This coming Friday , the 21st of March 2025 , marks World Down Syndrome Day. According to Down Syndrome South Africa (DSSA), Down syndrome is one of the most common occurring genetic conditions. It is caused by a full or partial extra copy of chromosome 21, known as trisomy 21 which alters the course of development both physically and cognitively. This year DSSA will mark the day with walks in Pretoria, Cape Town, East London, Kimberley, and Polokwane. DSSA is calling on South Africa to improve its support systems. For more we are now joined on the line by Annelise Boot, Office Administrator of Down Syndrome South Africa