We’re back with 26th episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review articles covering the most interesting and relevant topics in the field.

These articles are either chosen by JPS editors or our collaborators. We present these reviews as short news pieces with a summarization of key points.

Whether you're a trainee, attending, or an advanced medical professional, tune in to our podcast for a dose of medical knowledge in every episode. Stay up to date on the latest trends and advancements in pediatric surgery with "Quick Literature Updates".

Host: Em Gootee

https://pubmed.ncbi.nlm.nih.gov/39826968/

St Peter SD, Noel-MacDonnell JR, Hall NJ, Eaton S, Suominen JS, Wester T, Svensson JF, Almström M, Muenks EP, Beaudin M, Piché N, Brindle M, MacRobie A, Keijzer R, Engstrand Lilja H, Kassa AM, Jancelewicz T, Butter A, Davidson J, Skarsgard E, Te-Lu Y, Nah S, Willan AR, Pierro A. Appendicectomy versus antibiotics for acute uncomplicated appendicitis in children: an open-label, international, multicentre, randomised, non-inferiority trial. Lancet. 2025 Jan 18;405(10474):233-240. doi: 10.1016/S0140-6736(24)02420-6. Erratum in: Lancet. 2025 Feb 8;405(10477):468. doi: 10.1016/S0140-6736(25)00206-5. PMID: 39826968.

https://pubmed.ncbi.nlm.nih.gov/40032536/

Xu TO, Hanke RE, Das K, Bowser M, Hisam B, Samuk I, Wissanji H, Teeple E, Mayhew A, Myseros JS, Badillo A, Levitt MA, Varda BK, Feng C. VACTERL Screening in Newborns With Anorectal Malformations - An Opportunity to Optimize Screening Practices, add Gynecologic and Spinal Conditions, and Utilize a New Acronym: VACTE(G)RLS. J Pediatr Surg. 2025 Jun;60(6):162252. doi: 10.1016/j.jpedsurg.2025.162252. Epub 2025 Feb 20. PMID: 40032536.

https://pubmed.ncbi.nlm.nih.gov/38245889/

Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Biban P, Carrol ED, Chiotos K, Chisti MJ, DeWitt PE, Evans I, Flauzino de Oliveira C, Horvat CM, Inwald D, Ishimine P, Jaramillo-Bustamante JC, Levin M, Lodha R, Martin B, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Rebull MN, Russell S, Scott HF, de Souza DC, Tissieres P, Weiss SL, Wiens MO, Wynn JL, Kissoon N, Zimmerman JJ, Sanchez-Pinto LN, Bennett TD; Society of Critical Care Medicine Pediatric Sepsis Definition Task Force. International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024 Feb 27;331(8):665-674. doi: 10.1001/jama.2024.0179. PMID: 38245889; PMCID: PMC10900966.

We’re back with 25th episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review articles covering the most interesting and relevant topics in the field.

These articles are either chosen by JPS editors or our collaborators. We present these reviews as short news pieces with a summarization of key points.

Whether you're a trainee, attending, or an advanced medical professional, tune in to our podcast for a dose of medical knowledge in every episode. Stay up to date on the latest trends and advancements in pediatric surgery with "Quick Literature Updates".

Host: Em Gootee

https://pubmed.ncbi.nlm.nih.gov/38914511/

Huerta CT, Beres AL, Englum BR, Gonzalez K, Levene T, Wakeman D, Yousef Y, Gulack BC, Chang HL, Christison-Lagay ER, Ham PB 3rd, Mansfield SA, Kulaylat AN, Lucas DJ, Rentea RM, Pennell CP, Sulkowski JP, Russell KW, Ricca RL, Kelley-Quon LI, Tashiro J, Rialon KL; American Pediatric Surgical Association Outcomes and Evidence-Based Practice Committee. Management and Outcomes of Pediatric Lymphatic Malformations: A Systematic Review From the APSA Outcomes and Evidence-Based Practice Committee. J Pediatr Surg. 2024 Oct;59(10):161589. doi: 10.1016/j.jpedsurg.2024.05.019. Epub 2024 Jun 6. PMID: 38914511.

https://pubmed.ncbi.nlm.nih.gov/39743432/

Moturu A, Coleman M, Mets C, Thompson V, Grant C, Ko CY, Saito JM, Berman L, Wakeman D. Identifying Quality Improvement Targets After Pediatric Gastrostomy Tube Insertion: A NSQIP-Pediatric Pilot Study. J Pediatr Surg. 2025 Jun;60(6):162107. doi: 10.1016/j.jpedsurg.2024.162107. Epub 2024 Dec 17. PMID: 39743432.

https://pubmed.ncbi.nlm.nih.gov/38733138/

Kollin C, Nordenskjöld A, Ritzén M. Testicular volume at puberty in boys with congenital cryptorchidism randomised to treatment at different ages. Acta Paediatr. 2024 Aug;113(8):1949-1956. doi: 10.1111/apa.17270. Epub 2024 May 11. PMID: 38733138.

We’re back with 24th episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review articles covering the most interesting and relevant topics in the field.

These articles are either chosen by JPS editors or our collaborators. We present these reviews as short news pieces with a summarization of key points.

Whether you're a trainee, attending, or an advanced medical professional, tune in to our podcast for a dose of medical knowledge in every episode. Stay up to date on the latest trends and advancements in pediatric surgery with "Quick Literature Updates".

Host: Em Gootee

https://pubmed.ncbi.nlm.nih.gov/38914509/

Donati F, Cipriani MS, Pistorio A, Guerriero V, Mattioli G, Torre M. Pectus Bar Dislocation: Comparison Between Three Different Stabilization Techniques Adopted in a Single Centre. J Pediatr Surg. 2024 Oct;59(10):161591. doi: 10.1016/j.jpedsurg.2024.05.021. Epub 2024 Jun 4. PMID: 38914509.

https://pubmed.ncbi.nlm.nih.gov/38834671/

Males I, Boban Z, Kumric M, Vrdoljak J, Berkovic K, Pogorelic Z, Bozic J. Applying an explainable machine learning model might reduce the number of negative appendectomies in pediatric patients with a high probability of acute appendicitis. Sci Rep. 2024 Jun 4;14(1):12772. doi: 10.1038/s41598-024-63513-x. PMID: 38834671; PMCID: PMC11150468.

https://pubmed.ncbi.nlm.nih.gov/37957103/

Rauh J, Dantes G, Wallace M, Collings A, Sanin GD, Cambronero GE, Bosley ME, Ganapathy AS, Patterson JW, Ignacio R, Knod JL, Slater B, Callier K, Livingston MH, Alemayehu H, Dukleska K, Scholz S, Santore MT, Zamora IJ, Neff LP. Transcystic Laparoscopic Common Bile Duct Exploration for Pediatric Patients with Choledocholithiasis: A Multi-Center Study. J Pediatr Surg. 2024 Mar;59(3):389-392. doi: 10.1016/j.jpedsurg.2023.10.046. Epub 2023 Oct 21. PMID: 37957103.

We’re back with 23rd episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review articles covering the most interesting and relevant topics in the field.

These articles are either chosen by JPS editors or our collaborators. We present these reviews as short news pieces with a summarization of key points.

Whether you're a trainee, attending, or an advanced medical professional, tune in to our podcast for a dose of medical knowledge in every episode. Stay up to date on the latest trends and advancements in pediatric surgery with "Quick Literature Updates".

Host: Em Gootee

0:00 Introduction

0:39 Locum Tenens and Pediatric Surgery: A Position Statement and Practice Guidelines From the American Pediatric Surgical Association (APSA)

1:40 Validation of the Clavien-Madadi Classification for Unexpected Events in Pediatric Surgery: A Collaborative ERNICA Project

2:50 Transitional Care in Anorectal Malformation and Hirschsprung's Disease: A Systematic Review of Challenges and Solutions

4:03 Outro

https://pubmed.ncbi.nlm.nih.gov/38806318/

Fahy AS, Klima DA, Gillam MM, Aprahamian CJ, Kim SS, Kokoska ER, Teeple EA, Weiss RG, Escobar MA Jr. Locum Tenens and Pediatric Surgery: A Position Statement and Practice Guidelines From the American Pediatric Surgical Association (APSA). J Pediatr Surg. 2024 Oct;59(10):161567. doi: 10.1016/j.jpedsurg.2024.04.021. Epub 2024 May 8. PMID: 38806318.

https://pubmed.ncbi.nlm.nih.gov/38582705/

Madadi-Sanjani O, Kuebler JF, Brendel J, Costanzo S, Granström AL, Aydin E, Loukogeorgakis S, Lacher M, Wiesner S, Domenghino A, Clavien PA, Mutanen A, Eaton S, Ure BM. Validation of the Clavien-Madadi Classification for Unexpected Events in Pediatric Surgery: A Collaborative ERNICA Project. J Pediatr Surg. 2024 Sep;59(9):1672-1679. doi: 10.1016/j.jpedsurg.2024.03.022. Epub 2024 Mar 16. PMID: 38582705.

https://pubmed.ncbi.nlm.nih.gov/37996349/

Plascevic J, Shah S, Tan YW. Transitional Care in Anorectal Malformation and Hirschsprung's Disease: A Systematic Review of Challenges and Solutions. J Pediatr Surg. 2024 Jun;59(6):1019-1027. doi: 10.1016/j.jpedsurg.2023.10.066. Epub 2023 Nov 2. PMID: 37996349.

We’re back with 22nd episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review articles covering the most interesting and relevant topics in the field.

These articles are either chosen by JPS editors or our collaborators. We present these reviews as short news pieces with a summarization of key points.

Whether you're a trainee, attending, or an advanced medical professional, tune in to our podcast for a dose of medical knowledge in every episode. Stay up to date on the latest trends and advancements in pediatric surgery with "Quick Literature Updates".

Host: Em Gootee

0:00 Introduction

0:39 The use of postoperative calibrations in Hirschsprung disease: a practice to reconsider?

1:47 Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

2:57 Treatment Facility Case Volume and Disparities in Outcomes of Congenital Diaphragmatic Hernia Cases

4:06 Outro

NCBI - WWW Error Blocked Diagnostic

Beati F, D'Angelo T, Iacusso C, Iacobelli BD, Scorletti F, Valfré L, Pellegrino C, Bagolan P, Conforti A, Fusaro F. The use of postoperative calibrations in Hirschsprung disease: a practice to reconsider? Pediatr Surg Int. 2024 Jul 5;40(1):176. doi: 10.1007/s00383-024-05761-6. PMID: 38967682.

NCBI - WWW Error Blocked Diagnostic

Slidell MB, McAteer J, Miniati D, Sømme S, Wakeman D, Rialon K, Lucas D, Beres A, Chang H, Englum B, Kawaguchi A, Gonzalez K, Speck E, Villalona G, Kulaylat A, Rentea R, Yousef Y, Darderian S, Acker S, St Peter S, Kelley-Quon L, Baird R, Baerg J. Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations (A Systematic Review From the American Pediatric Surgical Association Outcomes & Evidence Based Practice Committee). J Pediatr Surg. 2024 Aug;59(8):1408-1417. doi: 10.1016/j.jpedsurg.2024.03.044. Epub 2024 Apr 30. PMID: 38796391.

NCBI - WWW Error Blocked Diagnostic

Peiffer SE, Mehl SC, Powell P, Lee TC, Keswani SG, King A. Treatment Facility Case Volume and Disparities in Outcomes of Congenital Diaphragmatic Hernia Cases. J Pediatr Surg. 2024 May;59(5):825-831. doi: 10.1016/j.jpedsurg.2024.01.042. Epub 2024 Feb 4. PMID: 38413264.

We’re back with 21st episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review articles covering the most interesting and relevant topics in the field.

These articles are either chosen by JPS editors or our collaborators. We present these reviews as short news pieces with a summarization of key points.

Whether you're a trainee, attending, or an advanced medical professional, tune in to our podcast for a dose of medical knowledge in every episode. Stay up to date on the latest trends and advancements in pediatric surgery with "Quick Literature Updates".

Host: Em Gootee

NCBI - WWW Error Blocked Diagnostic

Li S, Wang J, Li M, Zhang Z, Mi T, Wu X, Wang Z, Jin L, He D. Efficacy and late kidney effects of nephron-sparing surgery in the management of unilateral Wilms tumor: a systematic review and meta-analysis. Pediatr Surg Int. 2023 Dec 27;40(1):29. doi: 10.1007/s00383-023-05611-x. PMID: 38150145.

NCBI - WWW Error Blocked Diagnostic

Gillipelli SR, Pio L, Losty PD, Abdelhafeez AH. Female Fertility Cryopreservation Outcomes in Childhood Cancer: A Systematic Review. J Pediatr Surg. 2024 Aug;59(8):1564-1568. doi: 10.1016/j.jpedsurg.2024.02.015. Epub 2024 Mar 1. PMID: 38519388.

NCBI - WWW Error Blocked Diagnostic

Witte AB, Van Arendonk K, Bergner C, Bantchev M, Falcone RA Jr, Moody S, Hartman HA, Evans E, Thakkar R, Patterson KN, Minneci PC, Mak GZ, Slidell MB, Johnson M, Landman MP, Markel TA, Leys CM, Cherney Stafford L, Draper J, Foley DS, Downard C, Skaggs TM, Lal DR, Gourlay D, Ehrlich PF. Venous Thromboembolism Prophylaxis in High-Risk Pediatric Trauma Patients. JAMA Surg. 2024 Oct 1;159(10):1149-1156. doi: 10.1001/jamasurg.2024.2487. PMID: 39083300; PMCID: PMC11292570.

In this session from the 12th Annual Update Course in Pediatric Surgery, Dr. Jill Larson from Ann & Robert H. Lurie Children’s Hospital outlines key strategies for preventing and managing the most common pediatric fractures—just in time for the seasonal surge.

Key Highlights:

• Timing of fractures: Fracture season peaks in spring, summer, and surprisingly, October—timing your prevention efforts matters

• Top five fracture types: Wrist, ankle, elbow, forearm, and tibia fractures are the most common injuries treated in pediatric orthopedics.

• What to treat—and how: Dr. Larson explains which fractures can be managed conservatively (e.g., buckle or greenstick) and which may need surgery (e.g., displaced triplane fractures).

• Casting and immobilization tips: Includes guidance on when to splint, when to cast, and how long to monitor growth plate–involved injuries.

• Injury prevention insights: From trampoline accidents to lawnmower-related trauma, this session covers key safety risks and how to address them proactively.

• Nutrition and bone health: Vitamin D deficiency and obesity are contributing factors—highlighting the need for a holistic approach to fracture prevention.

This session provides practical, seasonal insights for pediatric providers—and equips teams with the knowledge to protect growing bones before peak fracture months arrive.

In this session from the 12th Annual Update Course in Pediatric Surgery, Dr. Bhargava Mullapudi (Children’s Mercy Kansas City) presents updated strategies in Wilms tumor management, exploring how tumor biology and global guidelines are shaping decisions on surgery vs chemotherapy first.

Key Highlights:

• COG vs SIOP Guidelines: North American centers (COG) typically favor primary surgery, while European protocols (SIOP) begin with chemotherapy—highlighting major global practice differences.
• Impact of Tumor Genetics: Loss of heterozygosity (LOH) at chromosomes 1p and 16q, as well as gain of 1q, influence chemotherapy decisions even in lower-stage disease.
• Staging and Size Aren’t Enough: While age and tumor weight are considered, biological markers ultimately guide treatment, challenging simplified “under 2 years / under 550g” rules.
• Shifting Practice Patterns: Even for Stage I tumors, presence of LOH may justify adding chemotherapy, depending on evolving Children’s Oncology Group recommendations.
• Pathology-Informed Protocols: Surgeons must often pause for biological profiling before placing ports or initiating adjuvant therapy.

This presentation underscores the importance of precision medicine in Wilms tumor care—and how treatment pathways increasingly rely on molecular markers, not just stage and weight.

In this session from the 12th Annual Update Course in Pediatric Surgery, Drs. Rebecca Stark and Steven Lee from Seattle Children’s Hospital walk through the timing, technique, and evolving protocols for performing ECMO and surgical repair in cases of severe congenital diaphragmatic hernia (CDH).

Key Highlights:

• VA ECMO with bivalirudin: The presenters advocate for bivalirudin as a preferred anticoagulant over heparin due to its short half-life, predictable response, and ease of control—making it ideal for ECMO patients requiring surgery.
• Dilute thrombin time for monitoring: They highlight a lab-friendly technique for monitoring bivalirudin using dilute thrombin time—5x more specific and sensitive than PTT and easily implementable in any lab.
• Safe and timely surgical repair on ECMO: Early CDH repair (within 8–24 hours of ECMO initiation) can be performed with minimal bleeding and less tissue edema when using bivalirudin and meticulous technique.
• Institutional buy-in for early repair: The team underscores the importance of cross-disciplinary collaboration—including neonatologists, anesthesiologists, and weekend OR availability—to enable early ECMO repair protocols.
• Risk-stratified vs early repair strategy: Some centers risk-stratify ECMO patients, but Stark and Lee favor universal early repair to avoid complications associated with delayed surgery in non-weanable patients.
• Evolving national practices: As of this year, over 80% of CDH Study Group centers are now performing early repair on ECMO—showing how rapidly clinical protocols can shift with strong supporting data.

This session emphasizes the role of proactive planning, team-based decision-making, and flexible protocol development in improving outcomes for neonates with severe CDH requiring ECMO.

In this session from the 12th Annual Update Course in Pediatric Surgery, Dr. Margaret Mutch from Australia walks through the complexities of chest wall reconstruction following thoracic osteosarcoma resection in a pediatric patient.

Key Highlights:

• Massive resection and reconstruction: A 14-year-old patient underwent an aggressive en bloc resection involving ribs 4–7 and vertebral bodies T4–T7. The team used a combination of resorbable molded plates, Permacol mesh, and Gore-Tex patches to stabilize and recreate the chest wall structure.

• Soft tissue closure with latissimus flap: A latissimus dorsi flap was mobilized for robust coverage, reducing dead space and supporting tissue healing over the reconstructed area.

• Use of ROLL technique for lymph node excision: The team employed radio-guided occult lesion localization (ROLL) using Technetium-99 to precisely identify and remove targeted lymph nodes.

• Managing early complications: Postoperative challenges included sterile seromas, a wound infection, and mild scoliosis—all managed conservatively with good outcomes.

• Addressing recurrence and reoperation: When local recurrence occurred 18 months later, a second reconstruction involving the sternum and cement mesh was required, illustrating the long-term complexity of these cases.

• Future outlook for pediatric reconstructions: Dr. Mutch emphasized the lack of standardization in pediatric materials and techniques, pointing toward a future where custom 3D-printed implants and biologics may offer better long-term solutions.

This session highlights the surgical precision, interdisciplinary coordination, and resilience required to manage large-scale reconstructions in growing children—where both oncologic control and functional outcomes must be balanced.