The S2G Podcast

The Future of Protein Through a Cross-Sector Lens


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When it comes to the future of protein, the stakes are pretty high. Protein sits at the center of the global food challenge, and innovating how we produce it is the key to sustainably feeding a growing population. Protein is also a massive, fast-evolving market where innovation and adaptation will drive the next wave of value creation. In our first “the seams” style episode of this season, S2G managing directors Matt Walker (Food & Ag), and Larsen Mettler (oceans), join Chuck Templeton to unpack the forces reshaping global protein production and consumption. They discuss surging demand, especially in seafood and poultry, structural supply chain risks from climate change and disease to cold-chain bottlenecks, and the opportunities in feed innovation, aquaculture, and plant-based and cultivated proteins. Drawing on cross-sector learnings from livestock breeding to AI-driven tools and full product utilization, Matt and Larsen share their visions for an abundant protein future where diverse systems work together to create a more resilient food supply chain.


Key takeaways:

1. Protein Demand Is Rising and Shifting: Larsen and Matt point out that global demand for protein is projected to grow 70% by 2050. In the U.S., growth is flattening, but consumption is shifting toward poultry as an affordable and efficient option. 

2. Supply Chains Are Under Increasing Pressure: Larsen speaks about how climate change, disease, and geopolitical shifts are exposing weak points in protein supply chains, from concentrated production to limited cold-chain infrastructure.

3. Feed Innovation Is Critical for Sustainability: Matt and Larsen share how new approaches, from algae-based oils to insect proteins, upcycling invasive species, and improving protein content of feed crops, are redefining how animals and fish are fed, reducing pressure on ecosystems.

4. Alternative Proteins Are Hitting Their Stride: Plant-based meat experienced hype but struggled with repeat customers. Now, companies are focusing on clean-label plant foods and hybrid approaches blending cultivated and plant-based products. 

5. Cross-Sector Collaboration Is Accelerating Innovation: Advances honed over decades in livestock, like better feed efficiency and stronger disease resistance, are now being applied in aquaculture. At the same time, cultivated meat and seafood companies are joining forces on regulatory approvals, while innovations in AI, feed, and full-product utilization are crossing sectors to build a more resilient and circular protein system.


This content is for informational purposes only, should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security, and is not directed at any investor or potential investor in any investment vehicle sponsored by S2G. Investing involves risk, including the risk of loss. Specific companies mentioned in this podcast are for educational purposes and should not be construed as an endorsement of any kind. S2G holds positions in the companies referenced, but this podcast is for information purposes only and is not intended to promote any such company. All views of the guests on this podcast are solely their opinions and do not reflect the opinions of S2G. Any past performance discussed is not indicative of future results. Chuck Templeton is a Managing Partner at S2G Investments. All Chuck's views, and the views of the guests on this podcast, are solely their opinions and do not necessarily reflect the opinions of S2G. The views expressed herein are opinions based on certain assumptions and subject to change.

For more important information, please see s2ginvestments.com/disclosures.

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