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Editor-in-Chief, Robert Amdur, MD, discusses the issues related to using a rectal spacer with prostate radiotherapy that is both radiopaque and viscous. The foundation of the discussion is a paper published in the 2024 January/February issue of PRO: “Application of a Radiopaque Viscous Hydrogel Spacer for Prostate Cancer Radiation Therapy: A Prospective Phase 2 Study” with PMID 37791943. A related paper “Barrigel Spacer Injection Technique” with PMID 37657504 was also published in the issue of PRO.