Our 11th Annual Update Course in Pediatric Surgery was held past August. In this video series, we'll recap the sessions and share the main highlights with you. Today, we'll talk about "Botox in Hirschsprung Disease". Joining the discussion are Drs. Steven Lee, Caitlin Smith and Julia Grabowski.

Host: Em Gootee, MD

References:

https://pubmed.ncbi.nlm.nih.gov/21238663/

Patrus B, Nasr A, Langer JC, Gerstle JT. Intrasphincteric botulinum toxin decreases the rate of hospitalization for postoperative obstructive symptoms in children with Hirschsprung disease. J Pediatr Surg. 2011 Jan;46(1):184-7. doi: 10.1016/j.jpedsurg.2010.09.089. PMID: 21238663.

https://pubmed.ncbi.nlm.nih.gov/35690464/

Svetanoff WJ, Lim-Beutal IIP, Wood RJ, Levitt MA, Rentea RM. The utilization of botulinum toxin for Hirschsprung disease. Semin Pediatr Surg. 2022 Apr;31(2):151161. doi: 10.1016/j.sempedsurg.2022.151161. Epub 2022 Apr 8. PMID: 35690464.

https://pubmed.ncbi.nlm.nih.gov/33422904/

Rentea RM, Noel-MacDonnell JR, Bucher BT, Dorman MR, Lautz TB, Pruitt LCC, Oyetunji TA. Impact of Botulinum Toxin on Hirschsprung-Associated Enterocolitis After Primary Pull-Through. J Surg Res. 2021 May;261:95-104. doi: 10.1016/j.jss.2020.12.018. Epub 2021 Jan 7. PMID: 33422904.

https://pubmed.ncbi.nlm.nih.gov/37221126/

Encisco EM, Lim IIP, Velazco CS, Rosen NG, Garrison AP, Rymeski B, Frischer JS. Hirschsprung-Associated Enterocolitis at a Referral Institution: A Retrospective Review. J Pediatr Surg. 2023 Aug;58(8):1578-1581. doi: 10.1016/j.jpedsurg.2023.04.008. Epub 2023 Apr 20. PMID: 37221126.

https://pubmed.ncbi.nlm.nih.gov/33001257/

Svetanoff WJ, Dekonenko C, Osuchukwu O, Oyetunji TA, Aguayo P, Fraser JD, Juang D, Snyder CL, Hendrickson R, Peter SS, Rentea RM. Inpatient management of Hirschsprung's associated enterocolitis treatment: the benefits of standardized care. Pediatr Surg Int. 2020 Dec;36(12):1413-1421. doi: 10.1007/s00383-020-04747-4. Epub 2020 Oct 1. PMID: 33001257.