Three prestigious surgeons on three continents provided their “Personal Reflections from COVID-19” during the STS Annual Meeting Thomas B. Ferguson Lecture. The surgeons shared their experiences and thoughts about the pandemic and how it has affected them, their families, institutions, colleagues, and their patients. Craig R. Smith Jr., MD, offered his view from Columbia University and NewYork-Presbyterian Hospital in New York City, Enrico Ruffini, MD, provided his perspective from the University of Torino in Italy, and Alan D.L. Sihoe, MD, MA, FRCSEd, described his experiences at Gleneagles Hospital in Hong Kong—an area that was the epicenter of the horrific SARS outbreak in 2003.