The HazMat Guys

THMG273 – TMAH – A chemical analysis


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From a recent FB post Mike caught onto this chemical and began a conversation about the oddities of it and the tactical considerations.
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Tetramethylammonium hydroxide. Man that's a mouthful. And is not something I had heard about until eguine ngai posted something about it on the hazmat group on facebook. The story that he told got me interested in the chemical. It's found in industrial settings. Specializing in the electronics world and many research applications. While doing more research on it I found it kinda interesting in regards to how lethal this seemed vs what its hazards were listed in the GHS. So i wanted to touch on that as wellTetramethylammonium hydroxide with a cas# of 75-59-2 is often found in two different types of solutions. It is found as water or aqueous solution as well in solutions of methanol. Do you find it odd at all that the cas number for these doesn’t change. I mean methanol and water are so different yet the same cas#?Talk about thatThey are found in concentrations of about 2 to 25%Besides being in solution a salt form of TMAH exists and can be found in crystallized form. So you might see them like you would a saltSo we were curious just exactly what this stuff does. Like what would one use Tetramethylammonium hydroxide for anyway. And let me tell you the answer to that question left me with more questions than answers. It performs action that i have never even heard of on things i have neer even heard ofthis is from wikipedia One of the industrial uses of TMAH is for the anisotropic etching of silicon.[10] What is anisotropic?I am glad you asked because I didn't have a clue either. It basically makes the surface of a substance different depending on its orientation. When i looked this up because i still didn't understand what the hell that meant, it gave an example of wood. A log has different characteristics going with the grain then against the grain. It's easier to chop wood with the grain but hard to break it apart against the grain.It is used as a basic solvent in the development of acidic photoresist in the photolithography process, and is highly effective in stripping photoresist. TMAH has some phase transfer catalyst properties, and is used as a surfactant in the synthesis of ferrofluid, to inhibit nanoparticle aggregation.TMAH is the most common reagent currently used in thermochemolysis, an analytical technique involving both pyrolysis and chemical derivatization of the analyte.[11Let's take a look at some of the chemical and physical properties of this chemical.First off it is a very strong base.When we examine some of the accidents a bit we will see that skin damage and tissue damage was a huge issue.In a solid form it has a melting point of 153 degrees and will decompose before that liquid boils. It has an auto ignition temperature of 878 degree F. So it is clearly toxic long before it will be flammableIt has no available data on the vapor pressure. What are some of the hazards of this?Under the GHS its is acute toxicity oral and dermalSkin corrosive and eye damageWill have specific target organ toxicity in a single exposure to the central nervous system and with repeated exposure will target thymus gland and liverThe NFPA labels this a 3 in the health hazard. Lucky eugene ngai put together a few case study accidents on this chemical. And reading and hearing about them really gives you a pretty deep respect for the chemical. This comes from mEguines company “chemically speaking LLC” and you can find this and all sorts of other info on chemicals on his site.The first one speaks of a more recent event.
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