There are places in your body where bacteria normally reside. But what happens when they move to a different location?

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In a recent study looking at 13 different trials the researach observes to hwat degree PPI medication altered gut bacteria. What they found was concerning.

Oral bacteria normally confined to the mouth moved (translocated) and proliferated further down the GI tract. As an example, Strep, proliferated in just 7 days of using a PPI.

Esophagus bacteria shifted too, causing refllux symptoms even without excess acid.

These shifts explain why PPI meds can increase infections, SIBO, system inflammation and overall dysbiosis. 

One infection, C diff (Clostridium difficile) is one of the best known connections to PPIs - proven to double the risk. It causes colitis with severe diarrhea and can become life threatening. 

Why does this happen? When you take a PPI you raise the pH in your stomach and you lose good bacteria while allowing bad bacteria to multiply. There also an issue with bile not being converted properly which allows this bacteria (and other bad bacteria) to multiply.

SIBO symptoms include gas, bloating, constipation or diarrhea, rosacea, osteoporosis, generalized malabsorption, along with creating a deficiency of fat soluble vitamins - A, D, E, and K.

Causing systemic inflammation factually increases your risk for obesity, a weakened immune system, diabetes, IBS, heart disease, autoimmune diseases, certain cancers, anxiety and cognitive decline. 

To summate, here's what the authors of the study said: PPI use may be one of the strongest factors shaping dysbiosis in populations. 

Finding a clinician to help you get to the root cause of your reflux so that you can wean down or off your PPI could make a big impact on your health.

If you'd like help we're here for you. The best next step is to contact us for a consultation and then we can determine if what we do is a good fit for you. Call 727-335-0400.

Reference
Fossmark & Olaisen (2024) Microorganisms. “Changes in the Gastrointestinal Microbiota Induced by Proton Pump Inhibitors — A Review of Findings from Experimental Trials” 

#guthealth #acidreflux #rootcausemedicine 

Disclaimer: The information provided in this video is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your physician or other qualified health provider with any questions you may have regarding your health, medical condition, or treatment options. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this video.
The views expressed are based on my clinical experience and current scientific understanding as of the date of publication. Individual results may vary.