The After the Bell Podcast

Most people know about BRCA1 and BRCA2…

But what about the other gene mutations that increase breast cancer risk and could shape your treatment and prevention plan?

In this video, I’m breaking down two under-recognized but important players:

🔬 CHEK2: an inherited genetic mutation that affects DNA repair and raises the risk for breast, colon, and prostate cancer

🧬 PIK3CA: an acquired mutation found in up to 40% of HR-positive, HER2-negative breast cancers, now guiding the use of new targeted therapies

If you’ve had breast cancer, have a family history, or want to understand your genetic testing results, this is a must-watch.

You'll also learn how to support your body even with mutations with functional and lifestyle strategies.

📌 Topics covered:

• Germline vs somatic mutations

• CHEK2 mutation symptoms & risk

• PIK3CA and the latest treatment advances

• How to reduce cancer risk naturally—even with mutations

• Why genetic testing panels should go beyond BRCA

🔗 Sources referenced:

• https://ascopost.com/news/may-2025/inavolisib-based-regimen-in-pik3ca-mutated-hr-positive-her2-negative-advanced-breast-cancer/

• https://today.ucsd.edu/story/to-study-cancer-kill-switch-uc-san-diego-scientists-will-send-stem-cells-to-space

• https://vhio.net/2025/05/31/triplet-combination-as-a-new-treatment-option-in-pik3ca-mutated-locally-advanced-or-metastatic-breast-cancer

• https://pubmed.ncbi.nlm.nih.gov/22058428/

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DISCLAIMER: This is not medical advice. The information provided is for informational and educational purposes only. It does not substitute for professional medical advice. It is not intended to diagnose or treat any physical or psychological health condition.

These are my own opinions from my own experiences.

Links above are affiliate links. This means I receive a commission through purchases. This does not affect you as a consumer.

You rang the bell… but now what?

In this video, I’m opening up about the truth behind cancer survivorship and why the hardest part can start after treatment ends.

I created “After the Bell” to fill the gap so many of us feel when we’re told we’re done… but we’re still exhausted, lost, and trying to rebuild.

If you’re navigating life after cancer, medical menopause, or just trying to feel like yourself again, you’re not alone. This is for you. 💛

Start Healing ➡️ https://www.afterthebellhealing.com

Follow me & say hi!

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DISCLAIMER: This is not medical advice. The information provided is for informational and educational purposes only. It does not substitute for professional medical advice. It is not intended to diagnose or treat any physical or psychological health condition. These are my own opinions from my own experiences.

#breastcancer #breastcancerawareness #breastcancercare

Struggling with weight, fatigue, or recovery after cancer or in menopause? Here’s why protein is key - and how to get enough without the overwhelm. In today’s video, I’m breaking down why protein is a non-negotiable when it comes to fat loss, recovery, and energy after breast cancer and in forced menopause. We’ll cover how much protein you actually need, when to eat it, and how it supports your metabolism, hormones, and healing. Whether you're a survivor navigating post-treatment life or in the thick of menopause symptoms, this is your guide to using nutrition as a tool, not a punishment. RECIPE FREEBIE https://laurencranmer.myflodesk.com/proteinforward CONNECT WITH ME Instagram www.instagram.com/laurenmcranmer   Website: www afterthebellhealing.com VIDEO DETAILS vlog camera: https://amzn.to/3XnFQme  DISCLAIMER: This is not medical advice. The information provided is for informational and educational purposes only. It does not substitute for professional medical advice. It is not intended to diagnose or treat any physical or psychological health condition. These are my own opinions from my own experiences. #forcedmenopause #breastcancersurvivor #menopauseweightloss #proteinforwomen #afterthebellpodcast

Forced menopause can feel like an uphill battle especially when it comes to fat loss, energy, and confidence. This series gives you the tools to understand your changing body, master your metabolism, and build a lifestyle that supports lasting health and strength. You’re not alone, and together, we’ll thrive.

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DISCLAIMER: This is not medical advice. The information provided is for informational and educational purposes only. It does not substitute for professional medical advice. It is not intended to diagnose or treat any physical or psychological health condition. These are my own opinions from my own experiences. Links above are affiliate links. This means I receive a commission through purchases. This does not affect you as a consumer. #menopauseafterbreastcancer #breastcancerawareness #breastcancercare

This week on🎙️After the Bell Podcast ➡️ we Devon Fanelli, PT, DPT, CLT. Devon is a Breast Cancer Rehabilitation Therapist and Certified Lymphedema Therapist and is passionate about providing quality care to women who are experiencing cancer treatment. In this episode, we dive deep into understanding lymphedema - what it is, how it happens, prevention, how to deal with it and much more. After the Bell is a podcast for cancer thrivers sharing cancer stories, advice, and hope. We are all in this together. Connect with Devon ⬇️ [email protected]

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After the Bell is a podcast for cancer thrivers where we share cancer stories, advice, and hope. We are all in this together. This week on🎙️After the Bell Podcast ➡️ we have Kate Ellis. Kate has experienced breast cancer three times and is still undergoing active treatment. She shares her unique story to shed light on the importance of advocating for yourself. Find Kate on IG http://www.instagram.com/lump_into_lemonade Links www.knowyourlemons.org 🎙️ After the Bell | a podcast for cancer thrivers Available on YouTube | Spotify | Apple Make sure to SUBSCRIBE to make sure you don't miss it! 👥🎙️DO YOU WANT TO BE A GUEST AND SHARE YOUR STORY? 🎥 Apply here: https://forms.gle/deExC4ppbhKX12DS8 ------------------------------------------------------------- Let's connect! IG https://www.instagram.com/laurenmcranmer ✉️ [email protected] www.afterthebellhealing.com 💖 ------------------------------------------------------------- VIDEO DETAILS // vlog camera: https://amzn.to/3XnFQme Free Music for Videos 👉 Music by Kris Cari- Invoca - https://thmatc.co/?l=FEDFA81E