications.  In this podcast we describe the science of CAR-T, physiologic timeline, and imaging features of adverse events which are common.  All radiologists should be aware in order to better help our patients with cancer.  Also, CNS Lupus- increasing in prevalence and still with high mortality.  Learn more about the myriad imaging findings associated with this illness. Imaging Primer on Chimeric Antigen Receptor T-Cell Therapy for Radiologists. de Groot et al.  RadioGraphics 2022; 42:176–194.  Central Nervous System Systemic Lupus Erythematosus: Pathophysiologic, Clinical, and Imaging Features. Ota et al. RadioGraphics 2022; 42:212–232.

In our first podcast of 2022, we learn about a life-threatening entity that is more common that we thought, and important for radiologists in all specialties to recognize:  Spontaneous Coronary Artery Dissection.  Also, pearls and pitfalls for distinguishing malignant, benign, and incidental findings on FDG PET/CT.

Spontaneous Coronary Artery Dissection: An Underdiagnosed Clinical Entity—A Primer for Cardiac Imagers. Aslam et al. RadioGraphics 2021; 41:1897–1915. 

Common Skeletal Neoplasms and Nonneoplastic Lesions at 18F-FDG PET/CT. Cheung et al. RadioGraphics 2022; 42:250–267.

ECMO is an important, last resort to save many of our patients with cardiopulmonary failure and we are seeing it used in our sickest COVID patients.  Do you know how it works?  Imaging plays a vital role in assessing the complications of ECMO, but the hemodynamic alterations and artifacts make CTA tricky.  Dr. Ross Frederick summarizes this new ECMO paper and additional information on how to do it right.

CT Angiography of Venoarterial Extracorporeal Membrane Oxygenation. Shen et al. RadioGraphics 2022; 42. 

This week on the Radiographics podcast, Informatics editors Drs. Juluru and Wang summarize recent papers on Natural language processing and Deep Learning. 

Bag-of-Words Technique in Natural Language Processing: A Primer for Radiologists. Juluru et al. RadioGraphics 2021; 41:1420–1426.

Deep Learning: An Update for Radiologists. Cheng et al. RadioGraphics 2021; 41:1427–1445.

In this podcast, Ross Frederick describes a promising new interventional radiology treatment for an extremely common source of morbidity around the world:  knee osteoarthritis.  And Wende Gibbs summarizes a multisystem paper describing the ever growing number of treatment related complications we might encounter in our cancer patients- we must be familiar with the possibilities to get them the best possible care!

Side Effects of Oncologic Treatment in the Chest: Manifestations at FDG PET/CT. Lang et al. RadioGraphics 2021; 41:2071–2089.

Geniculate Artery Embolization: Role in Knee Hemarthrosis and Osteoarthritis. Heller et al. 

Amyloid—the devious protein that when misfolded can cause serious incurable disease in nearly every body system. Wende Gibbs discusses a new article about amyloidosis, and Ross Frederick summarizes a new Rad-Path article on pituitary gland tumors in this week's RadioGraphics podcast. 

Amyloidosis: Multisystem Spectrum of Disease with Pathologic Correlation. Sugi et al. RadioGraphics 2021; 41:1454–1474

Primary Tumors of the Pituitary Gland: Radiologic-Pathologic Correlation. Shih et al. RadioGraphics 2021; 41:2029–2046

Acute, life-threatening GI bleeding- a frightening thing to find on call!  So many causes- do you know what they all look like?  Ross Frederick summarizes a valuable new atlas from the new Radiographics body imaging monograph. And from the Sept/Oct issue, Wende Gibbs summarizes updates in breast cancer lymph node imaging and intervention.

Gastrointestinal Bleeding at CT Angiography and CT Enterography: Imaging Atlas and Glossary of Terms. Guglielmo et al. RadioGraphics 2021; 41:1632–1656.

Imaging Updates to Breast Cancer Lymph Node Management. Chung et al. RadioGraphics 2021; 41:1283–1299.

The newest podcast highlights our monograph series, this time Emergency Neuroradiology - vital knowledge for all. Ross Frederick and Wende Gibbs discuss neck and skull base emergencies and the etiologies associated with the emergency presentation of headache - common but so important.

Acute Headache in the Emergency Setting. Guryildirim et al.  RadioGraphics 2019; 39:1739–1759. 

Traumatic Neck and Skull Base Injuries. Go et al. RadioGraphics 2019; 39:1796–1807.

This week's podcast features a useful approach to the common and difficult case of the cystic abdominal or pelvic mass, as well as the LI-RADS diagnostic algorithm for hepatocellular carcinoma. (And a brief bonus commentary on radiology reporting!)

How to Use LI-RADS to Report Liver CT and MRI Observations. Cunha et al. RadioGraphics 2021; 41:1352–1367

Approach to Cystic Lesions in the Abdomen and Pelvis, with RadiologicPathologic Correlation. Yacoub et al. RadioGraphics 2021; 41:1368–1386

In this podcast: a life-saving review of soft tissue infections, like the dreaded necrotizing fasciitis, seen by radiologists of all subspecialities. And a discussion of metabolic bone disease, primarily osteoporosis - more common, underdiagnosed, undertreated, and deadly than people think!

Soft-Tissue Infections and Their Imaging Mimics: From Cellulitis to Necrotizing Fasciitis. Hayeri et al. RadioGraphics 2016; 36:1888–1910.

Imaging Findings of Metabolic Bone Disease. Chang et al. RadioGraphics 2016; 36:1871–1887.