On this episode, we explore the stories of people who survived extraordinary trials, from life-threatening illnesses to assault, and ask what came after survival. We’ll hear what it’s like to survive — and come back from — locked-in syndrome, explore the emotional roller coaster of being a young cancer survivor, and find out how one writer created guide to intimacy after sexual assault.

More than a hundred thousand people in the U.S. are on the national transplant list waiting for a life-saving organ. Hospitals across the country transplant more than 45,000 organs each year and there are rules and protocols about how it is supposed to go. But what happens when the process fails?

The New York Times investigative reporter Brian Rosenthal joins us to discuss some recent cases where doctors discovered that patients were still alive and conscious when the donation process was underway. He talks with host Maiken Scott about a relatively new method of procuring organs, called circulatory death donation, and new pressures on procurement organizations that could be jeopardizing safety.

Rosenthal and his colleague Julie Tate recently published an investigation in The New York Times called, “A Push for More Organ Transplants Is Putting Donors at Risk.”

Shame has a way of making us feel alone — like we’re the only ones in the world struggling with something. It can make us withdraw or feel depressed, out of control, and helpless. In the worst cases, it can destroy our self-esteem and even lead to self harm. But shame can also be a force for positive change, from enforcing social norms, to pushing us to improve our behaviors and circumstances. 

On this episode, we untangle why we feel it, where shame comes from, and how it affects our behavior and health. Lots of us have hangups about what we look like in swimsuits — but wait until you hear about what “kind of attire” used to be acceptable at pools. We’ll explore the evolutionary roots of shame, how one woman discovered what was behind her monthly meltdowns, and how shame figures into treatment approaches in the opioid epidemic.

What comes to mind when you think of the ocean? Maybe a day at the beach — swimming in the waves, snorkeling through coral reefs, fishing, surfing, and sunsets that kiss the blue horizon. But Earth’s oceans are more than that; they’re our planet’s defining feature, its largest ecosystem, and the original source of all life. On this encore episode, we explore the engine that powers our planet.

We often think of sleep as the gas that keeps us running. We refuel at night — or whenever we can — run around all day until our tanks are empty, and then do it all over again the next day. But some sleep scientists would like us to think about sleep less as fuel, and more as a biological rhythm — one that’s as essential to our overall health as our heartbeat. On this episode, we’ll explore how finding your body’s unique sleep rhythm can help you get better rest.

We’ve only been able to harness the cold for our benefit for a little over 100 years, but innovations like refrigeration and air conditioning have completely transformed the way we live and eat. But it all comes at a cost — and not just financially. On this encore episode, how advances in cold technology have shaped our lives and changed the world. 

Twenty-five years ago, President Bill Clinton announced a historic achievement: The completion of the first-ever survey of the human genome. The ceremony focused on the power of unity and collaboration — but, behind the scenes, the journey to this generational discovery had been marked by a bitter, cut-throat competition. We  look back at the race to decode the human genome — and who really won.

Friends make us laugh, they have our back, we share memories and stories. Beyond that, scientists are learning that friendships are key in keeping us healthy and thriving. On this episode, we explore why researchers say our brains are wired for connection, and why making our friendships a priority is one of the key pillars of longevity. We’ll get some research-backed advice on making new friends as adults and hear from two friends who love spending time with each other, though they usually can’t remember their adventures.

When someone wrongs us, getting revenge can feel like the only right move — the only way for us to balance the scales, to set the world right again. But the consequences can be disastrous, especially when payback becomes an all-consuming obsession. 

On this episode, we talk with lawyer-turned-researcher James Kimmel about his new book, "The Science of Revenge: Understanding the World's Deadliest Addiction — and How to Overcome It." We discuss the evolutionary roots of revenge, the neuroscience behind why it feels so good, and how Kimmel eventually traded vengeance for forgiveness. We also find out what caused a murder of crows to target an unsuspecting woman, and what was behind their years-long grudge.

Creativity plays a role in every facet of our lives, from childhood education, to everyday problem-solving, to the artistic works we enjoy and the innovations shaping our future. We explore what human creativity is, how it works, and some of the unexpected ways it’s remaking our world.