Sue Yom, Editor-in-Chief, co-hosts with Dr. Michelle Kim, Professor and Co-Chair of the Cancer Center's Neuro-Oncology Clinical Research Team at the University of Michigan, and our journal’s section lead for the CNS section. Our guests are Dr. Joshua Palmer, Associate Professor at Ohio State University and supervising author on the article, Dose/volume tolerance of the brain and predictors of radiation necrosis after three fraction radiosurgery for brain metastases: A large single-institutional analysis, and Dr. Arjun Sahgal, Chair and Professor at the Odette Cancer Centre of the Sunnybrook Health Sciences Centre, and supervising author on the article, Systematic Review Informing The Management of Symptomatic Brain Radiation Necrosis after Stereotactic Radiosurgery and International Stereotactic Radiosurgery Society (ISRS) Recommendations.