Dean Lloyd Minor welcomes Daphne Koller, PhD, founder and CEO of insitro, for a conversation about AI’s potential to transform drug discovery. They discuss how machine learning algorithms can accelerate the drug design process, quickly identifying biological patterns and predicting outcomes. They also explore the challenges and opportunities of founding a startup in Silicon Valley, and how insitro’s collaborations with large pharmaceutical companies are advancing therapeutics for Amyotrophic lateral sclerosis (ALS) and other conditions.

Dean Lloyd Minor welcomes Dr. Karen DeSalvo, Google’s Chief Health Officer, for a conversation about how AI can help inform and advocate for patients while supporting clinicians and increasing access to care around the world. They discuss AI tools that Google has developed to accelerate diagnostics, particularly in lower-resource areas, and they explore the potential for AI to serve as a personal health assistant for patients. They also discuss Google’s strategy for providing accurate, meaningful health information to the general public, and the challenges and opportunities of integrating AI technologies into clinical care.

Dean Lloyd Minor welcomes Meena Seshamani, MD, PhD, director of the federal Center for Medicare at the Centers for Medicare & Medicaid Services, for a conversation about supporting holistic health care through the country’s government insurance program for seniors. They discuss Medicare’s role in advancing prescription drug affordability and the importance of family caregivers and community workers in helping seniors attain their optimal health. They also explore practical approaches Medicare has deployed to advance health equity, and discuss what needs to be done to ensure the program’s financial strength and viability for generations to come.

Dean Lloyd Minor welcomes Michael Pfeffer, MD, chief information and digital officer at Stanford Health Care, and Nigam Shah, MBBS, PhD, the health system’s chief data scientist, for a conversation about how AI is being used to augment health care. They explore how AI is helping clinicians access troves of data to inform patient care and how it’s helping ease their clerical burden, allowing more time for meaningful interactions with patients. They also discuss the guardrails in place to protect privacy and ensure reliability, as well as what is needed to scale AI tools to benefit as many patients as possible.

Dean Lloyd Minor welcomes John Torous, MD, director of digital psychiatry at Beth Israel Deaconess Medical Center, for a conversation about AI’s potential to expand access to mental health care and enhance diagnosis and treatment. They discuss how AI can help detect mental distress from an individual’s digital footprint and how it can use data to inform personalized care plans. They also explore the promise and pitfalls of chatbots, how consumers can assess digital health tools, and how the mental health field is evolving to integrate digital health with in-person care — to the benefit of more patients. 

Dean Lloyd Minor welcomes Dr. Brian Anderson, co-founder and CEO of the Coalition for Health AI, for a conversation about guiding the responsible development and use of AI in health care. They discuss how government, technology companies, health systems, and patient groups are working together through CHAI to create standards for safe and effective AI tools. They also explore CHAI’s work to build a national network of quality assurance labs to test new AI technologies, and they discuss ways that medical education can prepare physicians of the future to leverage AI’s potential for the benefit of patients around the world.

Dean Lloyd Minor welcomes legendary musician Paul Simon for a conversation about his latest album “Seven Psalms,” and what it was like to lose hearing in his left ear as he was writing and recording it. In addition to Simon’s musical influences and songwriting process, they discuss his advocacy and involvement with the Stanford Institute to Cure Hearing Loss; and they explore Simon’s views on leadership and hopes for future medical advancements.

Dean Lloyd Minor welcomes Anne Wojcicki, CEO and co-founder of 23andMe, for a conversation about how personal genetics can empower consumers to drive healthier futures. They discuss how 23andMe has evolved over nearly two decades, including pioneering direct-to-consumer genetic testing. They also explore challenges and opportunities of partnering with health care providers, the potential for genetic data to elevate preventive health care, and how AI could accelerate innovation in medicine.

Dean Lloyd Minor welcomes violin virtuoso Itzhak Perlman for a conversation about the joy of performing, the importance of practice, and how musicians hone their unique sound. They discuss the nuances of teaching music, the connection between audience and performer, and how Perlman’s musical expression has changed over a career spanning six decades. They also explore some of Perlman’s most memorable performances, including at Barack Obama’s inauguration and performing Igor Stravinsky’s Concerto in D for the legendary composer.

Dean Lloyd Minor welcomes Carolyn Bertozzi, PhD, 2022 Nobel laureate in chemistry, professor of chemistry and director of Sarafan ChEM-H at Stanford University, for a conversation about her journey breaking barriers in scientific research. They discuss how her early passion for organic chemistry laid the foundation for her prize-winning work, and how the new field that she founded, bioorthogonal chemistry, has led to the development of better diagnostic testing and targeting for medical treatments. They also explore obstacles historically faced by women and LGBTQ scientists, the importance of fostering diversity in research labs, and how curiosity-driven discoveries can change lives for the better.