In this episode of the STS Webinar Series, Joseph E. Bavaria, MD, and an expert panel engage in a lively and robust debate on takeaways from three recent and very prominent adult cardiac surgery manuscripts. Topics include findings from the ISCHEMIA trial, 2-year outcomes in low-risk transcatheter aortic valve replacement patients, and a new guideline on the timing and intervention for patients with valvular heart disease. Panelists include Anelechi C. Anyanwu, MD, MSc, FRCS, Pavan Atluri, MD, Steven F. Bolling, MD, David A. Fullerton, MD, Katherine Harrington, MD, Marc Ruel, MD, MPH, FRCSC, and Vinod H. Thourani, MD.