With updated thyroid cancer guidelines, adjunct diagnostic and treatment tools, and growing interest in minimalist approaches, it is increasingly challenging to know the optimal management for patients with small, differentiated thyroid cancer including when to refrain from operating. In this episode, we discuss the nuanced decision making in managing these patients, the multiple factors that are taken into consideration, and strategies in conducting efficacious conversations with patients. Hear from our world-renowned expert panel, Dr. Michael Tuttle, Professor and Chief of Endocrinology at Memorial Sloan Kettering Cancer Center, and Dr. Douglas Fraker, The Jonathan Rhoads Professor of Surgery Emeritus at the University of Pennsylvania , moderated by Dr. Mahsa Javid, Endowed Chair in Endocrine Surgery.