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Did you know that The Snooze Button podcast is really just the research phase of a book, made public?
Now, we're "leaking" the first three chapters of the manuscript, in audiobook form, read by the author - Neil Hedley.
Additionally, Dr. Michael Grandner returns with another weekly update on the latest in sleep science.
LINKAPALOOZA:
Here's the link to the page to support The Snooze Button book project.
Here's the first of the two studies Michael mentioned.
Here's the second of the two studies Michael referred to.
Michael Grandner, PhD, is a clinical psychologist and behavioral sleep medicine specialist at the University of Arizona. In this recurring segment, he joins Neil to put new sleep research into context rather than simply repeating the headline.
MENTIONEDDissociable effects of self-reported daily sleep duration on high-level cognitive abilities
The 2018 Wild, Owen and colleagues study of more than 10,000 people discussed in Chapter Three.
Read the Adrian Owen cognition study
Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease
The 2019 Washington University study linking reduced slow-wave sleep with Alzheimer’s-related tau pathology.
Read the tau and slow-wave-sleep study
Wearable technologies for developing sleep and circadian biomarkers
The 2020 international workshop paper Michael references while discussing validation and the role of PSG as a reference standard.
Read the wearable-technology paper
World Sleep Society recommendations for wearable consumer health trackers
The 2025 guidance showing how the field’s view of consumer trackers has evolved while retaining important limits on interpretation.
Read the 2025 recommendations
Brain functional connectivity upon awakening from sleep predicts interindividual differences in dream recall frequency
The French EEG-fMRI dream-recall study Michael discusses.
Read the dream-recall study
Narcolepsy and COVID-19: sleeping on an opportunity?
The 2020 piece by Fabian-Xosé Fernandez, Julie Flygare and Michael Grandner asking what the pandemic might teach researchers about immune triggers and narcolepsy.
Read the Grandner/Fernandez/Flygare paper
Narcolepsy risk and COVID-19
Emmanuel Mignot and Steve Black’s response expanding on the H1N1, vaccination and narcolepsy questions.
Read the Mignot and Black response
Infection, vaccination and narcolepsy type 1: Evidence and potential molecular mechanisms
A 2024 review of the evidence for autoimmune narcolepsy and the specific roles proposed for infection and Pandemrix vaccination.
Read the 2024 narcolepsy review
The neurobiology of SARS-CoV-2 infection
A 2024 Nature Reviews Neuroscience review explaining why COVID’s neurological effects do not automatically prove widespread direct viral invasion of the brain.
Read the SARS-CoV-2 neurobiology review
Known around the world for his WIRED video talking about sleep, Dr. Aric Prather joins the show to talk about his study linking sleep to resistance to the common cold - and how that study can inform our approach to viruses today.
But that's just the beginning in a wide-ranging discussion that touches on everything from vaccinations to tweaking the sleep patterns of a 4-year-old.
Plus, Dr. Michael Grandner is back to discuss the latest in sleep science.
LINKAPALOOZA:
Aric's study about sleep and the common cold
Aric's WIRED video
Recommendations and resources from Michael's group
Aric A. Prather, PhD, is a psychologist and sleep scientist at the University of California, San Francisco. His research examines how sleep and psychological stress affect health, including immune function, cardiovascular risk and health disparities. He also treats insomnia using cognitive behavioral therapy for insomnia.
In August 2026, UCSF named Prather director of its Center for Health and Community. He also directs the UCSF Behavioral Sleep Medicine Research Program and is the author of the 2022 book The Sleep Prescription.
About Dr. Michael GrandnerMichael Grandner, PhD, is a clinical psychologist and behavioral sleep medicine specialist at the University of Arizona. In this recurring segment, he joins Neil to put new sleep research into context rather than simply repeating the headline.
MENTIONEDDr. Aric Prather — UCSF
Current UCSF profile for Prather and his work in behavioral sleep medicine, stress and health.
Aric Prather at UCSF
Prather appointed director of the UCSF Center for Health and Community
UCSF’s August 20, 2026 announcement of Prather’s new leadership role.
UCSF announcement
Behaviorally Assessed Sleep and Susceptibility to the Common Cold
The 2015 rhinovirus challenge study at the center of the interview.
Read the common-cold study
Sleep and Antibody Response to Hepatitis B Vaccination
Prather and colleagues’ study linking objectively measured sleep duration with antibody response and clinical protection following hepatitis B vaccination.
Read the hepatitis B vaccine study
Temporal Links Between Self-Reported Sleep and Antibody Responses to the Influenza Vaccine
The influenza-vaccine study discussed in the episode.
Read the influenza vaccine study
2023 meta-analysis: insufficient sleep and antibody response to vaccination
A later meta-analysis finding a robust reduction in antibody response when short sleep was measured objectively.
Read the 2023 meta-analysis
WIRED: Sleep Expert Explains One Concept in Five Levels of Difficulty
The video Neil and Aric discuss during the interview.
Watch the WIRED video
The Sleep Prescription — Aric A. Prather
Prather’s 2022 practical guide to improving sleep without turning it into another source of pressure.
The Sleep Prescription
Society of Behavioral Sleep Medicine COVID-19 Task Force recommendations
The 2020 pandemic sleep guidance Michael discusses in his weekly segment.
Read the SBSM recommendations
COVID-19-related mobility reduction: heterogeneous effects on sleep and physical activity rhythms
The Singapore wearable study that was emerging when the episode was recorded and was later published using data from 1,824 adults.
Read the Singapore study
Using Sinusoidally-Modulated Noise as a Surrogate for Slow-Wave Sleep
The 2020 computer-science paper behind Michael’s discussion of a neural network that benefited from a sleep-like state.
Read the neural-network paper
William C. Dement, 1928–2020
Stanford Medicine’s remembrance of one of the founders of modern sleep medicine.
Remembering William Dement
Reversing a model of Parkinson’s disease with in situ converted nigral neurons
The dramatic 2020 mouse study Neil brings to Michael at the end of the episode.
Read the original Nature paper
Later PTBP1 replication challenge
A 2022 lineage-tracing study that failed to reproduce the reported astrocyte-to-dopamine-neuron conversion.
Read the 2022 challenge
Ptbp1 deletion does not induce astrocyte-to-neuron conversion
A 2023 Nature Matters Arising paper arguing that viral reporter leakage could account for the apparent conversion reported in the original work.
Read the 2023 critique
Dr, Dayna Johnson's review of how sleep is impacted by race is almost a year old; but it has never had more relevance than it does right now.
Toward the end of the chat, you'll hear the one piece of data from the review that actually made Neil angry.
Plus, we're joined by Dr. Michael Grandner in this first of his weekly visits to update us on the latest in sleep science.
Some Key Takeaways:“So when you encounter experience discrimination or experience, an act of racism, you have a physiologic response, a stress response. And so then that can affect your sleep. When we sleep, there are many things that happen that are important for our health. So whether it’s hormone secretion, whether it’s rest for our blood vessels, whether it’s our memory consolidation, when we have a disturbance to that it causes our sleep to be disturbed, and then we have a poor health outcome.”
“So if it’s memory, we’re thinking about cognitive decline, for example, or if it’s some damage to our cardiovascular system, we’re thinking about a higher risk of harm – hypertension or cardiovascular disease. And so if we have some groups of or some populations such as African-Americans that are consistently encountering discrimination and racism, other stressors, they’re they’re regularly at this and experiencing the stress at this high level, and then consistently have disruptions to sleep, which interrupt these other factors. And so it’s a linear effect. One thing happens and then another, and then you know, it affects your health overall.”
“Black people tend to under-report insomnia. So they under-report problems with sleeping. Some of the reasons for sleep disparities – which date back to slavery times – were that pictures of black people sleeping were labeled as lazy. And so this stereotype has emerged, that if you sleep enough – but really the amount that you need in order to be healthy and operate and have a good quality of life – implies that you are being lazy.”
LINKAPALOOZA
Dr. Dayna Johnson's bio on the Emory University website
Here's the link to the review referenced in the episode linking sleep quality with race.
Click here for the Project Implicit test from Harvard that will privately and anonymously evaluate your unconscious biases.
Dayna Johnson, PhD, MPH, MS, MSW, is an associate professor at Emory University’s Rollins School of Public Health, with appointments in Epidemiology and the Gangarosa Department of Environmental Health.
Her research focuses on sleep epidemiology and health equity — particularly the social and environmental conditions that contribute to insufficient sleep, sleep disorders and downstream health outcomes such as hypertension and cognitive decline. Her work has placed particular emphasis on African American communities and on identifying modifiable environmental targets for reducing sleep disparities.
About Dr. Michael GrandnerMichael Grandner, PhD, is a clinical psychologist and behavioral sleep medicine specialist at the University of Arizona. This episode marks the beginning of his recurring weekly appearances on The Snooze Button to help Neil unpack new sleep research.
MENTIONEDDr. Dayna Johnson — Emory University
Current faculty profile and overview of Johnson’s work on sleep epidemiology, environmental health and health disparities.
Dayna Johnson at Rollins School of Public Health
Are Sleep Patterns Influenced by Race/Ethnicity — a Marker of Relative Advantage or Disadvantage? Evidence to Date
The 2019 review by Dayna Johnson, Chandra Jackson, Natasha Williams and Carmela Alcántara that anchors the main interview.
Read the review
Chicago Area Sleep Study
The population-based actigraphy study behind the 399.5-minute Black and 447.4-minute White average sleep-duration figures discussed in the episode.
Disparities in Sleep Characteristics by Race/Ethnicity
Association Between Sleep Apnea and Blood Pressure Control Among Blacks
Dayna Johnson and colleagues’ Jackson Heart Sleep Study paper on obstructive sleep apnea, blood-pressure control and the very high proportion of previously undiagnosed OSA in the study sample.
Jackson Heart Sleep Study paper
Sleep Disparities in the Era of the COVID-19 Pandemic
The 2020 commentary by Chandra Jackson and Dayna Johnson connecting sleep disparities, the pandemic and the social determinants of health.
Read the commentary
Social and Environmental Determinants of Sleep Health Disparities
Johnson’s 2024 overview of the evidence connecting racism, discrimination, socioeconomic conditions, neighborhood environments and access to care with sleep inequities.
Read the 2024 overview
Day-by-Day Changes in the Indoor Environment and Sleep Health Among African American Adults
A small 2026 study from Johnson’s group examining indoor noise, temperature, carbon dioxide, humidity, pressure and objectively measured sleep.
Read the 2026 study
Project Implicit
The Implicit Association Test discussed by Neil. Best treated as a tool for education, reflection and research rather than as an individual diagnostic test of prejudice.
Project Implicit
Wild Nights: How Taming Sleep Created Our Restless World — Benjamin Reiss
The 2017 cultural history of sleep Dayna references while discussing historical ideas about work, rest and laziness.
Wild Nights on Google Books
Getting Things Done — David Allen
Neil connects Dayna’s habit of writing down bedtime worries with David Allen’s idea of getting commitments out of your head and into a trusted system.
Getting Things Done
Cannabinoid Therapies in the Management of Sleep Disorders
The 2020 systematic review Michael and Neil discuss at the end of the episode: 14 preclinical and 12 clinical studies, with insufficient evidence at the time for routine cannabinoid treatment of sleep disorders.
Sleep Medicine Reviews: Cannabinoid Therapies and Sleep
2025 Cannabinoid Sleep Meta-Analysis
A later randomized-trial meta-analysis finding improvement in subjective sleep quality, particularly with non-CBD formulations, while also reporting high heterogeneity and no clear CBD-only benefit.
Effectiveness of Cannabinoids on Subjective Sleep Quality
Dr. Seema Khosla is the medical director of the North Dakota Center for Sleep, board certified in internal medicine, pulmonary disease, critical care medicine, and sleep medicine. And yes, she’s the Consumer and Clinical Technology Committee with the American Academy of Sleep Medicine.
But she’s ALSO the host of Talking Sleep, a brand new podcast from that same American Academy of Sleep Medicine. As soon as we heard her show, we knew we needed to have Seema on The Snooze Button.
Plenty of sleep information to geek out on here.
LINKAPALOOZA
Talking Sleep - the new podcast from the American Academy of Sleep Medicine
Seema Khosla, MD, is a sleep physician in Fargo, North Dakota, and medical director of the North Dakota Center for Sleep. She is board certified in internal medicine, pulmonary disease, critical care medicine and sleep medicine.
Dr. Khosla has held several leadership roles with the American Academy of Sleep Medicine. She previously chaired its Consumer and Clinical Technology Committee, contributed to the AASM position statement on consumer sleep technology and served on its sleep-telemedicine task force. She currently chairs the AASM Public Awareness Advisory Committee.
She is also the longtime host of Talking Sleep, the AASM podcast devoted to developments in clinical sleep medicine. In 2022, the AASM honored her with its Excellence in Education Award.
MENTIONEDTalking Sleep — American Academy of Sleep Medicine
The AASM podcast Seema had just launched when this conversation was recorded. It remains active in 2026 with Seema as host.
Talking Sleep
Consumer Sleep Technology — AASM Position Statement
The 2018 position statement led by Seema on how clinicians should think about consumer sleep apps, wearables and patient-generated sleep data.
Consumer Sleep Technology: AASM Position Statement
Wearable Sleep Tech: Clinical Use and Best Practices
A 2026 Talking Sleep episode revisiting the exact technology questions Seema and Neil were discussing here in 2020.
Talking Sleep: Wearable Sleep Tech
The Effect of Dogs on Human Sleep in the Home Sleep Environment
The 2017 Mayo Clinic Proceedings study discussed in the episode. A dog in the bedroom was compatible with good sleep efficiency, while having the dog on the bed was associated with lower sleep efficiency.
PubMed: Dogs and Human Sleep
Adult Women’s Sleep, Pet Ownership and Bed-Sharing
The 2018 survey behind headlines about women preferring dogs as bed partners. The results were primarily about perceived disruption, comfort and security and did not establish that dogs objectively produce better sleep than human partners.
Anthrozoös: Women, Pets and Bed-Sharing
Normal Polysomnography Parameters in Healthy Adults
The interactive reference tool developed from the systematic review by Mark Boulos and colleagues, discussed when Neil and Seema compare sleep-lab results with normative data.
PSG Norms
AASM Insomnia Toolkit
Current clinical resources and guidelines for insomnia, including the 2021 guideline strongly recommending CBT-I and advising against sleep hygiene as a stand-alone treatment for chronic insomnia.
AASM Insomnia Toolkit
Julie Flygare is - if you'll pardon the expression - a tireless advocate for people suffering with narcolepsy.
Learn how much you didn't know - including how the movies have made it worse for everyone - and what can be done to help.
LINKAPALOOZA:
Project Sleep's website
Everything else you wanted to know about Julie, you can learn here.
Julie Flygare, JD, is President & CEO of Project Sleep, an internationally recognized patient advocate, speaker and the award-winning author of Wide Awake and Dreaming: A Memoir of Narcolepsy.
Julie began experiencing symptoms of narcolepsy with cataplexy while she was a law student and received her diagnosis in 2007. She earned her B.A. from Brown University and her J.D. from Boston College Law School, and went on to become one of the most visible patient-perspective leaders in sleep medicine.
Through Project Sleep, she has helped build awareness, advocacy, education, scholarships and patient-storytelling programs around narcolepsy and other sleep disorders. She received the Sleep Research Society’s 2024 Public Service Award, and in 2026 her memoir was selected for the Stanford Anesthesia Summer Institute Book Club.
MENTIONEDProject Sleep
Julie’s nonprofit organization focused on sleep-health awareness, sleep disorders, advocacy, education and patient support.
Project Sleep
Julie Flygare
Julie’s website, speaking work, writing and narcolepsy resources.
JulieFlygare.com
Wide Awake and Dreaming: A Memoir of Narcolepsy
Julie’s first-person account of developing narcolepsy in law school, reaching a diagnosis and rebuilding her life around the condition.
Wide Awake and Dreaming
Project Sleep Narcolepsy Resources
Toolkits, fact sheets and guides for people living with narcolepsy, families, educators, healthcare professionals and journalists.
Project Sleep Sleep Resources
Narcolepsy — National Heart, Lung, and Blood Institute
Current NIH overview of narcolepsy symptoms, types, biology, diagnosis and treatment.
NHLBI: Narcolepsy
AASM Treatment Guideline for Central Disorders of Hypersomnolence
American Academy of Sleep Medicine treatment recommendations covering narcolepsy and other central disorders of hypersomnolence.
AASM Guidelines at a Glance
FDA: Oveporexton / Orzeyful Approval
On August 5, 2026, the FDA approved the first medicine for adults with narcolepsy type 1 designed to directly restore orexin signaling.
FDA Approval Announcement
From the publisher's feed
In North America alone, there are about 100 million people with sleep issues. Maybe you’re one of them. Every week, veteran broadcaster Neil Hedley sits down with celebrities, high achievers and…