Summary

Dr. Tina Bhutani shares her journey to becoming a dermatologist and the challenges she faced along the way. She emphasizes the importance of being proactive in interviews and marketing oneself effectively. Dr. Bhutani also discusses the rewards and challenges of working in an academic setting, including the bureaucracy and administrative burdens. She highlights the significance of clinical trials and her interest in studying lifestyle modifications and their impact on skin disease. However, she acknowledges the difficulty of getting funding for these types of studies. In this conversation, she discusses her busy life as a dermatologist and the importance of patient-centered research and accessible clinical trials. Dr. Bhutani and Dr. Fara also talk about Dr. Bhutani's book that she co-authored on the use of biologics in psoriasis treatment. The conversation covers various chapters of the book, including laboratory monitoring, TNF-alpha inhibitors, IL-17 class of biologics, combination therapies, biologic agents for pediatric psoriasis, special site psoriasis, comparing biologic agents, long-term registry data, biologic agents in special populations, and adherence to biologic therapy. Dr. Fara and Dr. Bhutani emphasize the importance of individualizing treatment and having open conversations with patients about their preferences and needs.

Takeaways

• Be proactive in interviews and market yourself effectively

Chapters

00:00 Introduction and Background

08:39 Navigating the Challenges of an Academic Setting

29:27 The Value of TNF-alpha Inhibitors in Psoriatic Arthritis

36:04 Comparing Biologic Agents: Challenges and Considerations

Summary

In this episode, Dr. Farah Kamangar and Dr. Tina Bhutani discuss the challenges of accessing newer dermatology medications and the importance of proper documentation for prior authorization. They also touch on the use of patient coupons and the requirements set by insurance companies. The conversation highlights the need for clear and thorough notes, including previous treatments and failed therapies. The hosts emphasize the importance of advocating for patients and using all available resources to navigate the access process. They also discuss the potential role of AI in streamlining the prior authorization process.

This episode is sponsored by an educational grant from the company Dermavant.

Takeaways

• Accessing newer dermatology medications can be challenging due to the paperwork and prior authorization process.

Summary

In this episode, Dr. Farah Kamangar and Dr. Tina Bhutani discuss the efficacy and safety of Tapinarof, a non-steroidal topical therapy for psoriasis and atopic dermatitis. They highlight the impressive results of clinical trials, with 35-40% of psoriasis patients achieving clear or almost clear skin after 12 weeks of treatment. They also discuss the potential benefits of Tupinarof for atopic dermatitis patients. The side effects of folliculitis and headaches are mentioned, but overall, patients tolerate the medication well. The episode concludes with a discussion on the future of Tapinarof, including potential pediatric indications.

This episode is sponsored by an educational grant from the company Dermavant.

Takeaways

• Tapinarof is a non-steroidal topical therapy that has shown impressive efficacy in treating psoriasis, with 35-40% of patients achieving clear or almost clear skin after 12 weeks of treatment.

Summary

In this episode of the Future of Dermatology podcast, Dr. Farah Kamangar and Dr. Tina Bhutani discuss the mechanism of action of aryl hydrocarbon receptors (AHR) and its potential in dermatology. They explore the history of AHR and its connection to coal tar, as well as its role in inflammation, antioxidant activity, and metabolism. They also touch on the importance of considering the impact of circadian rhythms and sleep on skin health. The conversation highlights the potential of AHR-targeted therapies in achieving longer remissions and the need to view psoriasis patients as a whole, addressing comorbidities and environmental factors. The episode concludes with a discussion on the future of dermatology, including the possibility of directly targeting resident memory T cells and the further exploration of AHR mechanisms.

This episode is sponsored by an educational grant from the company Dermavant.

Takeaways

• Aryl hydrocarbon receptors (AHR) have a complex mechanism of action and can have anti-inflammatory, antioxidant, and metabolic effects.

Chapters

• 00:00 Introduction

Summary

In this follow up episode, Dr. Wilson Liao shares insights on the benefits of a research year for medical students and offers advice on transitioning back to medical school. He and SFDS Med Student, Chandler Johnson, also discuss the future of dermatology and the role of team science in advancing research.

Takeaways

• A research year provides medical students with valuable skills and insights into the field of dermatology.

Summary

In this episode, Dr. Wilson Liao discusses the genetics and environmental triggers of psoriasis. He highlights the significant progress made in identifying psoriasis genes and how they relate to the different types and severity of psoriasis. Dr. Liao also explores the connection between psoriasis genes and therapeutic response, as well as the potential for precision medicine in psoriasis treatment. The conversation delves into the evolutionary persistence of psoriasis and its survival advantage in fighting off viruses. The role of environmental triggers, such as obesity, diet, and smoking, is also examined. Additionally, Dr. Liao and Chandler Johnson discuss their current research studies, including the Skin Tracker Project and capillary blood testing. In this conversation, Dr. Wilson Liao and Chandler Johnson discuss various research projects and clinical trials in dermatology. They explore the use of RNA and proteins in research, the importance of studying multiple aspects of autoimmune disease, and ongoing psoriasis survey studies. They also delve into the impact of menopause on psoriasis and the relationship between sleep and psoriasis.

Takeaways

• Significant progress has been made in identifying over 100 psoriasis genes, which has led to a better understanding of the different types and severity of psoriasis.

Help us understand how psoriasis affects you

Help Us Understand More About Sleep and Psoriasis Are you interested in helping researchers understand how psoriasis and sleep are related?

Please consider taking our paid online survey. Recruiting both individuals with and without psoriasis. https://redcap.ucsf.edu/surveys/?s=RLFR379LNL4RFTTF

Help Us Understand About Menopause and Psoriasis Are you interested in helping researchers understand how psoriasis and menopause are related?

Please consider taking our paid online survey. Recruiting post-menopausal women with psoriasis. https://redcap.ucsf.edu/surveys/?s=JYTNX3XKDC84J3DX

Summary:

Dr. Keira Barr, MD, shares her non-traditional journey in dermatology and her focus on the mind-body connection in skin health. She discusses the harmful phrase "anti-aging" and the need to shift the conversation to a more positive and empowering approach. Dr. Barr also highlights the challenges and complexities of cosmetic dermatology consultations and the importance of addressing the psychological aspects of these procedures. She emphasizes the connection between mental health and skin health, particularly in relation to stress and trauma. Dr. Barr advocates for a more holistic and personalized approach to dermatology, incorporating mind-body techniques and personalized medicine. In this conversation, Dr. Keira Barr discusses the importance of skin health and provides insights into common skin conditions, prevention and treatment methods, and the role of skin care products. She also emphasizes the importance of skin cancer awareness and highlights the connection between skin health and overall well-being.

Takeaways:

• The phrase 'anti-aging' is harmful and should be replaced with a more positive and empowering approach to aging.

Learn more from Dr. Barr at:

Website: drkeirabarr.com

Skincare Quiz: yourskincarequiz.com

Podcast: The Skinny Dipping Rx: https://podcasts.apple.com/us/podcast/the-skinny-dipping-rx/id1635601527

Instagram: @drkeirabarr

Summary

In this episode, Dr. Farah Kamangar discusses the effects of alcohol on the skin. She highlights the importance of considering alcohol consumption as a potential factor in dermatological conditions such as rosacea, eczema, and psoriasis. Dr. Kamangar also explains the guidelines for alcohol consumption and emphasizes the need to follow them to maintain skin health. Additionally, she explores the impact of alcohol on the immune system and its contribution to skin aging.

Takeaways

• Alcohol consumption can lead to various skin conditions, including rosacea, eczema, and psoriasis.

Chapters

00:00

Introduction

00:32

Alcohol and its effects on the skin

03:14

Guidelines for alcohol consumption

04:10

Effects of alcohol on the skin

05:02

Alcohol and rosacea

06:28

Alcohol and other skin conditions

08:23

Alcohol and immune system

09:19

Alcohol and aging

09:49

Conclusion

Summary

In this episode of the Future of Dermatology Podcast, Dr. Faranak Kamangar discusses the shift from anti-aging to longevity in the field of dermatology. She explores the changing beauty standards and the desire to look more youthful and functionally enhanced. Dr. Kamangar also delves into the causes of aging, such as the fibroblast collapse theory, and the importance of behavioral changes and topical treatments for anti-aging. She highlights the role of retinoids in collagen production and introduces emerging therapies for anti-aging, including mTOR inhibitors and senolytics. The episode concludes with a discussion on the controversies surrounding the diagnosis of aging.

Takeaways

• The focus in dermatology has shifted from anti-aging to longevity and health span.

This podcast kicks off our anti-aging segment starting with Dr. Azadeh Shirazi, MD, FAAD, from More Than a Pretty Face Podcast, as she discusses her background, journey, and current practice in dermatology. Dr. Shirazi emphasizes the importance of social media and online education in connecting with patients and providing valuable information. She also shares her experience transitioning from a large corporate practice to opening her own private practice. She highlights the benefits of having a personalized, boutique practice and the challenges she has faced. Additionally, Dr. Shirazi talks about the creation of her skincare line and the comprehensive approach she takes in formulating her products.

Learn more at: https://azimdskincare.com/ Listen to Dr. Azi's podcast, More Than a Pretty Face, at https://morethanaprettyface.libsyn.com/