Today, we discuss the rise of GLP-1 receptor agonists - what they are, how they work, and how they affect fasting during the perioperative period. 

Resources for today's episode:

StatPearls: Physiology, Gastrointestinal Hormonal Control by Parikh, A. & Thevenin, C.
https://www.ncbi.nlm.nih.gov/books/NBK537284/

StatPearls: Glucagon-like Peptide-1 Receptor Agonists by Collins, L. & Costello, R.
https://www.ncbi.nlm.nih.gov/books/NBK551568/ 

ANZCA PG07(A) Appendix
https://www.anzca.edu.au/getattachment/897f5bf5-b665-4c99-a56f-e72678f19f7e/PG07(A)-Appendix-1-%E2%80%93-Fasting-guideline 

ADS-ANZCA Perioperative and Hyperglycaemia Guidelines (Adults)
https://www.diabetessociety.com.au/wp-content/uploads/2023/03/ADS-ANZCA-Perioperative-Diabetes-and-Hyperglycaemia-Guidelines-Adults-November-2022-v2-Final.pdf 

Up To Date: Glucagon-like peptide 1-based therapies for the treatment of type 2 diabetes mellitus by Dungan, K. & DeSantis, A.
https://www.uptodate.com/contents/glucagon-like-peptide-1-based-therapies-for-the-treatment-of-type-2-diabetes-mellitus#:~:text=Like%20native%20GLP%2D1%2C%20all,%27Glycemic%20efficacy%27%20below.) 

American Society of Anesthesiologists Consensus-Based Guidance on Preoperative Management of Patients (Adults and Children) on Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists by Joshi, G. et al.
https://www.asahq.org/about-asa/newsroom/news-releases/2023/06/american-society-of-anesthesiologists-consensus-based-guidance-on-preoperative

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Feel free to email us at [email protected] if you have any questions, comments or suggestions. We love hearing from you!

And don't forget to claim CPD for listening if you are a consultant or fellow. Log us as a learning session which you can find within the knowledge and skills division, and as evidence upload a screenshot of the podcast episode.

Thanks for listening, and happy studying!