Professors Sahel and Roska describe partial visual recovery of a patient with advanced RP using optogenetic technology.

Discussed article:

Sahel JA, Boulanger-Scemama E, Pagot C, Arleo A, Galluppi F, Martel JN, Esposti SD, Delaux A, de Saint Aubert JB, de Montleau C, Gutman E, Audo I, Duebel J, Picaud S, Dalkara D, Blouin L, Taiel M, Roska B. Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med. 2021 Jul;27(7):1223-1229. doi: 10.1038/s41591-021-01351-4. Epub 2021 May 24. PMID: 34031601.

Dr. Seider elaborates on his group's large retrospective study on rates and risk factors for complicated acute posterior vitreous detachment.

Full reference to the discussed article:

Seider MI, Conell C, Melles RB. Complications of Acute Posterior Vitreous Detachment. Ophthalmology. 2021 Jul 27:S0161-6420(21)00552-2. doi: 10.1016/j.ophtha.2021.07.020. Epub ahead of print. PMID: 34324945.

Dr. Tina Felfeli discusses 3 articles around COVID-19 and ophthalmology: (1) Effect of various concretions and exposure times of common ophthalmology anti-septics on COVID-19 infected cell lines. (2) Effect of the pandemic on the backlog of elective ophthalmic surgical cases in the province of Ontario, Canada (3) Detection of the COVID-19 virus in different ocular tissues of a patient that tested positive for COVID-19.

Referenced articles:

1. Felfeli T, Kasloff SB, Krishnan J, El-Defrawy SR, Mazzulli T, Cutts TA. In vitro efficacy of topical ophthalmic antiseptics against SARS-CoV-2. BMJ Open Ophthalmol. 2021 Jun 9;6(1):e000765. doi: 10.1136/bmjophth-2021-000765. PMID: 34192157; PMCID: PMC8190983.
2. Predicting the Ophthalmic Surgical Backlog as a Result of the COVID-19 Pandemic: A population-based study and microsimulation model to inform surgical recovery plans Tina Felfeli, Raphael Ximenes, David MJ Naimark, Philip L Hooper, Robert J Campbell, Sherif R El-Defrawy, Beate Sander, the COVID-19 Mod Collab medRxiv 2021.03.25.21254375; doi:https://doi.org/10.1101/2021.03.25.21254375
3. Felfeli T, Mazzulli T, Clark ST, El-Defrawy SR, Chan CC. SARS-CoV-2 Not Detectable in Ocular Specimens of a Patient with a Past Infection. Ocul Immunol Inflamm. 2021 Apr 7:1-3. doi: 10.1080/09273948.2021.1894458. Epub ahead of print. PMID: 33826479.

Dr. Almeida presents a mathematical model based on Newtonian mechanics to discuss vision recovery of different anti-VEGF medications.

The discussed article:

Almeida DRP, Ruzicki J, Xu K, Chin EK. Vision Recovery Velocity, Momentum and Acceleration: Advanced Vitreoretinal Analytics as Measure of Treatment Efficacy for Neovascular Age-Related Macular Degeneration. Clin Ophthalmol. 2021 Jan 18;15:189-194. doi: 10.2147/OPTH.S288621. PMID: 33500611; PMCID: PMC7822233.

Dr. Sabri discusses his group's analysis of various screening criteria to detect visually significant Retinopathy of Prematurity while minimizing unnecessary retinal exams.

Discussed article:

Sabri K, Shivananda S, Farrokhyar F, Selvitella A, Easterbrook B Kin B, Seidlitz W, Lee SK; Canadian Neonatal Network and the Canadian Association of Pediatric Ophthalmology and Strabismus. Refining evidence-based retinopathy of prematurity screening guidelines: The SCREENROP study. Paediatr Child Health. 2019 Aug 12;25(7):455-466. doi: 10.1093/pch/pxz085. PMID: 33173557; PMCID: PMC7606175.

Dr. Raj Maturi from the DRCR Retina Network discusses effect of early anti-VEGF injections in moderate-severe NPDR to prevent vision-threatening complications of diabetic retinopathy. This is the 2-year results of a 4-year study.

Discussed article:

Maturi RK, Glassman AR, Josic K, Antoszyk AN, Blodi BA, Jampol LM, Marcus DM, Martin DF, Melia M, Salehi-Had H, Stockdale CR, Punjabi OS, Sun JK; DRCR Retina Network. Effect of Intravitreous Anti-Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy: The Protocol W Randomized Clinical Trial. JAMA Ophthalmol. 2021 Mar 30:e210606. doi: 10.1001/jamaophthalmol.2021.0606. Epub ahead of print. PMID: 33784735; PMCID: PMC8010644.

Dr. Daniel Lavinsky describes the results of a small randomized controlled clinical trial investigating functional and anatomical outcomes of using nondamaging retinal laser for the treatment of macular telangiectasia type II.

The discussed article:

Lavinsky D, Silva MOD, Chaves AE, Schneider WFM, Lavinsky F, Palanker D. FUNCTIONAL AND STRUCTURAL EFFECTS OF NONDAMAGING RETINAL LASER THERAPY FOR MACULAR TELANGIECTASIA TYPE 2: A Randomized Sham-Controlled Clinical Trial. Retina. 2021 Mar 1;41(3):487-494. doi: 10.1097/IAE.0000000000002882. PMID: 33370517.

Dr. Antoszyk from the DRCR Retina Network discusses Protocol AB, which compared anti-VEGF injections vs immediate pars plana vitrectomy for the treatment of vitreous hemorrhage due to proliferative diabetic retinopathy.

The discussed article:

Antoszyk AN, Glassman AR, Beaulieu WT, Jampol LM, Jhaveri CD, Punjabi OS, Salehi-Had H, Wells JA 3rd, Maguire MG, Stockdale CR, Martin DF, Sun JK; DRCR Retina Network. Effect of Intravitreous Aflibercept vs Vitrectomy With Panretinal Photocoagulation on Visual Acuity in Patients With Vitreous Hemorrhage From Proliferative Diabetic Retinopathy: A Randomized Clinical Trial. JAMA. 2020 Dec 15;324(23):2383-2395. doi: 10.1001/jama.2020.23027. PMID: 33320223; PMCID: PMC7739132.

Dr. Nina Ahuja (@docsleadership) discusses her newly published booked titled "Stress in Medicine, Lessons Learned Through my Years as a Surgeon, from Med School to Residency, and Beyond". In an intimate account of her journey through her medical career, Dr. Ahuja discusses some of hardships and difficulties that she has gone through with the goal of bringing more transparency to the medical education and breaking the culture of silence.

The book is available through Amazon and Apple Books.

Dr. Sridhar (host of the Straight from the Cutter's Mouth podcast) discusses his recent article on the trends of women's representation in VR meetings in the US between 2015 and 2019.

The discusses article:

Sridhar J, Kuriyan AE, Yonekawa Y, Berrocal A, Khan MA, Chan RVP, Haller JA. Representation of Women in Vitreoretinal Meeting Faculty Roles from 2015 through 2019. Am J Ophthalmol. 2021 Jan;221:131-136. doi: 10.1016/j.ajo.2020.09.001. Epub 2020 Sep 9. PMID: 32918901; PMCID: PMC7736466.