This EndoLife

Okay, so we are travelling tomorrow and so I thought I’d just be doing a replay today because of time, but something happened with a client yesterday that I was so excited about, I really wanted to share. Now, I am going to be doing more about this in the future, so this isn’t going to be a deep dive episode as I just don’t have the time for that today, but I really wanted to get this info out there because I know so many of you are struggling right now with MCAS, POTS, ADHD and hEDS, that I just felt like I had to get something out there.

Show Notes:

Mira link

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Today we’re continuing with our Study Spotlight series on the study entitled ‘Dietary Modification and Supplement Use For Endometriosis Pain’. If you’re new to the series and want to understand what this study was about, the strengths and weaknesses and my overall thoughts on the study, go to episode 365, and the link to that is in the show notes.

Today, we’re diving into one of the supplements with the best response rate, and that is serrapeptase.

Show Notes:

Main study

https://www.theendobellycoach.com/podcast/new-endo-survey-study-review

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831953

Serrepeptase overall research

https://pubmed.ncbi.nlm.nih.gov/29618875/

https://pubmed.ncbi.nlm.nih.gov/23380245/

https://pmc.ncbi.nlm.nih.gov/articles/PMC7585045/

https://pmc.ncbi.nlm.nih.gov/articles/PMC8265778/

https://pmc.ncbi.nlm.nih.gov/articles/PMC8624573/#B8-medicines-08-00068

https://www.mdpi.com/2218-273X/12/10/1468

Serrepeptase inflammation research

https://www.sciencedirect.com/science/article/pii/S181808761630160X

https://www.mdpi.com/2218-273X/12/10/1468

PgE2

https://www.sciencedirect.com/science/article/abs/pii/0090698085902084?via=ihub

https://pubmed.ncbi.nlm.nih.gov/20511671/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4512562/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3081099/

Interleukin 6

https://pubmed.ncbi.nlm.nih.gov/38428575/

https://www.ijfs.ir/article_700967_82be9d71bf5a0f57430b545d9df3ec27.pdf

https://pmc.ncbi.nlm.nih.gov/articles/PMC5556658

https://pmc.ncbi.nlm.nih.gov/articles/PMC9265783

https://pmc.ncbi.nlm.nih.gov/articles/PMC7943546

https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0607-6

Endo and serrepeptase/proteolytic enzyme research

https://journals.sagepub.com/doi/abs/10.5301/je.5000215

https://www.sciencedirect.com/science/article/abs/pii/S0378432019305895

VEGF and endo

https://pmc.ncbi.nlm.nih.gov/articles/PMC3850339/

https://pubmed.ncbi.nlm.nih.gov/9688413/

https://www.frontiersin.org/journals/global-womens-health/articles/10.3389/fgwh.2022.856316/full

https://pubmed.ncbi.nlm.nih.gov/8671190/

TGF-α and endo

https://www.sciencedirect.com/science/article/abs/pii/000293789390356N

https://pubmed.ncbi.nlm.nih.gov/1923211/

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1447-0578.2005.00098.x

https://www.sciencedirect.com/science/article/pii/S2666335X22000386

Dosing

https://www.sciencedirect.com/science/article/pii/S1743919113000265

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831953

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Today we’re starting a new series and that’s looking into a major new endometriosis study, and doing a deep dive into the dietary changes and supplements it analysed and individually investigating each of them, so that we have a broader understanding of each of these tools.

I won’t necessarily be doing one episode on the series every week, as there are many components of the study we’ll be looking at, so I don’t want to bore you guys with the same topic over and over, but expect us to dip in and out of this series over the next few months.

Now, the study in question is: Dietary Modification and Supplement Use For Endometriosis Pain

The study was a survey study, with 2858 participants, out of which 2388 had endometriosis. It is the largest international survey study we have to date, which is one of the reasons why it’s such a big deal.

Show Notes:

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831953

6-12 month 1:1 coaching programme

Single sessions and mini coaching packages

Need more help or want to learn how to work with me?

Free resources:

This podcast! 

⁠Endometriosis Net Column⁠

⁠Endometriosis News Column⁠

⁠Substack ⁠

⁠Instagram⁠

Ways to work with me:

⁠This EndoLife, It Starts with Breakfast digital cookbook⁠

⁠Masterclasses in endo nutrition, surgery prep and recovery and pain relief⁠

⁠Live and Thrive with Endo: The Foundations DIY course⁠

⁠One to one coaching info and application⁠

Produced by ⁠Chris Robson

In this week’s episode we are continuing on the ADHD and endometriosis theme, and I have another guest for you - this time, one you may recognise from the show previously; Natalia Kasnakidis.

Natalia is an award-winning Career & Performance Coach, Speaker and women’s health advocate – recently recognised by Management Today as one the UK’s 35 Women Under 35.

After being diagnosed with hEDS at 21, she rebuilt her health and confidence whilst growing multi-million-pound brands and high-performing teams at top global ad agencies. 

Now, as founder of The Limitless Collective, she helps women achieve their career ambitions in a way that's sustainable, fulfilling & supports their wellbeing. She specialises in supporting women who are neurodivergent or managing chronic health conditions – bringing a holistic, mind-body approach to professional growth.

Today we are talking about her story of how she navigated chronic illness early on in her career, and how it forced her to make essential changes that were outside of typical societal norms, but allowed her to progress and develop her career, even with ADHD, hypermobile-EDS and suspected endometriosis. We then discuss how this experience led her to found The Limitless Collective to help other women do the same, and her tips and strategies for listeners who want to thrive in their careers and businesses, whilst also caring for their health and managing their conditions and neurodivergence.

Show Notes:

Connect with Natalia:

https://thelimitlesscollective.co

@thelimitlesscollective.co

Research:

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.786916/full

https://www.sciencedirect.com/science/article/pii/S0022395621004258

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This podcast! 

⁠Endometriosis Net Column⁠

⁠Endometriosis News Column⁠

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⁠Instagram⁠

Ways to work with me:

⁠This EndoLife, It Starts with Breakfast digital cookbook⁠

⁠Masterclasses in endo nutrition, surgery prep and recovery and pain relief⁠

⁠Live and Thrive with Endo: The Foundations DIY course⁠

⁠One to one coaching info and application⁠

Produced by ⁠Chris Robson

Following on from last week’s episode about ADHD and menopause, I am resharing my interview with Adele Wimsett, who is talking to us about ADHD and the connection with endometriosis.

In this episode we discuss:

• What ADHD is

• Why it presents differently in females and cyclical people and what this means for diagnosis

• How hormones affect ADHD traits

• What impact hormones have on traits during different hormonal phases of a cyclical person’s life

• How we can support our hormones to live an adhd friendly lifestyle.

Show Notes:

Adele’s website

Adele’s Instagram

Research:

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.786916/full

https://www.sciencedirect.com/science/article/pii/S0022395621004258

Need more help or want to learn how to work with me?

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This podcast! 

⁠Endometriosis Net Column⁠

⁠Endometriosis News Column⁠

⁠Substack ⁠

⁠Instagram⁠

Ways to work with me:

⁠This EndoLife, It Starts with Breakfast digital cookbook⁠

⁠Masterclasses in endo nutrition, surgery prep and recovery and pain relief⁠

⁠Live and Thrive with Endo: The Foundations DIY course⁠

⁠One to one coaching info and application⁠

Produced by ⁠Chris Robson

Dr Helen Wall is an NHS doctor, who runs a menopause clinic and is passionate about spreading awareness of ADHD in women, especially in perimenopause. She is a resident doctor on the BBC and a columnist for Woman Magazine.

With those of us with endo more likely to have ADHD, and symptoms worsening during perimenopause, I invited Dr Helen onto the show, to help us understand what ADHD is, how to look for the signs and symptoms, what we can expect of this condition during perimenopause and how to seek support and treatment.

For those of you who aren’t aware, ADHD presents differently in women, and is often missed for decades, if not for a woman’s entire lifetime. I have seen first hand how undiagnosed ADHD can hugely impact quality of life, and how it worsens in my clients during perimenopause. As a result of what I’ve personally experienced and witnessed, I think that this is one of the most important interviews I’ve ever had on the show.

Dr Helen is a wealth of knowledge and I highly recommend you follow her work on Instagram (I’ve put the link in the show notes), but for now, dive in!

Show notes

https://tvhealthdoctor.com

https://www.instagram.com/doctorhelenwall/ @doctorhelenwall

https://www.sciencedirect.com/science/article/abs/pii/S0002937820302210

Need more help or want to learn how to work with me?

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This podcast! 

Endometriosis Net Column

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Ways to work with me:

This EndoLife, It Starts with Breakfast digital cookbook

Masterclasses in endo nutrition, surgery prep and recovery and pain relief

Live and Thrive with Endo: The Foundations DIY course

One to one coaching info and application

Produced by Chris Robson

Seed cycling. You might have heard of it, you might have tried it, you might have had your doctor dismiss it or you may think it’s just another wellness trend.

But admittedly, whilst it’s trendy, it’s not just hype.

Show notes

Flax studies

https://academic.oup.com/jcem/article-abstract/77/5/1215/2649961?redirectedFrom=fulltext&login=false

https://pubmed.ncbi.nlm.nih.gov/14749240/

Zinc

https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-024-01442-z

https://pubmed.ncbi.nlm.nih.gov/36920672/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3275394/

https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional

Vit E

https://ovarianresearch.biomedcentral.com/articles/10.1186/1757-2215-2-1

https://www.nature.com/articles/s41598-022-09082-3

https://link.springer.com/article/10.1186/1477-7827-7-54

https://rbej.biomedcentral.com/articles/10.1186/s12958-023-01126-1

https://www.clinicalnutritionespen.com/article/S2405-4577(22)00500-9/abstract

Magnesium

https://www.ijwhr.net/pdf/pdf_IJWHR_624.pdf

https://pmc.ncbi.nlm.nih.gov/articles/PMC8972862/#ref18

https://pmc.ncbi.nlm.nih.gov/articles/PMC11013220/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3198864/

https://pubmed.ncbi.nlm.nih.gov/6747732/

https://pubmed.ncbi.nlm.nih.gov/2675496/

Seed Cycling Clinical Study by BeeYa Wellness

https://cdn.shopify.com/s/files/1/0514/1102/6118/files/Beeya_Clinical_Study_-_Detailed_Report.pdf?v=1741313849

Calcium

https://www.tandfonline.com/doi/abs/10.1080/07315724.2000.10718920

https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1079417/full#B44

https://www.sciencedirect.com/science/article/pii/S1028455909602710?via=ihub

https://www.ajog.org/article/S0002-9378(34)90970-4/abstract

PCOS study

https://pmc.ncbi.nlm.nih.gov/articles/PMC10261760/

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Masterclasses in endo nutrition, surgery prep and recovery and pain relief

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One to one coaching info and application

Produced by Chris Robson

Okay so last week I said I had finished with the low FODMAP series, but I changed my mind! I wanted to do one more on the topic, and that’s for my endo peeps who also have postural tachycardia syndrome or dysautonomia, and/or Ehlers Danlos Syndrome.

Show notes

Low FODMAP diet info

https://www.monashfodmap.com/about-fodmap-and-ibs/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4918736/

EDS definition

https://www.ehlers-danlos.com/what-is-eds/

POTS definition

https://www.standinguptopots.org/POTSsubtypes

Long covid

https://nurosym.org/blogs/in-conversation-with/dr-david-strain

https://news.utoledo.edu/index.php/03_24_2025/covid-19-brought-about-a-large-rise-in-pots-cases#:~:text=The UToledo study, however, points,COVID may actually have POTS.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10166245/

https://pmc.ncbi.nlm.nih.gov/articles/PMC12079877/#:~:text=The pooled prevalence of long,the forest plot in Fig.

EDS and endometriosis

https://www.ehlers-danlos.com/wp-content/uploads/2022/12/N-Blagowidow-2018Baltimore-OB-GYN-and-EDS-HSD-S.pdf

https://pubmed.ncbi.nlm.nih.gov/9420859/

https://www.eds.clinic/articles/endometriosis-ehlers-danlos-syndrome

https://www.theendobellycoach.com/podcast/endometriosis-and-ehlers-danlos-syndrome?rq=Ehlers

IBS and POTS

https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1342351/full3

https://www.researchgate.net/publication/284068911_Gastrointestinal_Dysfunction_in_Postural_Tachycardia_Syndrome#:~:text=of these patients.-,...,[37]. …

https://www.researchgate.net/publication/345601295_Postural_Tachycardia_Syndrome_and_the_Gut

Low FODMAP diet and POTS

https://www.potsuk.org/managingpots/diet-and-fluids-2/

https://sci-hub.se/10.1016/j.autneu.2018.09.003

https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2019/06/POTS-June-2019.pdf

Low FODMAP and EDS

https://www.researchgate.net/publication/353970119_Literature_Review_Does_following_a_low_FODMAP_diet_improve_functional_gastrointestinal_symptoms_in_Ehlers-Danlos_Syndrome_Hypermobility_type_through_supporting_the_role_of_nutritional_intervention

https://www.ehlers-danlos.com/2017-eds-classification-non-experts/gastrointestinal-involvement-ehlers-danlos-syndromes/

https://practicalgastro.com/2024/06/17/nutritional-considerations-for-hypermobile-ehlers-danlos-syndrome/#:~:text=If symptoms do not improve,compared to IBS-C controls.

IBS and EDS

https://www.eds.clinic/articles/gastrointestinal-issues-ehlers-danlos-syndrome-guide

https://pmc.ncbi.nlm.nih.gov/articles/PMC7255528/

https://pubmed.ncbi.nlm.nih.gov/29687534/

SIBO and EDS

https://pubmed.ncbi.nlm.nih.gov/37858959/

SIBO and POTS

https://pubmed.ncbi.nlm.nih.gov/29326369/

https://sci-hub.se/10.1016/j.autneu.2018.09.003

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Produced by Chris Robson

Recently we’ve been talking about the low FODMAP diet and how it can be helpful for histamine issues and endometriosis symptoms… but what about what it was designed for - IBS, and by default, SIBO?

Show notes

Low FODMAP diet info

https://www.monashfodmap.com/about-fodmap-and-ibs/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4918736/

IBS and SIBO

https://www.youtube.com/watch?v=Sv8LjTgpmP0

https://www.ibssmart.com/sibo-symptoms-and-diagnosis

https://www.nature.com/articles/s41598-022-05933-1

https://www.msjonline.org/index.php/ijrms/article/view/15048

SIBO and endometriosis

https://pubmed.ncbi.nlm.nih.gov/39959963/

https://pubmed.ncbi.nlm.nih.gov/9660426/

IBS and endometriosis

https://pmc.ncbi.nlm.nih.gov/articles/PMC9357916/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11668458/

https://pubmed.ncbi.nlm.nih.gov/18715239/

https://pubmed.ncbi.nlm.nih.gov/28303579/

https://pubmed.ncbi.nlm.nih.gov/18715239/

Microbiome and endo

https://pmc.ncbi.nlm.nih.gov/articles/PMC10747908/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10904627/

https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1552134/full

https://www.mdpi.com/1422-0067/26/11/5144

https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1110824/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC9962481/

Endo and low FODMAP diet

https://pubmed.ncbi.nlm.nih.gov/28303579/

https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-025-03715-1

https://pmc.ncbi.nlm.nih.gov/articles/PMC12107219/

SIBO treatment options

https://endometriosisnews.com/2020/12/17/elemental-diet-sibo-treatment/

https://endometriosisnews.com/2020/11/05/antimicrobial-herbs-treat-sibo-right-for-me/

https://endometriosisnews.com/2020/10/08/antibiotics-treat-sibo-guide/

https://endometriosisnews.com/2020/09/24/sibo-treatment-what-to-know/

https://www.theendobellycoach.com/this-endolife-podcast-episodes/how-to-treat-sibo-with-dr-allison-siebecker

Need more help or want to learn how to work with me?

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This EndoLife, It Starts with Breakfast digital cookbook

Masterclasses in endo nutrition, surgery prep and recovery and pain relief

Live and Thrive with Endo: The Foundations DIY course

One to one coaching info and application

Produced by Chris Robson

Last week I talked about the low FODMAP diet for lowering histamine levels and helping to improve MCAS or histamine intolerance symptoms, but today I want to talk about the low FODMAP diet specifically for endometriosis and what the research shows so far.

Show notes

Low FODMAP diet info

https://www.monashfodmap.com/about-fodmap-and-ibs/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4918736/

Studies referenced

https://pubmed.ncbi.nlm.nih.gov/28303579/

https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-025-03715-1

https://pmc.ncbi.nlm.nih.gov/articles/PMC12107219/

Need more help or want to learn how to work with me?

Free resources:

This podcast! 

Endometriosis Net Column

Endometriosis News Column

Newsletter

Instagram

Ways to work with me:

This EndoLife, It Starts with Breakfast digital cookbook

Masterclasses in endo nutrition, surgery prep and recovery and pain relief

Live and Thrive with Endo: The Foundations DIY course

One to one coaching info and application

Produced by Chris Robson