Inevitable

Startup Series: Epoch Biodesign


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Today's guest is Jacob Nathan, CEO and Co-Founder of Epoch Biodesign.

Plastics are among the most visible and ubiquitous environmental issues plaguing Earth today. Hundreds of millions of tons of plastics are produced every year, but they weren't mass produced until after World War II (that's just one human lifetime ago). As a byproduct of the fossil fuel industry, plastics contribute significantly to the value of a barrel of oil, they create considerable emissions when produced, and they release carbon into the atmosphere when they are incinerated at the end of their lifecycle. So while plastics are a key building block of our modern world, they're also very problematic. 

Epoch Biodesign is on a mission to scale and industrialize biology to solve the world's biggest climate challenges, starting with an enzyme that eats plastic and converts it to industrial chemicals. The company is currently working with unrecyclable plastics that would otherwise go to landfill or incineration. The resulting molecules from their unique biological process can be used to create new products like adhesives, cleaning products, and fertilizers. 

In today’s episode, we cover: 

  • An overview of plastics, their origin, widespread uses, and impacts on the environment
  • Plastics and the fossil fuel industry
  • Problems associated with recycling 
  • End of life pathways most plastics take 
  • Epoch Biodesign's solution to addressing the plastic problem 
  • How enzymes can break down plastics and convert them into useful chemicals with a reduced carbon footprint 
  • The company's cell-free fermentation process and target outputs 
  • CO2 emissions associated with producing and incinerating plastic chemicals 
  • The origin of Epoch Biodesign 
  • Jacob's background and how he met his Co-Founder, Douglas Kell 
  • Douglas Kell's extensive background in systems biology, machine learning, etc. 
  • How Epoch Biodesign uses machine learning and tooling to design a computing platform for plastic-eating enzymes 
  • Future applications of the company's proprietary methods of designing biology 
  • How Epoch Biodesign's software enables them to scale and solve climate problems faster
  • The company's business model 
  • Adjacent opportunities including textiles 
  • Epoch Biodesign's seed round and future financing 
  • Who Jacob wants to hear from and open positions at Epoch Biodesign

Enjoy the show!

You can find Cody on Twitter @codysimms, @mcjpod (podcast) or @mcjcollective (company). You can reach us via email at [email protected], where we encourage you to share your feedback on episodes and suggestions for future topics or guests.

Episode recorded July 15, 2022.

Enjoyed this episode? Please leave us a review! Share feedback or suggest future topics and guests at [email protected].

Connect with MCJ:

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*Editing and post-production work for this episode was provided by The Podcast Consultant

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