The resignations of senior leaders at the CDC is a calamity. People with decades of expertise in infectious disease are leaving the agency because the new director—who Trump just appointed—refused to get on board with RFK's anti-vax crusade, including limiting access to Covid boosters. And Wednesday's violence in Minneapolis may be a sign that the FBI should be keeping its eye on the threats from domestic terror instead of arresting day laborers at Home Depot. Meanwhile, Trump's threat to the Fed's independence could pose a real risk to the stability of the U.S. Plus, more on the shifting attitudes about Israel among Dems, the latest attack on Kyiv is another reminder of how much Putin is mocking Trump, and remembering Katrina 20 years later.

Sam Stein and the NYT's Talmon Smith join Tim Miller.