In this powerful and deeply personal episode, Parul Dua Makkar, BSc, DDS, FACD, shares how the loss of her younger brother, Manu Dua, DDS, to oral cancer changed the course of her life and career. Manu was a healthy, young dentist with few risk factors, yet his diagnosis came late — a reality that highlights the critical need for early detection and awareness. Dr. Makkar opens up about her brother’s story, the warning signs that were missed, and the emotional toll of watching a loved one navigate cancer. She also offers practical advice for healthcare providers on how to talk to patients about suspicious lesions, the importance of regular screenings, and the shifting demographics of oral cancer. Following Manu's death, she authored the book Life Interrupted: Dr. Dua's Survival Guide.

A passionate advocate, speaker, and award-winning author, Dr. Makkar is on a mission to educate both clinicians and the public about the importance of recognizing oral cancer risks—before it’s too late. She is a Board member American Academy of Oral Systemic Health and a Fellow for the American College of Dentists.