In the latest episode of the STS Webinar Series, a panel of infectious disease, cardiology, and cardiothoracic surgery experts discusses findings and recommendations from a new guidance statement on perioperative vaccination for CT surgery patients. They offer personal experiences and advice on administering the COVID vaccine in the perioperative period, potential adverse effects, and considerations for booster shots. Participants include Mara B. Antonoff, MD, David M. Aronoff, MD, Rakesh C. Arora, MD, PhD (moderator), Adam F. Burdorf, DO, Daniel T. Engelman, MD, and HelenMari L. Merritt-Genore, DO (moderator).