Tiny Matters

In the mid-20th century, psychedelic research to treat conditions like depression began to take off, yet by 1970 almost all of that work came to a screeching halt. But guess what? It’s back, and access to guided therapy to treat various mental health conditions is becoming a reality. The link to The New York Times article about Roland Griffiths is here. The Tiny Show & Tell stories are here and here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here. 

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There's a whole lot of information (and misinformation) out there about depression, as well as debate surrounding how it's treated. In this episode, Sam and Deboki unpack this complex mood disorder that impacts over 300 million people across the globe as well as the effectiveness of SSRIs and the work being done to find better drugs. A link to David Hellerstein's new book The Couch, The Clinic and the Scanner: Stories from Three Revolutionary Eras of the Mindis here. The Tiny Show & Tell stories are here and here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here.

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The first computer was created in 1945 and came in at double the size of a one-bedroom apartment. Just 50 years later, the architecture of the computer on a chip that measured just 7.44 by 5.29 millimeters in size. And now, computers have gotten smaller and smaller [looks down at Apple Watch]. So how did we go from apartment-sized calculators to the tiny devices we use to look up cat pictures when we’re bored? And just how much smaller can we go? Links to the Tiny Show & Tell stories here and here. Want to drink your coffee (or beverage of choice) in style? Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here. 

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The question of whether or not life exists on other planets is an important and interesting one. But maybe the more intriguing question is, “what if it does?” In this episode of Tiny Matters, Sam and Deboki chat with science writer Jaime Green about what it would mean for life to exist beyond Earth. Her book, “The Possibility of Life: Science, Imagination, and Our Quest for Kinship in the Cosmos,” is a mix of history, astronomy, biology, philosophy, and sci-fi, and just hit store shelves. To order a copy, check out local bookstores and other options here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here. 

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Since the very beginning of the space age, people have been wondering if algae could provide a life support system beyond our planet. From dozens of studies over the last 60 years, we’ve figured out that algae probably can thrive for up to a year in space. But what if we wanted to live permanently on another planet, like Mars? This episode is all about algae: how it shaped early Earth, how we might use it to terraform planets in the future, and how it’s being used in biomanufacturing to hopefully get us away from relying on fossil fuels. Links to the Tiny Show & Tell stories here and here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here.

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For millennia, humans have looked to the sea to find medicine. Today, medical treatments that come from the ocean have been clinically approved for pain, cancer, and Alzheimer’s disease, and over a dozen more are in clinical trials. In this episode of Tiny Matters, Sam and Deboki are tackling marine natural products—things like proteins, fats, and other molecules that aquatic organisms produce—that humans are hoping to use to treat the diseases that plague us. Links to the Tiny Show & Tell stories are here and here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here. 

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If you’ve been watching HBO’s The Last of Us, you might have some questions about fungus zombies and maybe fungi in general. In this bonus episode, Sam calls up field mycologist Giuliana Furci for a little fungi 101 and to talk fungi fact vs. fiction in the show. We promise there will be no jump scares! Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here.

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Around 400 million tons of plastic are produced annually, which is the estimated weight of all of humanity! Plastic-covered beaches and litter on the side of the road is gross and depressing, but it turns out that stuff is just the visible tip of the iceberg. Plastic breaks down into tiny, tiny pieces that have now been found in almost every ecosystem on the planet—from the bottom of the ocean to mountain ranges in Europe. They’ve also been found in us. This episode of Tiny Matters is all about microplastics and both the molecules that stick to them and the ones they release, like forever chemicals (aka PFAS). Find Imari's upcoming book about plastics here. If you're looking for more info on microplastics monitoring and policy, check out  this episode of Stereo Chemistry from our friends at C&EN. If you're in the United States: for data on your region's drinking water go to the Environmental Working Group's website here. The Tiny Show & Tell stories this week can be found here and  here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here. 

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In this episode of Tiny Matters, Sam and Deboki go on a detection dog deep dive. These are dogs who can sniff out basically anything, from explosives to invasive pythons to diseases like cancer and COVID-19. How are they trained? Are certain breeds better at recognizing certain odors? And, come to think of it, how do any of us smell things? Links to the Tiny Show & Tell stories here and here. Pick up a Tiny Matters mug here! All Tiny Matters transcripts are available here.

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Maybe you know Hank Green from Vlogbrothers or CrashCourse. Maybe he taught you something on TikTok. Maybe you’ve read one of his books. Or maybe you know him from about a dozen other things. Hank does a lot, so Sam and Deboki were psyched to get a chance to chat with him. Even more about Hank at https://hankgreen.com/ Episode transcripts at acs.org/tinymatters 

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