This article "Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii" is published in Nature Chemical Biology.

Author: Gary Liu

Journal: Nature Chemical Biology

Year: 2023

Podcast type: Short

The authors are:

⦁ Gary Liu

⦁ Denise B. Catacutan

⦁ Khushi Rathod

⦁ Kyle Swanson

⦁ Wengong Jin

⦁ Jody C. Mohammed

⦁ Anush Chiappino-Pepe

⦁ Saad A. Syed

⦁ Kenneth Rachwalski

⦁ Meghan Fragis

⦁ Michael G. Surette

⦁ Brian K. Coombes

⦁ Jakob Magolan

⦁ Tommi Jaakkola

⦁ Regina Barzilay

⦁ James J. Collins

⦁ Jonathan M. Stokes

Affiliations:

Gary Liu, Denise B. Catacutan, Khushi Rathod, Kyle Swanson, Jody C. Mohammed, Kenneth Rachwalski, Meghan Fragis, Brian K. Coombes, Jakob Magolan, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

Michael G. Surette, Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Tommi Jaakkola, Wengong Jin, Regina Barzilay, Computer Science and Artificial Intelligence Laboratory (CSAIL), Massachusetts Institute of Technology, Cambridge, MA, USA

Anush Chiappino-Pepe, James J. Collins, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA

Anush Chiappino-Pepe, Swiss Institute of Bioinformatics, Lausanne, Switzerland

James J. Collins, Broad Institute of MIT and Harvard, Cambridge, MA, USA

James J. Collins, Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA

Jonathan M. Stokes, David Braley Centre for Antibiotic Discovery, McMaster University, Hamilton, Ontario, Canada

This article "AI-driven multi-omics integration for multi-scale predictive modeling of genotype-environment-phenotype relationships" is published in Computational and Structural Biotechnology Journal.

Author: You Wu

Journal: Computational and Structural Biotechnology Journal

Year: 2025

Podcast type: Short

The authors are:

⦁ You Wu

⦁ Lei Xie

Affiliations:

You Wu, Lei Xie, Ph.D. Program in Computer Science, The Graduate Center, The City University of New York, New York, NY, USA

Lei Xie, Ph.D. Program in Biology and Biochemistry, The Graduate Center, The City University of New York, New York, NY, USA

Lei Xie, Department of Computer Science, Hunter College, The City University of New York, New York, NY, USA

Lei Xie, Helen & Robert Appel Alzheimer’s Disease Research Institute, Feil Family Brain & Mind Research Institute, Weill Cornell Medicine, Cornell University, New York, NY, USA

This article "Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling" is published in Nature.

Author:⁠ Elizabeth J. Culp

Journal: Nature

Year: 2020

Podcast type: Short

The authors are:

⦁ Elizabeth J. Culp

⦁ Nicholas Waglechner

⦁ Wenliang Wang

⦁ Aline A. Fiebig-Comyn

⦁ Yen-Pang Hsu

⦁ Kalinka Koteva

⦁ David Sychantha

⦁ Brian K. Coombes

⦁ Michael S. Van Nieuwenhze

⦁ Yves V. Brun

⦁ Gerard D. Wright

Affiliations:

Elizabeth J. Culp, Nicholas Waglechner, Wenliang Wang, Aline A. Fiebig-Comyn, Kalinka Koteva, David Sychantha, Brian K. Coombes, Gerard D. Wright, M. G. DeGroote Institute for Infectious Disease Research, David Braley Centre for Antibiotic Discovery, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

Yen-Pang Hsu, Michael S. Van Nieuwenhze, Department of Chemistry, Indiana University, Bloomington, IN, USA

Yves V. Brun, Department of Biology, Indiana University, Bloomington, IN, USA

Yves V. Brun, Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada

This article "Dual CRISPRi-seq for genome-wide genetic interaction studies identifies key genes involved in the pneumococcal cell cycle" is published in Cell Systems.

Author: Julien Dénéréaz

Journal: Cell Systems

Year: 2025

Podcast type: Expert

The authors are:

• Julien Dénéréaz
• Elise Eray
• Bimal Jana
• Vincent de Bakker
• Horia Todor
• Tim van Opijnen
• Xue Liu
• Jan-Willem Veening

Affiliations:

Julien Dénéréaz, Elise Eray, Vincent de Bakker, Jan-Willem Veening, Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland

Bimal Jana, Tim van Opijnen, Broad Institute of MIT and Harvard, Cambridge, MA, USA

Bimal Jana, Tim van Opijnen, Division of Infectious Diseases, Department of Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

Vincent de Bakker, Department of Microbiology, Harvard Medical School, Boston, MA, USA

Horia Todor, Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA

Xue Liu, Department of Pathogen Biology, International Cancer Center, Shenzhen University Medical School, Shenzhen 518060, China

This article "AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome" is published in Nature Medicine.

Author:⁠⁠ Ruoyun Xiong

Journal: Nature Medicine

Year: 2025

Podcast type: Short

The authors are:

⦁ Ruoyun Xiong

⦁ Elizabeth Aiken

⦁ Ryan Caldwell

⦁ Suzanne D. Vernon

⦁ Lina Kozhaya

⦁ Courtney Gunter

⦁ Lucinda Bateman

⦁ Derya Unutmaz

⦁ Julia Oh

Affiliations:

Ruoyun Xiong, Julia Oh, Duke University, Durham, NC, USA

Courtney Gunter, Ruoyun Xiong, The University of Connecticut Health Center, Farmington, CT, USA

Elizabeth Aiken, Ryan Caldwell, Lina Kozhaya, Derya Unutmaz, Julia Oh, The Jackson Laboratory, Farmington, CT, USA

Suzanne D. Vernon, Lucinda Bateman, Bateman Horne Center, Salt Lake City, UT, USA

This article "Machine learning analysis of RB-TnSeq fitness data predicts functional gene modules in Pseudomonas putida KT2440" is published in mSystems.

Author:⁠⁠ Andrew J. Borchert

Journal: mSystems

Year: 2024

Podcast type: Short

The authors are:

⦁ Andrew J. Borchert

⦁ Alissa C. Bleem

⦁ Hyun Gyu Lim

⦁ Kevin Rychel

⦁ Keven D. Dooley

⦁ Zoe A. Kellermyer

⦁ Tracy L. Hodges

⦁ Bernhard O. Palsson

⦁ Gregg T. Beckham

Affiliations:

Andrew J. Borchert, Alissa C. Bleem, Keven D. Dooley, Zoe A. Kellermyer, Tracy L. Hodges, Gregg T. Beckham, National Renewable Energy Laboratory, Golden, Colorado, USA

Alissa C. Bleem, Keven D. Dooley, Tracy L. Hodges, Gregg T. Beckham, Renewable and Sustainable Energy Institute, University of Colorado Boulder, Boulder, Colorado, USA

Andrew J. Borchert, Alissa C. Bleem, Gregg T. Beckham, Department of Chemistry, Colorado School of Mines, Golden, Colorado, USA

Hyun Gyu Lim, Kevin Rychel, Bernhard O. Palsson, Department of Bioengineering, University of California San Diego, La Jolla, California, USA

Hyun Gyu Lim, Bernhard O. Palsson, Systems Biology Research Group, University of California San Diego, La Jolla, California, USA

Hyun Gyu Lim, Bernhard O. Palsson, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark

Bernhard O. Palsson, Hyun Gyu Lim, Bioinformatics Research Center, University of California San Diego, La Jolla, California, USA

This article "From mental power to muscle power—gaining strength by using the mind" is published in Neuropsychologia.

Author:⁠⁠ Vinoth K. Ranganathan

Journal: Neuropsychologia

Year: 2004

Podcast type: Short

The authors are:

⦁ Vinoth K. Ranganathan

⦁ Vlodek Siemionow

⦁ Jing Z. Liu

⦁ Vinod Sahgal

⦁ Guang H. Yue

Affiliations:

Vinoth K. Ranganathan, Vlodek Siemionow, Jing Z. Liu, Guang H. Yue, Department of Biomedical Engineering/ND20, The Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA

Vlodek Siemionow, Vinod Sahgal, Department of Physical Medicine & Rehabilitation, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA

Guang H. Yue, Orthopedic Research Center, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA

This article "L-theanine suppresses the metastasis of prostate cancer by downregulating MMP9 and Snail" is published in Journal of Nutritional Biochemistry.

Author:⁠⁠ Xirui Fan

Journal: Journal of Nutritional Biochemistry

Year: 2021

Podcast type: Short

The authors are:

⦁ Xirui Fan

⦁ Jinyi Zhou

⦁ Xiaowen Bi

⦁ Juanjuan Liang

⦁ Shuai Lu

⦁ Xintong Yan

⦁ Lan Luo

⦁ Zhimin Yin

Affiliations:

Xirui Fan, Jinyi Zhou, Xiaowen Bi, Juanjuan Liang, Shuai Lu, Xintong Yan, Zhimin Yin, Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China

Lan Luo, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, People’s Republic of China

This article "Bacteria use a decoy defence to fight viruses" is published in Nature.

Author:⁠⁠ Malcolm F. White

Journal: Nature

Year: 2025

Podcast type: Short

The authors are:

⦁ Malcolm F. White

Affiliations:

Malcolm F. White, School of Biology, University of St Andrews, St Andrews KY16 9ST, UK

This article “Artificial intelligence in metabolic research” is published in Nature Metabolism.

Author:Jens Juul Holst

Journal: Nature Metabolism

Year: 2025

Podcast type: Short

The authors are:

• Jens Juul Holst
• Camilla Schéele
• Philipp E. Scherer
• Weiping Jia
• Eran Segal
• Nikolai Slavov
• Ruth J. F. Loos
• Golnaz Vahedi
• Lei Sun
• M. Madan Babu
• Melissa D. McCradden
• Peter G. Jacobs

Affiliations:

Jens Juul Holst, Camilla Schéele— Department of Biomedical Sciences, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Philipp E. Scherer — Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA

Weiping Jia— Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; Institute for Proactive Healthcare, Shanghai Jiao Tong University, Shanghai, China

Eran Segal — Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel; Mohamed bin Zayed University of Artificial Intelligence, Abu Dhabi, United Arab Emirates

Nikolai Slavov — Department of Bioengineering, Northeastern University, Boston, MA, USA; Parallel Squared Technology Institute, Watertown, MA, USA

Ruth J. F. Loos — Charles Bronfman Institute for Personalized Medicine, Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Golnaz Vahedi — Department of Genetics; Institute for Immunology and Immune Health; Epigenetics Institute; Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Lei Sun — TaiKang Center for Life and Medical Sciences, TaiKang Medical School, Wuhan University, Wuhan, China; Cardiovascular & Metabolic Disorders, DUKE-NUS Medical School, Singapore, Singapore; State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan, China

M. Madan Babu — St. Jude Children’s Research Hospital, Memphis, TN, USA

Melissa D. McCradden — Australian Institute for Machine Learning, The University of Adelaide, Adelaide, South Australia, Australia; Women’s and Children’s Health Network, North Adelaide, South Australia, Australia; SickKids Research Institute, Toronto, Ontario, Canada

Peter G. Jacobs — Artificial Intelligence for Medical Systems Lab, Oregon Health & Science University, Portland, OR, USA; School of Chemical, Biological, and Environmental Engineering, College of Engineering, Oregon State University, Corvallis, OR, USA; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA