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Editor-in-Chief Dr. Sue Yom and Physics Section and Executive Editor Dr. David Carlson, Professor, Vice Chair, and Director of Medical Physics at Yale University, host a discussion of current research frontiers in particle therapy. Our guests (calling in from PTCOG!) are Dr. Tracy Underwood, Senior Physicist at Leo Cancer Care and one of the supervising authors of Proposing a Clinical Model for RBE Based on Proton Track-End Counts, and Dr. Andrea Mairani, Group Leader of Biophysics at Heidelberg Ion Beam Therapy Center and supervising author of Commissioning of Helium Ion Therapy and the First Patient Treatment With Active Beam Delivery.