While stranded waiting for their ship to be released from quarantine, Dr. and Mrs. Macphail must share lodging with the insufferable Davidsons—self-righteous and over-zealous missionaries who also happen to be the only polite company on the god-forsaken island near Pago-Pago.

But, things take a dreadful and unexpected turn when Mr. Davidson takes it upon himself to rescue the soul of their neighbor downstairs from second cabin—the insolent, carousing, and inimitable Miss Sadie Thompson.

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