The U.S. War Department created the first antecedent of the U.S. Air Force, as a part of the U.S. Army, on 1 August 1907, which through a succession of changes of organization, titles, and missions advanced toward eventual independence 40 years later. In World War II, almost 68,000 U.S. airmen died helping to win the war, with only the infantry suffering more casualties. In practice, the U.S. Army Air Forces (USAAF) was virtually independent of the Army during World War II, and in virtually all ways functioned as an independent service branch, but airmen still pressed for formal independence. The National Security Act of 1947 was signed on 26 July 1947 by President Harry S Truman, which established the Department of the Air Force, but it was not until 18 September 1947, when the first secretary of the Air Force, W. Stuart Symington, was sworn into office that the Air Force was officially formed as an independent service branch.

The act created the National Military Establishment (renamed Department of Defense in 1949), which was composed of three subordinate Military Departments, namely the Department of the Army, the Department of the Navy, and the newly created Department of the Air Force. Prior to 1947, the responsibility for military aviation was shared between the Army Air Forces and its predecessor organizations (for land-based operations), the Navy (for sea-based operations from aircraft carriers and amphibious aircraft), and the Marine Corps (for close air support of Marine Corps operations).