This week, we dive headfirst into the holiday madness: the fine art of pretending things can wait till January, how stuffing a week's worth of chaos into three days is our new normal, and why Thanksgiving is synonymous with "eating a regrettable amount of food" (parades optional).

But don't worry, we're not just here for turkey talk. We rip into site centricity (is it more than branding?), the never-ending sponsor/CRO shuffle, and why clinical research still can't figure out standardization to save its life. Private equity's creeping fingers? NIH funding's real impact? Fragmented systems that would drive anyone to drink? Yep, it's all in here.

We even tackle the million-dollar question: is there a user-friendly, centralized home for finding trials? (Spoiler: "No.") Plus, anecdotes, Reddit gems, and a little healthy skepticism about the "synergies" of consolidation.

Got thoughts, rants, or industry beef? Drop us a line at notetofilepodcast.com. Subscribe, listen, and join the conversation as we pull no punches and keep clinical research as weird - and real - as it deserves to be.