Can real-time EHR–generated recommendations safely reduce antibiotic use in hospitalized patients with pneumonia or UTI? Shruti K. Gohil, MD, MPH, of the University of California-Irvine, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss the INSPIRE randomized clinical trial. Related Content:

• Stewardship Prompts to Improve Antibiotic Selection for Pneumonia
• Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection
• Harnessing the Electronic Health Record to Improve Empiric Antibiotic Prescribing