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Host Kevin Patton walks listeners through three warnings he gives in his course syllabus, plus the safety advice he always includes. Updates on HAPS travel awards, including a brand new one! Don't forget Preview episodes & the Nuzzel newsletter.
00:46 | Nuzzel Newsletter 01:50 | Sponsored by HAPS 02:18 | HAPS Travel Awards 13:06 | Sponsored by AAA 13:28 | Preview Episodes 15:59 | Syllabus Warnings 32:19 | Sponsored by HAPI Online Graduate Program 32:51 | Safety Advice 53:45 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Here's something I've heard said of being a nurse: "Where else can you experience the thrill of having total strangers poop in front of you like it's totally your business?" (Anonymous)
Nuzzel Newsletter
1 minute
Nuzzel is a service that allows a curator to select daily headlines trending in social media and publish them as an email newsletter. In the Nuzzel for The A&P Professor, host Kevin Patton selects daily headlines that may be of interest to anatomy and/or physiology faculty. This Nuzzel newsletter is published five days a week (more or less).
To check out the archives of past Nuzzel newsletters, or to subscribe, go to: nuzzel.com/theAPprofessor
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Anatomy & Physiology Society
theAPprofessor.org/haps
g HAPS Travel Awards11 minutes
Sometimes it's hard to make it to a conference that we really want to attend because we just can't pull together the financial resources. With HAPS travel awards, that just got a lot easier!
Go to theAPprofessor.org/haps NOW (yes, I"m shouting) so that you can pull your application together in plenty of time for the January 3 deadline!
Sponsored by AAA0.5 minutes
A searchable transcript for this episode, as well as the captioned audiogram of this episode, are sponsored by the American Association for Anatomy (AAA) at anatomy.org.
Searchable transcript
Captioned audiogram
Preview Episodes
2.5 minutes
If you're not listening to the preview episodes that precede each full episode (like this one), you're missing out on a lot!
Each preview usually has these features:
But wait! There's more! Sometimes. Like in the preview episode for this full episode, there's a segment all about the features of the free TAPP app and Kevin plays a clip from a recent audio/video review of this podcast by podcasting experts.
Syllabus Warnings
16.5 minutes
Kevin usually has a Warnings! page in his syllabus or other course documents. It contains three warnings about, and rationale explaining, some important things a student should know before continuing in the A&P course. There is shouting involved.
Sponsored by HAPI Online Graduate Program
1 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
nycc.edu/hapi
Safety Advice21 minutes
We're held responsible (at least in part) for the safety of everyone in our classroom. How best to prepare for and facilitate safety?
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Tools & Resources Amazon TextExpander Rev.com Snagit & Camtasia The A&P Professor Logo Items Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
A brief preview of the upcoming full episode, featuring upcoming topics—plus word dissections, a book club recommendation of Powerful Teaching: Unleash the Science of Learning, an external review of this podcast, and the TAPP app!
00:19 | Topics 01:49 | TAPP app 13:24 | Podcast Review Show 17:25 | Sponsored by HAPI Online Graduate Program 18:05 | Word Dissection 21:54 | Sponsored by HAPS 22:15 | Book Club 25:58 | Sponsored by AAA 26:13 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Upcoming Topics1.5 minute
11.5 minutes
4 minutes
0.5 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
4 minutes
Syllabuses or syllabi, which is it?
(retake of a classic segment from: 49 MORE Tricks for Retention & Success in Online Courses | Episode 22)
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
3.5 minutes
0.5 minutes
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Tools & Resources Amazon TextExpander Rev.com Snagit & Camtasia The A&P Professor Logo Items Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
Revisiting an earlier discussion of his hard-line stance on misspelling, host Kevin Patton clarifies the history and context of his current strategy. Plus updates on macrophages that line joints and sugar-coated RNA —and tips on safely labeling our lab models.
00:48 | glycoRNA 06:45 | Sponsored by HAPS 07:15 | Barrier Macrophages 18:17 | Sponsored by AAA 18:37 | Labeling Lab Models 32:33 | Sponsored by HAPI Online Graduate Program 33:08 | More on Spelling 49:33 | Share the Fun! 50:27 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
"Failure is instructive. The person who really thinks learns quite as much from his failures as from his successes." (John Dewey)
glycoRNA6 minutes
Yep, yet another form of RNA has been discovered. This "sugar-coated" RNA is a small, noncoding RNA called Y RNA that has been glycosylated with an N-glycan. What do glycoRNAs do? What does that mean? Listen and learn.
Credit: Ryan A. Flynn/bioRxiv[
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Anatomy & Physiology Society
theAPprofessor.org/haps
Barrier Macrophages11 minutes
We knew there were macrophages within, and upon, the synovial membrane that lines synovial joints. What we have just learned is that macrophages on the synovial membrane surface can bind with tight junctions to form a barrier layer. Go figure.
0.5 minutes
A searchable transcript for this episode, as well as the captioned audiogram of this episode, are sponsored by the American Association for Anatomy (AAA) at anatomy.org.
Searchable transcript
Captioned audiogram
Labeling Lab Models
14 minutes
Kathryn Chipchase is concerned about damaging her new anatomical models when labeling them with lab tape for practical tests. So Kevin does some research. Listen to the results of his search. Oh, and find out the first rule of Tape Club, too!
Sponsored by HAPI Online Graduate Program
1 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
nycc.edu/hapi
More on Spelling, Case, & Grammar16.5 minutes
Sometimes a student frets about the A&P course being "not a spelling course" or "not an English course" — but professional communication is an essential skill for health professionals. Why not add this statement to our syllabus and/or other course documents?
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Tools & Resources Amazon TextExpander Rev.com Snagit & Camtasia The A&P Professor Logo Items Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
A brief preview of the upcoming full episode, featuring upcoming topics (macrophages in joints, sugared RNA, lab models, and more on scoring misspellings)—plus word dissections, a book club recommendation (The Miniature Guide to Critical Thinking Concepts and Tools), and more!
00:19 | Topics 01:24 | Sponsored by HAPI Online Graduate Program 01:53 | Word Dissection 18:36 | Sponsored by HAPS 18:57 | Book Club 21:00 | Sponsored by AAA 21:16 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Upcoming Topics1 minute
0.5 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
16.5 minutes
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
2 minutes
0.5 minutes
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Tools & Resources Amazon TextExpander Rev.com Snagit & Camtasia The A&P Professor Logo Items Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
Host Kevin Patton discusses the importance of teaching proper communication in the anatomy & physiology course. Topics include handling spelling errors, alternate spellings, proper use of type case, and addressing professionalism goals in the syllabus.
00:47 | Is Spelling Important? 10:06 | Sponsored by HAPS 10:33 | Alternate Spellings 14:12 | Sponsored by AAA 14:31 | A Case for Proper Case 26:16 | Sponsored by HAPI Online Graduate Program 27:05 | Professionalism as a Course Goal 30:05 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
When our spelling is perfect, it's invisible. But when it's flawed, it prompts strong negative associations. (Marilyn vos Savant)
Is Spelling Important?
9.5 minutes
I've done a complete turnaround in my teaching over the years —I used to be lenient about correct spelling, but now I'm a stickler for exactly correct spelling. In this segment I discuss my reasons.
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Anatomy & Physiology Society
theAPprofessor.org/haps
Alternate Spellings
3.5 minutes
Some terms can be correctly spelled more than one way. There is also an issue of differences in spelling from one dialect of English to another (e.g., U.K. English compared to U.S. English). If we are to expect our students to use correct spelling, we have to keep up with acceptable variations.
Sponsored by AAA
0.5 minutes
A searchable transcript for this episode, as well as the captioned audiogram of this episode, are sponsored by the American Association for Anatomy (AAA) at anatomy.org.
Searchable transcript
Captioned audiogram
A Case for Proper Case
11.5 minutes
When we properly capitalize terms, it demonstrates our professionalism, serves as a teaching model for students, improves clarity, and potentially reduces medical errors. A capital idea!
Sponsored by HAPI Online Graduate Program
1 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
nycc.edu/hapi
Professionalism as a Course Goal
3 minutes
Sometimes a student frets about the A&P course being "not a spelling course" or "not an English course" — but professional communication is an essential skill for health professionals. Why not add this statement to our syllabus and/or other course documents?
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Referrals also help defray podcasting expenses. Amazon TextExpander Snagit & Camtasia The A&P Professor Logo Items Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
A brief preview of the upcoming full episode, featuring upcoming topics—mostly about whether proper spelling and letter case is important in teaching A&P—plus word dissections, a book club recommendation of Endurance: My Year in Space, A Lifetime of Discovery, and more!
00:19 | Topics 01:45 | Sponsored by HAPI Online Graduate Program 02:29 | Word Dissection 16:07 | Sponsored by HAPS 16:34 | Book Club 19:52 | Sponsored by AAA 20:14 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Upcoming Topics
1.5 minutes
Sponsored by HAPI Online Graduate Program
0.5 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
Word Dissections
13.5 minutes
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Book Club
3.5 minutes
Sponsored by AAA
0.5 minutes
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Referrals also help defray podcasting expenses. Amazon TextExpander Snagit & Camtasia The A&P Professor Logo Items Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
Host Kevin Patton previews the newly revised HAPS Learning Outcomes for A&P, discussing the goals of the revision and samples a few of the changes. Why is noon a good time to get your flu shot? Are there neurons that actively erase memories? Vaping: why A&P teachers need to keep up with the news.
00:42 | Timing of Vaccinations 02:36 | Sponsored by HAPS 03:04 | Neurons That Erase Memory 08:22 | Sponsored by AAA 08:47 | Vaping 13:45 | Sponsored by HAPI Online Graduate Program 14:28 | Revisiting the HAPS Learning Outcomes for A&P 41:43 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
It is what we think we know already that often prevents us from learning. (Claude Bernard)
Timing of Vaccinations
2 minutes
With a new flu season upon us, vaccination is a timely topic. Recent research suggests that the time of day at which we receive our vaccination may influence it's effectiveness. At midday, CD8 T cells may respond more strongly than at other times of day.
Sponsored by HAPS
0.5 minute
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Neurons That Erase Memory
5.5 minutes
New evidence suggests that there is a population of neurons that actively erase old, unimportant memories during REM sleep. Hopefully, your memories of past episodes of this podcast will be preserved (as well as the date of my birthday).
Sponsored by AAA
0.5 minutes
Vaping
5 minutes
Vaping is a timely topic, considering the emergence of vaping-induced lung injury and other vaping-related conditions. Discussing the news about vaping, which is frequently updated, is appropriate in the A&P course. Following the story over the course of a year may helps students better understand human science.
Sponsored by HAPI Online Graduate Program
1 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
Revisting the A&P Learning Outcomes from HAPS
27 minutes
HAPS recently released its revised Learning Outcomes for A&P. It's a significant revision, with many improvements. Kevin discusses some of the changes and gives advice on how to navigate and use them in your course.
D: Histology
E: Integumentary System
F: Skeletal System & Articulations
G: Muscular System
H: Nervous System
I: General and Special Senses
J: Endocrine System
K: Cardiovascular System
L: Lymphatic system and immunity
M: Respiratory System
N: Digestive system
O: Nutrients & Metabolism
P: Urinary System
Q: Fluid/Electrolytes & Acid-Base Balance
R: Reproductive System
S: Introduction to Heredity
T: Embryology
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Referrals also help defray podcasting expenses. Amazon TextExpander Snagit & Camtasia The A&P Professor Logo Items Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
A brief preview of the upcoming full episode 54, featuring upcoming topics that include a brief discussion of the newly revised A&P Learning Outcomes from HAPS, updates regarding timing of vaccinations, a newly discovered type of neuron that erases old memories, and vaping.
There's more... some word dissections and Kevin's recommendation for The A&P Professor Book Club.
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Topics
2 minutes
Word Dissections
9.5 minutes
Book Club
5.5 minutes
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Referrals also help defray podcasting expenses. Amazon TextExpander Snagit & Camtasia The A&P Professor Logo Items Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
Host Kevin Patton summarizes the 2019 Nobel Prize in Physiology or Medicine to three scientists "for their discoveries of how cells sense and adapt to oxygen availability." A special bonus episode.
00:41 | Introduction to Bonus Episode 02:00 | Sponsored by HAPS 02:24 | Summary of Discovery 04:13 | Oxygen at Center Stage 05:24 | HIF Enters the Scene08:08 | Sponsored by AAA 08:26 | VHL - An Unexpected Partner 11:37 | Oxygen sHIFts the Balance 13:20 | Oxygen Shapes Physiology & Pathology 15:15 | Sponsored by HAPI Online Graduate Program 15:48 | Our Course 23:46 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Singing is like a celebration of oxygen. (Björk)
1 | Introduction to the Bonus Episode
1 minute
Kevin introduces the bonus episode, explaining that he's sharing the press release for the 2019 Nobel Prize in Physiology or Medicine. It's chunked for clarity.
Press release: The Nobel Prize in Physiology or Medicine 2019. NobelPrize.org. Nobel Media AB 2019. Mon. 7 Oct 2019. https://www.nobelprize.org/prizes/medicine/2019/press-release/>
2 | Sponsored by HAPS
2 minutes
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Anatomy & Physiology Society
theAPprofessor.org/haps
3 | Summary of the Discovery
2 minutes
4 | Oxygen at Center Stage
1 minute
During evolution, mechanisms developed to ensure a sufficient supply of oxygen to tissues and cells.
5 | HIF Enters the Scene
3 minutes
6 | Sponsored by AAA
0.5 minutes
7 | VHL - An Unexpected Partner
3 minutes
When oxygen levels are low (hypoxia), HIF-1α is protected from degradation and accumulates in the nucleus, where it associates with ARNT and binds to specific DNA sequences (HRE) in hypoxia-regulated genes (1). At normal oxygen levels, HIF-1α is rapidly degraded by the proteasome (2). Oxygen regulates the degradation process by the addition of hydroxyl groups (OH) to HIF-1α (3). The VHL protein can then recognize and form a complex with HIF-1α leading to its degradation in an oxygen-dependent manner (4). https://my-ap.us/35fm0O6
8 | Oxygen sHIFts the Balance
1.5 minutes
9 | Oxygen Shapes Physiology & Pathology
2 minutes
The awarded mechanism for oxygen sensing has fundamental importance in physiology, for example for our metabolism, immune response and ability to adapt to exercise. Many pathological processes are also affected. Intensive efforts are ongoing to develop new drugs that can either inhibit or activate the oxygen-regulated machinery for treatment of anemia, cancer and other diseases. https://my-ap.us/2LW2cIb
10 | Sponsored by HAPI Online Graduate Program1 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
nycc.edu/hapi
11 | Our Course
8 minutes
Semenza, G.L, Nejfelt, M.K., Chi, S.M. & Antonarakis, S.E. (1991). Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene. Proc Natl Acad Sci USA, 88, 5680-5684 my-ap.us/2ontmP8
Wang, G.L., Jiang, B.-H., Rue, E.A. & Semenza, G.L. (1995). Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA, 92, 5510-5514 my-ap.us/2IxLUD5
Maxwell, P.H., Wiesener, M.S., Chang, G.-W., Clifford, S.C., Vaux, E.C., Cockman, M.E., Wykoff, C.C., Pugh, C.W., Maher, E.R. & Ratcliffe, P.J. (1999). The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature, 399, 271-275 my-ap.us/2op4XbP
Mircea, I., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J.M., Lane, W.S. & Kaelin Jr., W.G. (2001) HIFa targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing. Science, 292, 464-468 my-ap.us/2IxIf8t
Jakkola, P., Mole, D.R., Tian, Y.-M., Wilson, M.I., Gielbert, J., Gaskell, S.J., von Kriegsheim, A., Heberstreit, H.F., Mukherji, M., Schofield, C.J., Maxwell, P.H., Pugh, C.W. & Ratcliffe, P.J. (2001). Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science, 292, 468-472 my-ap.us/35i4wR9
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Referrals also help defray podcasting expenses. Amazon TextExpander Snagit & Camtasia The A&P Professor Logo Items Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
Host Kevin Patton summarizes many strategies from learning science that can amplify learning in our courses. Also, updates in the role of exosomes in the spread of cancer and how activity type affects the shape of our heart.
00:48 | Jargon: Show Notes & Episode Pages 05:07 | Sponsored by HAPS 07:01 | Role of Exosomes in Spread of Cancer 13:20 | Sponsored by AAA 13:44 | Activity Type Affects Heart Shape 18:03 | Sponsored by HAPI Online Graduate Program 18:35 | Amplifying Learning in A&P: ANSWER 53:30 | Staying Connected
If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!
Give the pupils something to do, not something to learn; and the doing is of such a nature as to demand thinking; learning naturally results. (John Dewey)
1 | Jargon: Show Notes & Episode Page
4 minutes
Kevin explains that show notes are notes and links related to an episode.
You are reading the show notes right now!
The episode page is a page dedicated to an episode at theAPprofessor.org and it contains the show notes, which may also be available in the podcasts or radio app where you listen to episodes.
2 | Sponsored by HAPS
2 minutes
The Human Anatomy & Physiology Society (HAPS) is a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. There are a bunch of 1-day regional workshops scattered all over the continent. There's probably one near you coming up this year (or next)!
Anatomy & Physiology Society
theAPprofessor.org/haps
3 | Exosomes & Metastasis
6.5 minutes
Extracellular vesicles (EVs) such as exosomes and oncosomes play important roles in spreading cancer. For example, exosomes play a role in the metastasis of breast and lung cancer, through the blood-brain barrier (BBB) to the brain tissue. We are still working out the mechanisms.
4 | Sponsored by AAA
0.5 minutes
5 | Activity & Heart Shape
4.5 minutes
Evolution has played a role in making human hearts similar to chimpanzee hearts. The left ventricle is thick-walled and short—best suited for shorter and perhaps intense bursts of activity. However, the heart is able to elongate and have a thinner wall to adapt to a lifestyle that features endurance activity.
6 | Sponsored by HAPI Online Graduate Program
1 minute
The Master of Science in Human Anatomy & Physiology Instruction—the MS-HAPI—is a graduate program for A&P teachers. A combination of science courses (enough to qualify you to teach at the college level) and courses in contemporary instructional practice, this program helps you power up your teaching. Kevin Patton is a faculty member in this program. Check it out!
nycc.edu/hapi
7 | Amplifying Learning in A&P
35 minutes
In this discussion, Kevin borrows a mnemonic acronym from Yee and Boyd (cited below) that summarizes key strategies derived from learning science (cognitive psychology) and riffs on adapting it to the A&P course to amplify learning.
If the hyperlinks here are not active, go to TAPPradio.org to find the episode page.
Sponsors Transcript and captions for this episode are supported by the American Association for Anatomy. anatomy.org The Human Anatomy & Physiology Society also provides marketing support for this podcast. theAPprofessor.org/haps Distribution of this episode is supported by NYCC's online graduate program in Human Anatomy & Physiology Instruction (HAPI) nycc.edu/hapi Clicking on sponsor links helps let them know you appreciate their support of this podcast! Referrals also help defray podcasting expenses. Amazon TextExpander Snagit & Camtasia The A&P Professor Logo Items Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram! The A&P Professor® and Lion Den® are registered trademarks of Lion Den Inc. (Kevin Patton)
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