Science (Video)

Climate investor and philanthropist Tom Steyer, recipient of the 2025 Charles David Keeling Memorial Lecture, talks about the current and future state of energy. In a conversation with Scott Lewis of Voice of San Diego, Steyer argues that capitalism and policy must work together at scale, and highlights the marketplace rise of renewables like solar and EVs alongside challenges like slow fossil-plant retirement, grid constraints, and the need for longer-duration storage. He also discusses emerging options such as advanced geothermal and nuclear. The Keeling Memorial Lecure is given by a prominent member of the global change community able to speak on topics that reflect the legacy of Keeling's work. [Science] [Business] [Show ID: 41034]

The genome sequences of Neandertals and Denisovans have provided a wealth of new information about the origins, migrations, and interactions of ancient humans. These genomes have revealed that mixture between hominin groups was common: all modern humans outside Africa carry around 2% Neandertal DNA from a single major episode of Neandertal gene flow, while the ancestors of present-day Asians and Oceanians also met and mixed with multiple, genetically distinct Denisovan populations. Archaeological evidence suggests multiple dispersals of modern humans out of Africa, with early fossils identified in East and Southeast Asia over 50 thousand years ago. In contrast, genomic studies indicate that all present-day non-African populations descend primarily from a single dispersal after ~50 ka, though the migration routes of ancestral populations across Eurasia and Oceania remain unclear. Janet Kelso, professor at Max Planck Institute for Evolutionary Anthropology, shows how using the distribution of Neandertal and Denisovan ancestry in ancient and present-day modern humans can determine when, where and how often modern and archaic humans met and mixed. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41192]

An in vivo brain organoid platform reveals how human neurons and glia interact across development, aging, and disease. Fred H. Gage, Ph.D., generates three dimensional organoids from induced pluripotent stem cells and examines their maturation, synapses, and network activity with two-photon imaging and single-cell profiling. Gage integrates human microglia and astrocytes to study immune signaling, injury responses, and support functions that shape circuit behavior. Transplantation enables vascularization, reduces cell death, and yields features consistent with a blood brain barrier. Analyses identify diverse astrocyte types and trajectories, while patterns of tau expression inform Alzheimer’s disease modeling. Gage also converts adult fibroblasts into age retaining neurons that assemble into 3D spheroids, creating complementary models to connect genes, cells, and circuits with pathology and to guide strategies for prevention and therapy. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41160]

It is well known that inside nearly every living cell on this planet, there are instructions powering the dynamics of everything in the cell, known as deoxyribonucleic acid (DNA). Enoch Yeung, Associate Professor of Mechanical Engineering at UC, Santa Barbara, explains how DNA is the genetic code that tells cells where to live, how to live, and how to adapt when things get tough. Editing DNA has unlocked new potential in biology, enabled new therapeutics, diagnostics, and modes of treating diseases. Since DNA is double-stranded, it literally maintains a backup copy of itself to proof-read and facilitate stability of code. The double-stranded nature of DNA also means it can sometimes encode two messages in a given length! In short, DNA is amazing. Series: "GRIT Talks" [Science] [Show ID: 41040]

Clinical trials turn scientific discoveries into real options for patients and volunteers, advancing care while safeguarding participants. Sheldon Morris, M.D., M.P.H., explains how independent oversight, core ethical principles, and stepwise phases evaluate safety and benefit, and clarifies participants’ rights and responsibilities. Sandip Patel, M.D., F.A.S.C.O., highlights how carefully designed studies open access to promising cell and gene-based approaches while balancing risks and benefits. Robert A.J. Signer, Ph.D., underscores why participation—including consenting to share samples and data—helps researchers understand disease and accelerate better treatments. Morris, Patel, and Signer point audiences to practical ways to locate studies through registries and national databases, discuss what costs are typically covered, and advise asking questions about study design and safety. They also caution against unproven “stem cell tourism” and emphasize informed decisions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40438]

Nature has been running chemistry experiments for over 4 billion years—yet today, much of modern organic chemistry still depends on wasteful, resource-heavy methods that rely on oil-based solvents. These solvents aren’t recycled, and when burned, they release CO2, adding to climate change. But what if chemistry could be done differently? Bruce Lipshutz, Distinguished Professor of Chemistry at UC Santa Barbara, shows how it’s possible to carry out organic reactions in water—nature’s own solvent. His research demonstrates that chemistry in water isn’t just more sustainable, it can also be faster, cheaper, and more effective than traditional approaches. Series: "GRIT Talks" [Science] [Show ID: 41029]

We’re surrounded by digital devices—from phones and tablets to streaming platforms and social media. With so many options at our fingertips, each of us faces choices about when and how to use technology in ways that align with our goals and values. In this talk, Kristy Hamilton, Assistant Professor in the Department of Communication at UCSB, shares research on how digital media shapes the way we see ourselves and, in turn, influences our everyday technology use. Hamilton uses experimental methods to study the strengths and challenges of human memory and cognition in digital environments, with the aim of helping people become more effective thinkers in today’s media landscape. Series: "GRIT Talks" [Science] [Show ID: 41030]

What does it really mean to go zero waste? At UC Davis, the answer is both innovative and inspiring.

Episode 4 of ‘Sustainably UC Davis’ explores how the university is moving toward a zero-waste future—from converting campus food scraps into renewable energy, to phasing out single-use plastics in food service. Featured in the episode are Joseph Yonkoski, Facilities Management superintendent of thermal infrastructure and former READ facility supervisor, Kelli O’Day, UC Davis Sustainability Assessment Program Manager, and Zero Waste Student Coordinators Grae Mordhorst and Sophie Fayet-Faber. Series: "UC Davis News" [Public Affairs] [Science] [Show ID: 41059]

Wine down with Chancellor May as he meets up with some of the students, staff and faculty from the Department of Viticulture and Enology — recognized as one of the best programs in the world. Chancellor May tours the winery and vineyard, learns about the winery's cutting-edge technology and sustainability practices, and even helps crush grapes before sampling the final product with his "partner in wine." Series: "UC Davis News" [Public Affairs] [Science] [Show ID: 41062]

Batteries have become an essential component of our daily life. They power our smartphones, laptops, tablets, and many of the cars around us. They are also key to the renewable energy transition. Building better batteries requires the design of materials whose chemical composition and structure evolve drastically on charge and discharge, yet those changes must be perfectly reversible for the device to sustain hundreds or thousands of charge-discharge cycles. Raphaële Clément, Associate Professor of Materials Department at UC Santa Barbara, explains why this is a challenging task that necessitates an atomic-level understanding of the inner workings of battery materials. Clément is working to establish materials design rules and optimize materials processing approaches to advance electrochemical energy storage. Series: "GRIT Talks" [Science] [Show ID: 41031]